Results 21 to 30 of about 12,421 (291)

Dextran-enhanced CEST MRI reveals the size effect of BBB dysfunction associated with neuroinflammation

open access: yesVeins and Lymphatics, 2022
INTRODUCTION: The blood-brain barrier (BBB) is compromised in multiple central nervous system (CNS) disorders associated with neuroinflammation, including multiple sclerosis (MS).
Wenshen Wang   +3 more
doaj   +1 more source

Intrastriatal convection-enhanced delivery results in widespread perivascular distribution in a pre-clinical model

open access: yesFluids and Barriers of the CNS, 2012
Background Convection-enhanced delivery (CED), a direct method for drug delivery to the brain through intraparenchymal microcatheters, is a promising strategy for intracerebral pharmacological therapy.
Barua Neil U   +6 more
doaj   +1 more source

In vitro fermentation of linear and α-1,2-branched dextrans by the human fecal microbiota

open access: yes, 2011
The role of structure and molecular weight in fermentation selectivity in linear α-1,6 dextrans and dextrans with α-1,2 branching was investigated. Fermentation by gut bacteria was determined in anaerobic, pH-controlled fecal batch cultures after 36h ...
Sarbini, Shahrul Razid
core   +2 more sources

Optical clearing of flowing blood using dextrans with spectral domain optical coherence tomography [PDF]

open access: yes, 2008
Spectral domain optical coherence tomography (SDOCT) images have been used to investigate the mechanism of optical clearing in flowing blood using dextrans.
Yu, Lingfeng   +2 more
core   +1 more source

Dextranas em açúcares do estado de São Paulo Dextrans in lugars from São Paulo State

open access: yesQuímica Nova, 2008
The characterization of dextran in sugars by size exclusion chromatography (SEC) has been carried out according to the number-average molecular weight (Mn), the weight-average molecular weight (Mw), the Z-average molecular weight (Mz), and the ...
Francisco Wendel Batista de Aquino   +1 more
doaj   +1 more source

BINDING OF PIPRINHYDRINATE TO PLASMA PROTEINS AND THEIR SUBSTITUTES [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1994
The binding of piprinhydrinate to bovine serum albumin (BSA) was studied in isotonic Sorensen's phosphate buffer pH 7.4 at 25±1°C, using equilibrium dialysis technique.
M. Abd ElRahman   +4 more
doaj   +1 more source

A systematic approach to study the pH-dependent release, productivity and product specificity of dextransucrases

open access: yesMicrobial Cell Factories, 2019
Background Dextransucrases are extracellular enzymes, which catalyze the formation of α-1→6-linked glucose polymers from sucrose. These enzymes are exclusively expressed by lactic acid bacteria, which commonly acidify the extracellular environment due to
Jonas Schmid   +3 more
doaj   +1 more source

STRUCTURAL STUDIES ON CLINICAL DEXTRANS: PART 1. METHYLATION AND PERIODATE OXIDATION STUDIES

open access: yes, 1959
Determinations have been made of the structures of four clinical dextrans, i.e. partially depolymerized dextrans which, in solution, are used as blood-volume expanders.
K. C. B. Wilkie, J. K. N. Jones
core   +1 more source

Gold Nanoparticle-Mediated Photoporation Enables Delivery of Macromolecules over a Wide Range of Molecular Weights in Human CD4+ T Cells

open access: yesCrystals, 2019
The modification of CD4+ T cells with exogenous nucleic acids or proteins is a critical step in several research and therapeutic applications, such as HIV studies and cancer immunotherapies.
Laurens Raes   +10 more
doaj   +1 more source

Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

open access: yeseLife, 2017
Transport of solutes through brain involves diffusion and convection. The importance of convective flow in the subarachnoid and paravascular spaces has long been recognized; a recently proposed ‘glymphatic’ clearance mechanism additionally suggests that ...
Alex J Smith   +4 more
doaj   +1 more source

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