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In silico simulation of blood glucose-insulin dynamics using MATLAB-Simulink [PDF]
Diabetes mellitus (DM) is a major public health concern in Malaysia and it continuously increases over years. Based on International Diabetes Federation, there are rising numbers of people having diabetes with 3.6 million people in Malaysia and 463 ...
Abdul Malik, Muhammad Iqbal+2 more
core
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
6. Glycemic Targets: Standards of Care in Diabetes-2023.
The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate
Nuha A. ElSayed+19 more
semanticscholar +1 more source
Involvement of the retinal microvascular vessels is an almost inevitable consequence of long standing diabetes. In the only large scale epidemiology study of a Caucasian population Klein et al. found some degree of retinopathy in up to 97% of patients with insulin dependent diabetes mellitus (IDDM) after about 15 years diabetes duration and in about 60%
openaire +6 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Epidemiology of Type 2 Diabetes – Global Burden of Disease and Forecasted Trends
The rising burden of type 2 diabetes is a major concern in healthcare worldwide. This research aimed to analyze the global epidemiology of type 2 diabetes.
Moien A. B. Khan+5 more
semanticscholar +1 more source
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona+4 more
wiley +1 more source
On the occasion of the jubilee of Galina A. Melnichenko
28 ноября 2011 г. отмечает свой юбилей Галина Афанасьевна Мельниченко - известный эндокринолог, д.м.н., проф., академик РАМН. Галина Афанасьевна - талантливый ученый, замечательный лектор, неутомимый организатор.
Editorial team Diabetes Mellitus
doaj +1 more source
Employing Visual Analytics to Understand Worldwide Prevalence and Impact of Diabetes Epidemic [PDF]
The International Diabetes Federation (IDF) has declared diabetes to be one of the largest global health emergencies of the 21st century (International Diabetes Federation).
Jha, Sanjeev+2 more
core +2 more sources
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura+8 more
wiley +1 more source