Results 1 to 10 of about 422,858 (337)

The Glycosylphosphatidylinositol-Anchored DFG Family Is Essential for the Insertion of Galactomannan into the β-(1,3)-Glucan–Chitin Core of the Cell Wall of Aspergillus fumigatus

mSphere, 2019
The fungal cell wall is a complex and dynamic entity essential for the development of fungi. It is composed mainly of polysaccharides that are synthetized by protein complexes.
Laetitia Muszkieta, Thierry Fontaine, Rémi Beau, Isabelle Mouyna, Marian Samuel Vogt, Jonathan Trow, Brendan P. Cormack, Lars-Oliver Essen, Gregory Jouvion, Jean-Paul Latgé   +9 more
doaj   +2 more sources

Integrated broadband and high-efficiency difference frequency generation [PDF]

Nature Communications
High-efficiency integrated difference frequency generation (DFG) has long been pursued for optical communications and signal processing. Recent developments of the thin-film lithium niobate platform enable strong optical confinement in nanoscale ...
Haoran Li, Jingyan Guo, Fei Huang, He Gao, Hanwen Li, Huan Li, Yaocheng Shi, Zejie Yu, Daoxin Dai   +8 more
doaj   +2 more sources

Structural Elucidation of the DFG-Asp in and DFG-Asp out States of TAM Kinases and Insight into the Selectivity of Their Inhibitors

Molecules, 2014
Structural elucidation of the active (DFG-Asp in) and inactive (DFG-Asp out) states of the TAM family of receptor tyrosine kinases is required for future development of TAM inhibitors as drugs.
Abdellah Messoussi, Lucile Peyronnet, Clémence Feneyrolles, Gwénaël Chevé, Khalid Bougrin, Aziz Yasri   +5 more
doaj   +2 more sources

Lead Discovery of Type II BRAF V600E Inhibitors Targeting the Structurally Validated DFG-Out Conformation Based upon Selected Fragments

Molecules, 2016
The success of the first approved kinase inhibitor imatinib has spurred great interest in the development of type II inhibitors targeting the inactive DFG-out conformation, wherein the Phe of the DFG motif at the start of the activation loop points into ...
Qingwen Zhang, Xuejin Zhang, Qidong You
doaj   +2 more sources

Characterization data of reference materials used for phase II of the priority program DFG SPP 2005 “Opus Fluidum Futurum – Rheology of reactive, multiscale, multiphase construction materials”

Data in Brief, 2023
A thorough characterization of base materials is the prerequisite for further research. In this paper, the characterization data of the reference materials (CEM I 42.5 R, limestone powder, calcined clay and a mixture of these three components) used in ...
U. Pott, C. Crasselt, N. Fobbe, M. Haist, M. Heinemann, S. Hellmann, D. Ivanov, C. Jakob, D. Jansen, L. Lei, R. Li, J. Link, D. Lowke, V. Mechtcherine, J. Neubauer, D. Nicia, J. Plank, S. Reißig, T. Schäfer, C. Schilde, W. Schmidt, C. Schröfl, T. Sowoidnich, B. Strybny, N. Ukrainczyk, J. Wolf, P. Xiao, D. Stephan   +27 more
semanticscholar   +1 more source

Design and development of photoswitchable DFG-Out RET kinase inhibitors.

European journal of medicinal chemistry, 2022
REarranged during Transfection (RET) is a transmembrane receptor tyrosine kinase that is required for development of multiple human tissues, but which is also an important contributor to human cancers.
Yongjin Xu, Chunxia Gao, M. Andréasson, L. Håversen, Marta Carrasco, Cassandra L. Fleming, T. Lundbäck, Joakim Andréasson, M. Grøtli   +8 more
semanticscholar   +1 more source

Optical Terahertz Sources Based on Difference Frequency Generation in Nonlinear Crystals

Crystals, 2022
Terahertz (THz) sources, ranging from 0.1 THz to 10 THz, between microwaves and infrared waves, have important applications in spectral detection, medical imaging, communication, etc.
Yang Liu, Kai Zhong, Aiqiang Wang, Mengchen Zhou, Shanchuang Li, Lu Gao, Ze Zhang   +6 more
doaj   +1 more source

Dialogical Family Guidance (dfg)—Development and implementation of an intervention for families with a child with neurodevelopmental disorders

Nursing Open, 2021
Aim To describe the development and implementation of a Dialogical Family Guidance (DFG) intervention, aimed at families with a child with neurodevelopmental disorders (NDD).
Diana Cavonius‐Rintahaka, Anna Liisa Aho, Eva Billstedt, Christopher Gillberg   +3 more
doaj   +1 more source

Predicting inactive conformations of protein kinases using active structures: conformational selection of type-II inhibitors. [PDF]

PLoS ONE, 2011
Protein kinases have been found to possess two characteristic conformations in their activation-loops: the active DFG-in conformation and the inactive DFG-out conformation. Recently, it has been very interesting to develop type-II inhibitors which target
Min Xu, Lu Yu, Bo Wan, Long Yu, Qiang Huang   +4 more
doaj   +1 more source

Optimization framework for DFG-based automated process discovery approaches

Journal of Software and Systems Modeling, 2021
The problem of automatically discovering business process models from event logs has been intensely investigated in the past two decades, leading to a wide range of approaches that strike various trade-offs between accuracy, model complexity, and ...
Adriano Augusto, M. Dumas, Marcello La Rosa, S. Leemans, S. vanden Broucke   +4 more
semanticscholar   +1 more source