Oxidative Medicine and Cellular Longevity, 2014 In recent decades, localized tissue oxidative stress has been implicated as a key component in the development of diabetic retinopathy (DR). Increasing evidence shows that oxidative stress caused by diabetes-induced metabolic abnormalities is the most common mechanism associated with the pathogenesis of DR for both type 1 and type 2 diabetes.
Ying Wu, Luosheng Tang, Baihua Chen
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Indonesian Biomedical Journal, 2017 BACKGROUND: Increasing free radicals and oxidative stress due to chronic hyperglycemia in type-2 diabetes mellitus (DM) promotes the activity of endogenic antioxidative genes. Nuclear factor erythroid 2-related factor 2 (Nrf2) expression and activity are
Asri Hendrawati
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Comparison of Mitochondrial Superoxide Detection Ex Vivo/In Vivo by mitoSOX HPLC Method with Classical Assays in Three Different Animal Models of Oxidative Stress [PDF]
, 2019 Background: Reactive oxygen and nitrogen species (RONS such as H2O2, nitric oxide) are generated within the organism. Whereas physiological formation rates confer redox regulation of essential cellular functions and provide the basis for adaptive stress ...
Ksenija Vujacic-Mirski +9 more
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Increased Diabetes Complications in a Mouse Model of Oxidative Stress Due to ‘Mismatched’ Mitochondrial DNA [PDF]
Associations between chronic diabetes complications and mitochondrial dysfunction represent a subject of major importance, given the diabetes pandemic and high personal and socioeconomic costs of diabetes and its complications.
Michael Zhang +8 more
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The Influence of Diabetes Mellitus and Kidney Dysfunction on Oxidative Stress, a Reflection of the Multisystem Interactions in Aortic Stenosis [PDF]
Progression of aortic stenosis (AS) is aggravated by type 2 Diabetes Mellitus (T2DM) and kidney dysfunction (KD). Oxidative stress is one of the main mechanisms that triggers AS and is also disturbed among subjects with T2DM and KD.
Miryam González-Cebrian +13 more
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Phytochemical Profile and Antidiabetic, Antioxidant, and Anti-Inflammatory Activities of Gypsophila paniculata Ethanol Extract in Rat Streptozotocin-Induced Diabetes Mellitus [PDF]
The present study aimed to investigate the effects of the Gypsophila paniculata ethanol extract (GPEE) on oxidative stress, inflammation, and metabolic markers in a rat model of streptozotocin-induced diabetes mellitus (DM).
Lia-Oxana Usatiuc +9 more
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β-Cell Mitochondrial Dysfunction: Underlying Mechanisms and Potential Therapeutic Strategies
CellsMitochondria are essential for β-cell function, coupling glucose metabolism to ATP production and insulin secretion. In diabetes, β-cell mitochondrial dysfunction arises from oxidative stress, impaired quality control and disrupted dynamics, leading to ...
Radwan Darwish +3 more
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Journal of Scientific Research in ScienceThis research aimed to evaluate the in vitro protective effects of avocado (Persea americana) extract on erythrocyte membrane stability under diabetic conditions.
Naglaa M. Ismail
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Oxidative Stress and Antioxidant Interventions in Type 2 Diabetes
The pathophysiological basis of the onset of type 2 diabetes mellitus (T2DM) focuses on oxidative stress that is precipitated due to an imbalance between reactive oxygen species and antioxidants. Gradual and chronic hyperglycemia, as seen in T2DM, produces ROS, which stimulates cellular damage, inflammation, and insulin resistance.
Aamir Sohail +6 more
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Bacillus cereus acid stress responses [PDF]
, 2009 Bacillus cereus is a ubiquitous Gram-positive organism, which frequently causes foodborne illnesses. The widespread prevalence of B. cereus makes it a common contaminant in fresh foods where it also can cause spoilage.
Mols, J.M.
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