Results 11 to 20 of about 422,858 (337)
Design and development of a photoswitchable DFG-out kinase inhibitor.
Chemical Communications, 2021 We report the synthesis and characterisation of a photoswitchable DFG-out kinase inhibitor. Photocontrol of the target kinase in both enzymatic and living cell assays is demonstrated.
Yongjin Xu +5 more
semanticscholar +1 more source
Structure of mitogen-activated protein kinase kinase 1 in the DFG-out conformation.
Acta Crystallographica Section F Structural Biology Communications, 2021 Eukaryotic protein kinases contain an Asp-Phe-Gly (DFG) motif, the conformation of which is involved in controlling the catalytic activity, at the N-terminus of the activation segment.
S. Nakae +6 more
semanticscholar +1 more source
Influence of DFG-STYK1/NOK on cell proliferation and G1/S distribution in mouse fibroblast cell line NIH3T3 [PDF]
Jichu yixue yu linchuang, 2021 Objective To investigate the effects of NOK added DFG motif on proliferation and G1/S distribution of NIH3T3 cells. Methods SWISS MODEL homologous modeling was used to confirm the location of DFG addition; we used CCK-8 and MTT methods to measure the ...
CHEN Jian-miao
doaj
Scientific Reports, 2020 Glycogen synthase kinase-3β (GSK3β) controls many physiological pathways, and is implicated in many diseases including Alzheimer’s and several cancers.
Meenakshisundaram Balasubramaniam +7 more
semanticscholar +1 more source
bioRxiv, 2020 Selectivity remains a challenge for ATP-mimetic kinase inhibitors, an issue that may be overcome by targeting unique residues or binding pockets. However, to date only few strategies have been developed.
M. Schröder +5 more
semanticscholar +1 more source
On Ladder Diagrams Compilation and Synthesis to FPGA Implemented Reconfigurable Logic Controller
Advances in Electrical and Electronic Engineering, 2014 The paper presents synthesis process of a hardware implemented reconfigurable logic controller from a ladder diagram according to IEC61131-3 requirements. It is focused on the originally developed a high-performance LD processing method.
Adam Milik
doaj +1 more source
Advances in Oral and Maxillofacial Surgery, 2023 This systematic review was performed to compare the dermis fat graft (DFG) to the conventional temporalis myofascial flap (TMF) used as Interpositional material in the management of temporomandibular joint ankylosis (TMJA).
Ashutosh Kumar Singh +5 more
doaj +1 more source
Pump-Probe X-ray Holographic Imaging of Dynamic Magnetization Processes Down to the Femtosecond Timescale [PDF]
, 2015 Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Eisebitt, Stefan
core +2 more sources
LAS:eR – Einblicke in das Pilotsystem
o-bib. Das offene Bibliotheksjournal, 2018 Im Rahmen des DFG-Projekts ERMS – Electronic Resource Management System entwickelt die LAS:eR-Projektgruppe ein herstellerunabhängiges ERMS auf Open Source Basis zur Organisation und Verwaltung von elektronischen Ressourcen unter Verwendung der Global ...
Melanie Engels, Daniel A. Rupp
doaj +1 more source
Forschungsdatenmanagement in DFG-Sonderforschungsbereichen
Bausteine Forschungsdatenmanagement, 2020 Dieser Artikel stellt die Ergebnisse einer Befragung zum Forschungsdatenmanagement und zur Forschungsdateninfrastruktur in DFG-Sonderforschungsbereichen vor, die im Herbst 2018 im Vorfeld eines Workshops zum selben Thema durchgeführt wurde und an der ...
Claudia Engelhardt
doaj +1 more source