Results 61 to 70 of about 12,421 (291)
PLoS ONE, 2015 Hypoglycemia impairs blood-brain barrier (BBB) endothelial function; a major hallmark in the pathogenesis of various CNS disorders. Previously, we have demonstrated that prolonged hypoglycemic exposure down-regulated BBB endothelial NF-E2 related factor ...
Ravi K Sajja +2 more
doaj +1 more source
INTERACTION OF DIMETHINDENE MALEATE WITH BOVINE SERUM ALBUMIN AND PLASMA SUBSTITUTES
Zagazig Journal of Pharmaceutical Sciences, 1994 Binding of dimethindene maleate to bovine serum albumin (BSA) was studied in isotonic Sorensen's phosphate buffer of pH 7.4 at 25°C, using equilibrium dialysis technique.
Bernd Muller +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli +8 more
wiley +1 more source
Determination of glomerular permselectivity to neutral dextrans in the dog
, 1983 The multiple-indicator-dilution (MID) technique was used to separate solute flux (Js) across the glomerular and postglomerular capillaries in vivo. Anesthetized mongrel dogs (n = 20) during mannitol diuresis received a pulse of extracellular indicators ...
C. Whiteside, M. Silverman
core +1 more source
Advanced Healthcare Materials, EarlyView.Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko +7 more
wiley +1 more source
Effect of 100% O2 on passage of uncharged dextrans from blood to lung lymph
, 1986 Since charge as well as size may influence the passage of plasma proteins from blood to lung lymph, we used uncharged dextrans as tracers to study the effects of hyperoxic lung injury on the molecular sieving properties of the pulmonary microcirculation
A. P. Fishman +5 more
core +1 more source
Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization
Advanced Materials, EarlyView.A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab +8 more
wiley +1 more source
Neoplasia: An International Journal for Oncology Research, 2009 Elevated tumor interstitial fluid pressure (TIFP) is a characteristic of most solid tumors. Clinically, TIFP may hamper the uptake of chemotherapeutic drugs into the tumor tissue reducing their therapeutic efficacy.
Matthias Hofmann +8 more
doaj +1 more source
Inverse Design of Nanoparticulate Materials
Advanced Materials, EarlyView.Inverse design shifts nanomaterial development from empirical trial‐and‐error to predictive model‐driven strategies. It can rely on knowledge‐based, data‐based, or hybrid process and property functions. This perspective article provides a practical framework for applying inverse design based on instructive examples. It discusses which modeling approach
Nabi Etienne Traoré +5 more
wiley +1 more source
Capillary Permeability to Narrow-Range Macromolecular Dextrans at Normal and Hypobaric Pressures [PDF]
, 1972 In view of its varied concepts and interpretations, and because of the discrepancies produced by the previous utilization of polydispersed dextrans, a study using extremely narrow-range molecular weight dextran fractions was initiated to reevaluate and ...
Norris, John Anthony
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