Results 51 to 60 of about 11,586 (297)

The C-Terminal Domain of Liquorilactobacillus nagelii Dextransucrase Mediates the Production of Larger Dextrans Compared to Liquorilactobacillus hordei

Gels, 2022
Dextransucrases released by certain lactic acid bacteria form glucose polymers with predominantly α-1,6-linkages and may be exploited biotechnologically for the tailored production of polysaccharides with application potential.
Julia Bechtner, Verena Hassler, Daniel Wefers, Matthias Ehrmann, Frank Jakob   +4 more
doaj   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Michele D'Orazio, Biagio Palmisano, Silvia Franco, Arianna Mencattini, Roberta Angelini, Eugenio Martinelli, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +17 more
wiley   +1 more source

Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features

Advanced Healthcare Materials, EarlyView.
ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato, Hanan Abumanhal‐Masarweh, Martí de Cabo, Pablo Guerra, Marilena Hadjidemetriou, Neus Lozano, Kostas Kostarelos   +6 more
wiley   +1 more source

Di-iodo-l-tyrosine-labelled Dextrans as Molecular Size Markers of Nasal Absorption in the Rat

, 1992
A series of fractionated di-iodo-l-tyrosine-labelled dextrans (DIT dextrans), with a narrow range of number average molecular weights from 1260 to 45 500 Da, was administered intranasally and intravenously to anaesthetized rats.
E H Schacht, A N Fisher, L Illum, S S Davis   +3 more
core   +1 more source

Packed Hydrogel Microfibers as Scaffolds Supporting Dynamic Cellular Behavior and Biomaterial Inks in 3D Printing

Advanced Healthcare Materials, EarlyView.
Packed hydrogel microfiber (PHM) materials consist of flexible and high aspect ratio hydrogel components that, as a bulk material, are simultaneously mechanically robust and dynamic. Cells cultured in or on PHM scaffolds can be influenced by topographical cues or interact with a dynamic environment that permits cell spreading and multicellular ...
M. Gregory Grewal, Remington M. Martinez, Georgia T. Helein, Montserrath G. Ibarra Rivera, Rodolfo Martinez Jr., Jenna L. Sumey, Steven R. Caliari, Christopher B. Highley   +7 more
wiley   +1 more source

Th17 Cytokines Disrupt the Airway Mucosal Barrier in Chronic Rhinosinusitis

Mediators of Inflammation, 2016
Cytokine mediated changes in paracellular permeability contribute to a multitude of pathological conditions including chronic rhinosinusitis (CRS). The purpose of this study was to investigate the effect of interferons and of Th1, Th2, and Th17 cytokines
Mahnaz Ramezanpour, Sophia Moraitis, Jason L. P. Smith, P. J. Wormald, Sarah Vreugde   +4 more
doaj   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

Determination of glomerular permselectivity to neutral dextrans in the dog

, 1983
The multiple-indicator-dilution (MID) technique was used to separate solute flux (Js) across the glomerular and postglomerular capillaries in vivo. Anesthetized mongrel dogs (n = 20) during mannitol diuresis received a pulse of extracellular indicators ...
C. Whiteside, M. Silverman
core   +1 more source

Chromatographic Separation of Isomaltooligosaccharides on Ion-Exchange Resins: Effect of the Cationic Form

Adsorption Science & Technology, 2012
Prebiotic isomaltooligosaccharides (IMOs) are composed of α-d-glucose units linked by glucosidic α (1Ø6) bonds and they remain intact until reaching the large bowels, where they are metabolized by bifidobacteria and lactobacillus.
M.C. Rabelo, C.S.M. Pereira, S. Rodrigues, A.E. Rodrigues, D.C.S. Azevedo   +4 more
doaj   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source