Results 81 to 90 of about 38,524 (332)

Increased Plasma Colloid Osmotic Pressure Facilitates the Uptake of Therapeutic Macromolecules in a Xenograft Tumor Model

Neoplasia: An International Journal for Oncology Research, 2009
Elevated tumor interstitial fluid pressure (TIFP) is a characteristic of most solid tumors. Clinically, TIFP may hamper the uptake of chemotherapeutic drugs into the tumor tissue reducing their therapeutic efficacy.
Matthias Hofmann, Emmet McCormack, Maja Mujic, Maila Roßberg, August Bernd, Jürgen Bereiter-Hahn, Bjørn Tore Gjertsen, Helge Wiig, Stefan Kippenberger   +8 more
doaj   +1 more source

Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability [PDF]

, 2016
Sizing nanomaterials in complex biological fluids, such as blood, remains a great challenge in spite of its importance for a wide range of biomedical applications. In drug delivery, for instance, it is essential that aggregation of protein-based drugs is
Braeckmans, Kevin, Brans, Toon, Broos, Katleen, De Smedt, Stefaan, Demeester, Jo, Libert, Claude, Van Wonterghem, Elien, Vandenbroucke, Roosmarijn, Xiong, Ranhua   +8 more
core   +2 more sources

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

The Nuclear Envelope Lamina Network Has Elasticity and a Compressibility Limit Suggestive of a Molecular Shock Absorber [PDF]

, 2004
Author Posting © Journal of Cell Science, 2004. This article is posted here by permission of Journal of Cell Science for personal use, not for redistribution.
Kahn, Samuel
core   +1 more source

Interconnected Porous Hydrogels with Tunable Anisotropy Through Aqueous Emulsion Bioprinting

Advanced Functional Materials, EarlyView.
A 3D bioprintable microporous bioink is developed using an aqueous two‐phase system (ATPS) composed of extracellular matrix (ECM) mimetic biopolymers. The ATPS bioink enables the fabrication of interconnected porous architectures with up to 70% porosity, supporting long‐term cell viability and 3D cell alignment, enabling a simultaneous generation of ...
Hugo Edgar‐Vilar, Francisca P. Correia, Inês M. Freitas, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Effect of Various Infusion Solutions on Microrheology

Общая реаниматология, 2010
Objective: to evaluate the in vitro and in vivo effects of various infusion solutions on red blood cell rheology in the early posttraumatic period. Material and methods.
V. V. Moroz, L. V. Gerasimov, A. A. Isakova, Yu. V. Marchenkov, E.P. Rodionov   +4 more
doaj   +1 more source

Microneedle‐Based Biofertilizer Delivery Improves Plant Growth Through Microbiome Engineering

Advanced Functional Materials, EarlyView.
This figure shows how microneedles are used to deliver biofertilizers to enhance plant growth through microbial migration, metabolic reprogramming, and changes in plant endogenous microbiome. Abstract This study presents a microneedle‐based system for the delivery of rhizospheric biofertilizers into plant tissues to enhance growth.
Zhicheng Le, Sevugan Mayalagu, Cheng‐Yen Chen, Raktim Bhattacharya, Abhishek Gupta, Jingyuan Li, Zhi Wei Norman Teo, Yufeng Shou, Arya Gopinath MP, Danni Zhong, Tedrick Thomas Salim Lew, Hao Yu, Naweed I. Naqvi, Sanjay Swarup, Andy Tay   +14 more
wiley   +1 more source

Pseudomonas aeruginosa Exoprotein-Induced Barrier Disruption Correlates With Elastase Activity and Marks Chronic Rhinosinusitis Severity

Frontiers in Cellular and Infection Microbiology, 2019
Background:Pseudomonas aeruginosa causes severe chronic respiratory diseases and is associated with recalcitrant chronic rhinosinusitis (CRS). P.
Jian Li, Jian Li, Jian Li, Mahnaz Ramezanpour, Stephanie A. Fong, Clare Cooksley, Jae Murphy, Masanobu Suzuki, Masanobu Suzuki, Alkis J. Psaltis, Peter John Wormald, Sarah Vreugde   +11 more
doaj   +1 more source

Gaudichaudione H Inhibits Inflammatory Responses in Macrophages and Dextran Sodium Sulfate-Induced Colitis in Mice [PDF]

, 2020
Yiwen Jiang, Lianbo Xiao, Wenwei Fu, Yue‐Xun Tang, Peeraphong Lertnimitphun, Na‐Mi Kim, Changwu Zheng, Hongsheng Tan, Yue Lu, Hong‐Xi Xu   +9 more
openalex   +1 more source

DEAE-Dextran Coated AgNPs: A Highly Blendable Nanofiller Enhances Compressive Strength of Dental Resin Composites [PDF]

, 2022
Shabia Azhar, Nosheen Fatima Rana, Amer Sohail Kashif, Tahreem Tanweer, Iqra Shafique, Farid Menaa   +5 more
openalex   +1 more source