Results 51 to 60 of about 6,123,999 (398)

In silico simulation of blood glucose-insulin dynamics using MATLAB-Simulink [PDF]

open access: yes, 2020
Diabetes mellitus (DM) is a major public health concern in Malaysia and it continuously increases over years. Based on International Diabetes Federation, there are rising numbers of people having diabetes with 3.6 million people in Malaysia and 463 ...
Abdul Malik, Muhammad Iqbal   +2 more
core  

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

6. Glycemic Targets: Standards of Care in Diabetes-2023.

open access: yesDiabetes Care, 2022
The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate
Nuha A. ElSayed   +19 more
semanticscholar   +1 more source

Diabetic retinopathy [PDF]

open access: yesPostgraduate Medical Journal, 1984
Involvement of the retinal microvascular vessels is an almost inevitable consequence of long standing diabetes. In the only large scale epidemiology study of a Caucasian population Klein et al. found some degree of retinopathy in up to 97% of patients with insulin dependent diabetes mellitus (IDDM) after about 15 years diabetes duration and in about 60%
openaire   +6 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Epidemiology of Type 2 Diabetes – Global Burden of Disease and Forecasted Trends

open access: yesJournal of Epidemiology and Global Health, 2019
The rising burden of type 2 diabetes is a major concern in healthcare worldwide. This research aimed to analyze the global epidemiology of type 2 diabetes.
Moien A. B. Khan   +5 more
semanticscholar   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

On the occasion of the jubilee of Galina A. Melnichenko

open access: yesСахарный диабет, 2011
28 ноября 2011 г. отмечает свой юбилей Галина Афанасьевна Мельниченко - известный эндокринолог, д.м.н., проф., академик РАМН. Галина Афанасьевна - талантливый ученый, замечательный лектор, неутомимый организатор.
Editorial team Diabetes Mellitus
doaj   +1 more source

Employing Visual Analytics to Understand Worldwide Prevalence and Impact of Diabetes Epidemic [PDF]

open access: yes, 2017
The International Diabetes Federation (IDF) has declared diabetes to be one of the largest global health emergencies of the 21st century (International Diabetes Federation).
Jha, Sanjeev   +2 more
core   +2 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

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