FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
How do adults with cystic fibrosis cope following a diagnosis of diabetes? [PDF]
The official published version of the article can be obtained from the link below.Aim. This paper is a report of a study examining the experience of adults with cystic fibrosis in adapting to the diagnosis of diabetes, a second chronic illness ...
Collins, S, Reynolds, F
core +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
A Review of Machine Learning Techniques for Applied Eye Fundus and Tongue Digital Image Processing with Diabetes Management System [PDF]
Diabetes is a global epidemic and it is increasing at an alarming rate. The International Diabetes Federation (IDF) projected that the total number of people with diabetes globally may increase by 48%, from 425 million (year 2017) to 629 million (year 2045).
arxiv
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Employing Visual Analytics to Understand Worldwide Prevalence and Impact of Diabetes Epidemic [PDF]
The International Diabetes Federation (IDF) has declared diabetes to be one of the largest global health emergencies of the 21st century (International Diabetes Federation).
Jha, Sanjeev+2 more
core +2 more sources
In silico simulation of blood glucose-insulin dynamics using MATLAB-Simulink [PDF]
Diabetes mellitus (DM) is a major public health concern in Malaysia and it continuously increases over years. Based on International Diabetes Federation, there are rising numbers of people having diabetes with 3.6 million people in Malaysia and 463 ...
Abdul Malik, Muhammad Iqbal+2 more
core
Feasibility of Implementing Community Partnerships to Provide Diabetes Prevention Services to Youth [PDF]
Type 2 diabetes (T2D) in youth has increased as a result of the obesity epidemic. Diabetes prevention programming is needed for youth, at risk for T2D, and their families.
Haberlin, Kathryn M.+3 more
core +1 more source
2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2019
The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to ...
semanticscholar +1 more source