Results 61 to 70 of about 6,202,294 (352)

Amyloid beta and diabetic pathology cooperatively stimulate cytokine expression in an Alzheimer's mouse model [PDF]

, 2020
Background Diabetes is a risk factor for developing Alzheimer's disease (AD); however, the mechanism by which diabetes can promote AD pathology remains unknown.
Fernández Ponce, Cecilia Matilde, García Alloza, Mónica, Hierro-Bujalance, Carmen, Infante-Garcia, Carmen, Ramos-Rodríguez, Juan José, Sankar, Sitara B., Weinstock, Laura D., Wood, Levi B.   +7 more
core   +3 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Attitudes to food and lifestyle choices in women with well-controlled and poorly-controlled type 2 diabetes mellitus from different ethnic groups : a pilot study : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutrition at Massey University [PDF]

, 2005
Type 2 diabetes has reached epidemic proportions in New Zealand, as it has globally. There has also been a dramatic rise in numbers from different ethnic groups attending the Auckland Diabetes Centre, with interpreters in approximately 60 different ...
Sanderson, Lesley
core  

The PPARγ2 P12A polymorphism is not associated with all-cause mortality in patients with type 2 diabetes mellitus [PDF]

, 2016
The high mortality risk of patients with type 2 diabetes mellitus may well be explained by the several comorbidities and/or complications. Also the intrinsic genetic component predisposing to diabetes might have a role in shaping the risk of diabetes ...
Alberico, Federica, Bacci, Simonetta, Cignarelli, Mauro, Copetti, Massimiliano, De Cosmo, Salvatore, Fontana, Andrea, Lamacchia, Olga, Marucci, Antonella, Mercuri, Luana, Pacilli, Antonio, Palena, Antonio, Prudente, Sabrina, Trischitta, Vincenzo, Viti, Raffaella   +13 more
core   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Childhood Type II Diabetes: The Risks and Complications [PDF]

, 2015
Type II Diabetes Mellitus is an endocrine disorder that affects people of all ages. Type II Diabetes was once considered adult-onset diabetes, as it was nearly exclusively diagnosed in adults. Over the last three decades, the number of children diagnosed
Kapke, Danielle R
core   +1 more source

Prevalence of diabetes recorded in mainland China using 2018 diagnostic criteria from the American Diabetes Association: national cross sectional study

British medical journal, 2020
Objective To assess the prevalence of diabetes and its risk factors. Design Population based, cross sectional study. Setting 31 provinces in mainland China with nationally representative cross sectional data from 2015 to 2017.
Yongze Li, D. Teng, Xiaoguang Shi, G. Qin, Yingfen Qin, Huibiao Quan, B. Shi, Hui Sun, J. Ba, Bing Chen, Jian-ling Du, Lanjie He, Xiaoyang Lai, Yanbo Li, H. Chi, Eryuan Liao, Chao Liu, Libin Liu, Xulei Tang, N. Tong, Guixia Wang, Jin-an Zhang, Youmin Wang, Yuan-ming Xue, Li Yan, Jing Yang, Lihui Yang, Yongli Yao, Z. Ye, Qiao Zhang, Lihui Zhang, Jun Zhu, Mei Zhu, G. Ning, Y. Mu, Jiajun Zhao, W. Teng, Z. Shan   +37 more
semanticscholar   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

The Interaction of Type II Diabetes and Gonadal Steroids on Cognition in Middle-Aged Women [PDF]

, 2019
Diabetes is not commonly thought to be a women’s health issue, however, it appears to have an association with increased cognitive impairment in women during menopause as compared to women without diabetes (Espeland et al., 2011).
Bates, Kara A
core   +1 more source