Results 31 to 40 of about 11,586 (297)
Cytosolic Uptake of Large Monofunctionalized Dextrans
, 2018 Dextrans are a versatile class of polysaccharides with applications that span medicine, cell biology, food science, and consumer goods. Here, we report on a new type of large monofunctionalized dextran that exhibits unusual properties: efficient ...
Henry R. Kilgore (3917024) +2 more
core +1 more source
Inducing an LCST in hydrophilic polysaccharides via engineered macromolecular hydrophobicity
Scientific Reports, 2023 Thermoresponsive polysaccharide-based materials with tunable transition temperatures regulating phase-separated microdomains offer substantial opportunities in tissue engineering and biomedical applications.
Saniya Yesmin Bubli +5 more
doaj +1 more source
High and Low Molecular Weight Fluorescein Isothiocyanate (FITC)–Dextrans to Assess Blood-Brain Barrier Disruption: Technical Considerations [PDF]
, 2010 This note is to report how histological preparation techniques influence the extravasation pattern of the different molecular sizes of fluorescein isothiocyanate (FITC)-dextrans, typically used as markers for blood-brain barrier leakage.
Jörg Bredno +11 more
core +1 more source
Crystals, 2019 The modification of CD4+ T cells with exogenous nucleic acids or proteins is a critical step in several research and therapeutic applications, such as HIV studies and cancer immunotherapies.
Laurens Raes +10 more
doaj +1 more source
Pakistan Armed Forces Medical Journal, 2020 Objective: To compare the efficacy of sodium hyaluronate, hydroxypropyl methylcellulose/dextran and polypropylene/polyethylene glycol based commercial artificial tear products using the noninvasive tear film breakup time.
Faisal Aziz Khan +2 more
doaj
eLife, 2017 Transport of solutes through brain involves diffusion and convection. The importance of convective flow in the subarachnoid and paravascular spaces has long been recognized; a recently proposed ‘glymphatic’ clearance mechanism additionally suggests that ...
Alex J Smith +4 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Large molecules from the cerebrospinal fluid enter the optic nerve but not the retina of mice
Fluids and Barriers of the CNSIt has been proposed that cerebrospinal fluid (CSF) can enter and leave the retina and optic nerve along perivascular spaces surrounding the central retinal vessels as part of an aquaporin-4 (AQP4) dependent ocular ‘glymphatic’ system.
Xiao J. Tong +4 more
doaj +1 more source
Biomaterials Research, 2020 Background Transdermal delivery is of great importance for the effective delivery of bioactive or therapeutic agents into a body. The microporation device based on radiofrequency can be used to enhance delivery efficiency by removing the epidermis layer.
Guk Young Ahn +3 more
doaj +1 more source
Aqueous Angiography: Real-Time and Physiologic Aqueous Humor Outflow Imaging. [PDF]
PLoS ONE, 2016 PURPOSE:Trabecular meshwork (TM) bypass surgeries attempt to enhance aqueous humor outflow (AHO) to lower intraocular pressure (IOP). While TM bypass results are promising, inconsistent success is seen.
Sindhu Saraswathy +6 more
doaj +1 more source