Results 41 to 50 of about 11,586 (297)
Formation of Microcages from a Collagen Mimetic Peptide via Metal-Ligand Interactions
Molecules, 2021 Here, the hierarchical assembly of a collagen mimetic peptide (CMP) displaying four bipyridine moieties is described. The CMP was capable of forming triple helices followed by self-assembly into disks and domes.
Jeremy Gleaton +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
STRUCTURAL STUDIES ON CLINICAL DEXTRANS: PART 1. METHYLATION AND PERIODATE OXIDATION STUDIES
, 1959 Determinations have been made of the structures of four clinical dextrans, i.e. partially depolymerized dextrans which, in solution, are used as blood-volume expanders.
K. C. B. Wilkie, J. K. N. Jones
core +1 more source
Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers
Scientific Reports, 2020 Enteric bacteria and/or their products are necessary for doxorubicin (DXR)-induced small intestine mucosal damage. While DXR does not induce gross loss of epithelium, others have shown elevated serum endotoxin after DXR administration.
Paul Cray +3 more
doaj +1 more source
Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts
Advanced Functional Materials, EarlyView.Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett +15 more
wiley +1 more source
Advanced Functional Materials, EarlyView.We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
wiley +1 more source
Anti-hygroscopic effect of dextrans in herbal formulations
, 2008 Equilibrium moisture sorptions of two dried aqueous herbal extracts and their mixtures with dextrans of various molecular weights were investigated as a function of relative humidity at ambient temperature, and the data were analyzed by both the ...
Law, Marcus W.L. +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng +16 more
wiley +1 more source
Optical clearing of flowing blood using dextrans with spectral domain optical coherence tomography [PDF]
, 2008 Spectral domain optical coherence tomography (SDOCT) images have been used to investigate the mechanism of optical clearing in flowing blood using dextrans.
Yu, Lingfeng +2 more
core +1 more source
Investigation of the spatiotemporal responses of nanoparticles in tumor tissues with a small-scale mathematical model. [PDF]
PLoS ONE, 2013 The transport and accumulation of anticancer nanodrugs in tumor tissues are affected by many factors including particle properties, vascular density and leakiness, and interstitial diffusivity.
Cheng-Ying Chou +4 more
doaj +1 more source