Results 51 to 60 of about 5,587,889 (314)
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez+3 more
wiley +1 more source
Care, Education, protection – the Associação Protectora dos Diabéticis de Portugal goes from strength to strength [PDF]
The Portuguese Diabetes Association is the world’s oldest diabetes association and a senior Member Association of the International Diabetes Federation.
Valente Nabais, Joao
core
BACKGROUND Long-term microvascular and neurologic complications cause major morbidity and mortality in patients with insulin-dependent diabetes mellitus (IDDM).
Diabetes Control+8 more
semanticscholar +1 more source
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek+15 more
wiley +1 more source
Variable Weights Neural Network For Diabetes Classification [PDF]
As witnessed in the past year, where the world was brought to the ground by a pandemic, fighting Life-threatening diseases have found greater focus than ever. The first step in fighting a disease is to diagnose it at the right time. Diabetes has been affecting people for a long time and is growing among people faster than ever. The number of people who
arxiv
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Assessing the effectiveness of a clinic-based diabetes management program in a community setting [PDF]
Diabetes in the United States occurs in approximately 8% of adults.[i] Diabetes, if not treated, can lead to many health problems such as blindness or loss of physical functioning, sometimes leading to amputation. However, Type 2 diabetes can be cured
Lupone, Justin
core +1 more source
Searching for "monogenic diabetes" in dogs using a candidate gene approach [PDF]
BACKGROUND: Canine diabetes is a common endocrine disorder with an estimated breed-related prevalence ranging from 0.005% to 1.5% in pet dogs. Increased prevalence in some breeds suggests that diabetes in dogs is influenced by genetic factors and ...
Catchpole, B+7 more
core +2 more sources
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
The Diabetic Buddy: A Diet Regulator andTracking System for Diabetics [PDF]
The prevalence of Diabetes mellitus (DM) in the Middle East is exceptionally high as compared to the rest of the world. In fact, the prevalence of diabetes in the Middle East is 17-20%, which is well above the global average of 8-9%. Research has shown that food intake has strong connections with the blood glucose levels of a patient.
arxiv