Results 31 to 40 of about 46,464 (291)

Greater Lifetime Stress Exposure Predicts Blunted Cortisol but Heightened DHEA Responses to Acute Stress

Stress and Health, 2018
Although prior research has examined how early adversity and chronic stress exposure relate to hypothalamic-pituitary-adrenal (HPA) axis responses to acute stress, to date, no studies have examined how stressors occurring over the entire lifespan predict
Jovian C W Lam, G. Shields, B. Trainor, George M. Slavich, A. Yonelinas   +4 more
semanticscholar   +1 more source

Vasodilator effects of dehydroepiandrosterone (DHEA) on fetal pulmonary circulation: An experimental study in pregnant sheep. [PDF]

PLoS ONE, 2018
Persistent pulmonary hypertension (PPHN) remains a severe complication of the transition to extra-uterine life with significant morbidity and mortality in the newborns.
Dyuti Sharma, Hélène Coridon, Estelle Aubry, Ali Houeijeh, Véronique Houfflin-Debarge, Rémi Besson, Philippe Deruelle, Laurent Storme   +7 more
doaj   +1 more source

DHEA-induced ovarian hyperfibrosis is mediated by TGF-β signaling pathway

Journal of Ovarian Research, 2018
BackgroundThe polycystic ovary syndrome (PCOS) is a common metabolic and endocrine disorder with pathological mechanisms remain unclear. The following study investigates the ovarian hyperfibrosis forming via transforming growth factor-β (TGF-β) signaling
Daojuan Wang, Wenqing Wang, Q. Liang, Xuan He, Yanjie Xia, S. Shen, Hongwei Wang, Q. Gao, Yong Wang   +8 more
semanticscholar   +1 more source

Low Levels of Dehydroepiandrosterone Sulfate in Younger Burnout Patients. [PDF]

PLoS ONE, 2015
Dehydroepiandrosterone sulphate (DHEA-s) is an anabolic protective hormone of importance for maintenance of health. DHEA-s levels peak in young adults and decline thereafter with age.
Anna-Karin Lennartsson, Töres Theorell, Mark M Kushnir, Ingibjörg H Jonsdottir   +3 more
doaj   +1 more source

Lower DHEA-S levels predict disease and worse outcomes in post-menopausal women with idiopathic, connective tissue disease- and congenital heart disease-associated pulmonary arterial hypertension

European Respiratory Journal, 2018
High oestradiol (E2) and low dehydroepiandrosterone-sulfate (DHEA-S) levels are risk factors for pulmonary arterial hypertension (PAH) in men, but whether sex hormones are related to PAH in women is unknown.
Grayson L. Baird, C. Archer‐Chicko, R. G. Barr, D. Bluemke, A. Foderaro, Jason S. Fritz, Nicholas S. Hill, Steve M Kawut, J. Klinger, João A. C. Lima, Christopher J. Mullin, P. Ouyang, Harold I. Palevsky, Amy J. Palmisicano, D. Pinder, I. Preston, K. Roberts, K. A. Smith, T. Walsh, M. Whittenhall, C. Ventetuolo   +20 more
semanticscholar   +1 more source

Sex-specific effects of serum sulfate level and SLC13A1 nonsense variants on DHEA homeostasis

Molecular Genetics and Metabolism Reports, 2017
Context: Sulfate is critical in the biotransformation of multiple compounds via sulfation. These compounds include neurotransmitters, proteoglycans, xenobiotics, and hormones such as dehydroepiandrosterone (DHEA).
Christina G. Tise, Leslie E. Anforth, Albert E. Zhou, James A. Perry, Patrick F. McArdle, Elizabeth A. Streeten, Alan R. Shuldiner, Laura M. Yerges-Armstrong   +7 more
doaj   +1 more source

The relationship between dehydroepiandrosterone (DHEA), working memory and distraction--a behavioral and electrophysiological approach. [PDF]

PLoS ONE, 2014
Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone-sulphate (DHEAS) have been reported to have memory enhancement effects in humans. A neuro-stimulatory action and an anti-cortisol mechanism of action may contribute to that relation.
Sónia do Vale, Lenka Selinger, João Martin Martins, Ana Coelho Gomes, Manuel Bicho, Isabel do Carmo, Carles Escera   +6 more
doaj   +1 more source

Systemic and local effects of vaginal dehydroepiandrosterone (DHEA): NCCTG N10C1 (Alliance)

Supportive Care in Cancer, 2017
BackgroundDehydroepiandrosterone (DHEA) is helpful for treating vaginal symptoms. This secondary analysis evaluated the impact of vaginal DHEA on hormone concentrations, bone turnover, and vaginal cytology in women with a cancer history ...
D. Barton, L. Shuster, T. Dockter, P. Atherton, Jacqueline M. Thielen, S. Birrell, R. Sood, P. Griffin, S. Terstriep, B. Mattar, J. Lafky, C. Loprinzi   +11 more
semanticscholar   +1 more source

Dehydroepiandrosterone (DHEA) supplementation improves in vitro fertilization outcomes of poor ovarian responders, especially in women with low serum concentration of DHEA-S: a retrospective cohort study

Reproductive Biology and Endocrinology, 2018
BackgroundDehydroepiandrosterone (DHEA) is now widely used as an adjuvant for in vitro fertilization (IVF) cycles in poor ovarian responders (PORs). Several studies showed that DHEA supplementation could improve IVF outcomes of PORs. However, most of the
Chyi-uei Chern, K. Tsui, S. Vitale, San‐Nung Chen, Peng-Hui Wang, A. Cianci, H. Tsai, Z. Wen, Li-Te Lin   +8 more
semanticscholar   +1 more source

Serum Dehydroepiandrosterone (DHEA) and DHEA-Sulfate (DHEA-S) in Alzheimer's Disease and in Cerebrovascular Dementia.

Endocrine Journal, 1996
A decreased concentration of dehydroepiandrosterone sulfate (DHEA-S) in patients with Alzheimer's disease (AD) has been reported but is still controversial. In the present study, serum concentrations of DHEA and DHEA-S were determined in 19 patients with AD, 21 patients with cerebrovascular dementia (CVD) and 45 age- and gender matched elderly control ...
YANASE, TOSHIHIKO, FUKAHORI, MOTOFUMI, TANIGUCHI, SUSUMU, NISHI, YOSHIHIRO, SAKAI, YOSHIYUKI, TAKAYANAGI, RYOICHI, HAJI, MASAFUMI, NAWATA, HAJIME   +7 more
openaire   +3 more sources