Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) [PDF]
Frontiers in Neuroendocrinology, 2009 DHEA and DHEAS are steroids synthesized in human adrenals, but their function is unclear. In addition to adrenal synthesis, evidence also indicates that DHEA and DHEAS are synthesized in the brain, further suggesting a role of these hormones in brain function and development.
Nicole, Maninger +4 more
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THE PROTECTIVE EFFECT OF COQ10, DHEA AND THEIR COMBINATION IN REDUCED EMBRYOTOXICITY AND TERATOGENICITY FOR NORFLOXACIN IN PREGNANT FEMALE RATS [PDF]
Basrah Journal of Veterinary Research, 2018 This study was designed to evaluate the protective effect of CoQ10 and DHEA and their combination of norfloxacin induced embryotoxicity and teratogenicity in pregnant female rats and their fetuses. Twenty pregnant rats were divided equally into 5 groups,
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Perceived stress at work is associated with lower levels of DHEA-S. [PDF]
PLoS ONE, 2013 BACKGROUND: It is known that long-term psychosocial stress may cause or contribute to different diseases and symptoms and accelerate aging.
Anna-Karin Lennartsson +4 more
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Metabolites, 2022 The regulation of DHEA-sulfate by steroid sulfotransferase (SULT) and steryl-sulfatase (STS) enzymes is a vital process for the downstream formation of many steroid hormones. DHEA-sulfate is the most abundant steroid hormone in the human body; thus, DHEA-
Ajna Hamidovic +5 more
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Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids [PDF]
Proceedings of the National Academy of Sciences, 1998 The observation was made that dehydroepiandrosterone (DHEA), as the unconjugated steroid, and its sulfate ester (DHEAS) are present in the brain of adult male rats (1). This finding was unforeseen because the rodent steroidogenic glands, including the adrenals, do not secrete significant amounts of DHEA (2).
E E, Baulieu, P, Robel
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THE MECHANISMS OF SECONDARY OVARIAN FAILURE AT OPERATIONS ON THE PELVIC ORGANS (EXPERIMENTAL STUDY)
Акушерство, гинекология и репродукция, 2016 Objective - to establish a hysterectomy role in formation of secondary ovarian failure and to estimate possibility of application of DHEA. Materials and Methods. Sexually mature female rats outbred Wistar. Main group: 1a - hysterectomy + salpingectomy (n=
I. A. Petrov +6 more
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Association between prenatal androgens and cord blood androgens, a path analysis
Scientific Reports, 2023 To determine association paths between prenatal androgens and cord blood androgens. The concentrations of T, FT, DHT, DHEA and SHBG in prenatal venous blood and cord blood were measured in 342 pregnant women and their neonates.
Hui Xu +9 more
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Analyzing Serum Level Changes in Dehydroepiandrosterone Sulfate, Dihydrotestosterone, Progesterone, and Prolactin after Radioactive Iodine Treatment for Papillary Thyroid Carcinoma [PDF]
Iranian Journal of Medical PhysicsIntroduction: Effective treatment of papillary thyroid carcinoma (PTC) is total thyroidectomy which is followed by radioactive iodine therapy (RIT) to ablate pathologic thyroid remnants and treat metastatic tumors.
Mehrosadat Alavi +2 more
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DHEA in Elderly Women and DHEA or Testosterone in Elderly Men
Obstetrical & Gynecological Survey, 2006 Dehydroepiandrosterone (DHEA) and testosterone are widely promoted as antiaging supplements, but the long-term benefits, as compared with potential harm, are unknown.We performed a 2-year, placebo-controlled, randomized, double-blind study involving 87 elderly men with low levels of the sulfated form of DHEA and bioavailable testosterone and 57 elderly
NAIR KS +17 more
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BMC Musculoskeletal Disorders, 2021 Background Dehydroepiandrosterone (DHEA), an adrenal steroid, has a protective role against diabetes. This study aimed to investigate the in vitro and in vivo protective effects of DHEA against high glucose-induced oxidative stress in tenocytes and ...
Shintaro Mukohara +7 more
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