Results 61 to 70 of about 38,208 (334)

The C-Terminal Domain of Liquorilactobacillus nagelii Dextransucrase Mediates the Production of Larger Dextrans Compared to Liquorilactobacillus hordei

Gels, 2022
Dextransucrases released by certain lactic acid bacteria form glucose polymers with predominantly α-1,6-linkages and may be exploited biotechnologically for the tailored production of polysaccharides with application potential.
Julia Bechtner, Verena Hassler, Daniel Wefers, Matthias Ehrmann, Frank Jakob   +4 more
doaj   +1 more source

The endothelial glycocalyx prefers albumin for evoking shear stress-induced, nitric oxide-mediated coronary dilatation [PDF]

, 2007
Background: Shear stress induces coronary dilatation via production of nitric oxide ( NO). This should involve the endothelial glycocalyx ( EG). A greater effect was expected of albumin versus hydroxyethyl starch ( HES) perfusion, because albumin seals ...
Bernhard F. Becker, Chang YS, Desjardins C, Dirk Bruegger, Gonzalez-Castillo C, Huxley VH, Joern O. Paul, Kuchan MJ, Leipert B, Markus Rehm, Matthias Jacob, Michael Loetsch, Mochizuki S, Mulivor AW, Peter Conzen, Platts SH, Pohl U, Pries AR, Risau W, Rubanyi GM, Siegel G, Ulrich Welsch, van Haaren P, Vink H, Vink H, Vink H   +25 more
core   +1 more source

The Immobilization of Hyaluronic Acid in 3D Hydrogel Scaffolds Modulates Macrophage Polarization

Advanced Biology, EarlyView.
This study explores the use of collagen‐hyaluronic acid (HA) hydrogels for the 3D culture of macrophages, providing a useful tool for modelling macrophage behavior in tissues and diseases. It highlights how hydrogel composition, mechanical properties, and preparation methods influence macrophage behavior, revealing for the first time that HA's ...
Tiah CL Oates, Jasmin Boyd, Louise Dolan, C de Kergariou, Jingwen Zhu, Ash Toye, Adam W Perriman, Asme Boussahel   +7 more
wiley   +1 more source

Investigation of the spatiotemporal responses of nanoparticles in tumor tissues with a small-scale mathematical model. [PDF]

PLoS ONE, 2013
The transport and accumulation of anticancer nanodrugs in tumor tissues are affected by many factors including particle properties, vascular density and leakiness, and interstitial diffusivity.
Cheng-Ying Chou, Chih-Kang Huang, Kuo-Wei Lu, Tzyy-Leng Horng, Win-Li Lin   +4 more
doaj   +1 more source

Engineering the Hierarchical Porosity of Granular Hydrogel Scaffolds Using Porous Microgels to Improve Cell Recruitment and Tissue Integration

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski, Sina Kheirabadi, Arian Jaberi, Zaman Ataie, Catherine L. Mojazza, Marisa L. Williamson, Anton M. Hjaltason, Aneesh Risbud, Yuanhui Xiang, Amir Sheikhi   +9 more
wiley   +1 more source

Dextran and Insulin in Rats [PDF]

Nature, 1960
WHILE testing the effects of insulin on the circulatory reaction of laboratory rats to dextran, we found that many animals died after combined doses of the two agents which were not lethal when administered separately. The validity of this observation was put to experimental test. Male Sprague-Dawley rats weighing at least 150 gm.
C H Hanna, L. H. Marshall
openaire   +3 more sources

Uptake of macromolecules by cercariae during skin penetration and transformation to schistosomula (Schistosoma mansoni) [PDF]

, 2010
Here, we observed the uptake of membrane-impermeant molecules by cercariae as they penetrate the skin and are transformed into schistosomula. We propose that membrane-impermeant molecules, Lucifer Yellow, Propidium iodide and Hoechst 33258 enter the ...
Alvisi de Oliviera, Fabricia, Coelho, Paulo Marcos Zech, Kusel, John, Lima, Symone Fulgêncio, Mattos, Ana Carolina Alves, McVeigh, Paul, Ribeiro, Fabio, Thornhill, Joyce   +7 more
core   +4 more sources

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

Advanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault, Hannah R.C. Kimmel, Alison C. Nunes, Allison L. Paxhia, Sarah Hashim, Kathryn B.H. Clancy, Gregory H. Underhill, Brendan A.C. Harley   +7 more
wiley   +1 more source

Prevention of acute kidney injury and protection of renal function in the intensive care unit : update 2017 [PDF]

, 2017
Background: Acute kidney injury (AKI) in the intensive care unit is associated with significant mortality and morbidity. Objectives: To determine and update previous recommendations for the prevention of AKI, specifically the role of fluids, diuretics ...
Druml, W, Forni, LG, Groeneveld, ABJ, Honore, PM, Hoste, Eric, Joannidis, M, Ostermann, M, Oudemans-van Straaten, HM, Schetz, Mathias   +8 more
core   +8 more sources

Methodological aspects of determining molecular mass distribution of dextrans by size-exclusion chromatography for various groups of medicines

Регуляторные исследования и экспертиза лекарственных средств, 2018
The article analyses the results of quality evaluation of dextran substances and medicines produced thereof which was carried out by the Institution as part of pre-authorisation testing and involved the analysis of the «molecular mass distribution ...
R. S. Smirnov, E. V. Ivanainen, A. I. Lutseva, O. A. Vaganova, D. A. Orlov   +4 more
doaj