Results 71 to 80 of about 5,587,889 (314)

Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025

Scientific Reports, 2020
Diabetes mellitus is a leading cause of mortality and reduced life expectancy. We aim to estimate the burden of diabetes by type, year, regions, and socioeconomic status in 195 countries and territories over the past 28 years, which provide information ...
Xiling Lin, Yufeng Xu, Xiaowen Pan, Jingya Xu, Yue Ding, Xue Sun, Xiaoxia Song, Yuezhong Ren, P. Shan   +8 more
semanticscholar   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

The Interaction of Type II Diabetes and Gonadal Steroids on Cognition in Middle-Aged Women [PDF]

, 2019
Diabetes is not commonly thought to be a women’s health issue, however, it appears to have an association with increased cognitive impairment in women during menopause as compared to women without diabetes (Espeland et al., 2011).
Bates, Kara A
core   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

The impact of diabetes on multiple avoidable admissions: a cross-sectional study [PDF]

, 2019
Background Multiple admissions for ambulatory care sensitive conditions (ACSC) are responsible for an important proportion of health care expenditures. Diabetes is one of the conditions consensually classified as an ACSC being considered a major public ...
A Wannasri, American Diabetes Association, Ana Patrícia Marques, Bruno Moita, C De Coster, C Fischer, Cátia Gaspar, D. Etxeberria-Lekuona, E Selvin, Edy Kornelius, FB Hu, H Kim, International Diabetes Federation, JM Longman, JN Laditka, JN Struijs, Joana Seringa, João Filipe Raposo, M Matesanz-Fernández, MM Carper, MT Puth, P Zhang, Rui Santana, S Gläser, S Mangini, Seth A. Berkowitz, SI Vuik, SY Jung, T Seuring, WB Weeks   +29 more
core   +3 more sources

International Association of Diabetes and Pregnancy Study Groups Recommendations on the Diagnosis and Classification of Hyperglycemia in Pregnancy

Diabetes Care, 2010
In the accompanying comment letter (1), Weinert summarizes published data from the Brazilian Gestational Diabetes Study (2) and comments on applying International Association of Diabetes and Pregnancy Study Groups (IADPSG) Consensus Panel recommendations
B. Metzger, S. Gabbe, B. Persson, T. Buchanan, P. Catalano, P. Damm, A. Dyer, A. Leiva, M. Hod, John L Kitzmiler, L. Lowe, H. Mcintyre, J. Oats, Y. Omori, M. Schmidt   +14 more
semanticscholar   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Advances in Computer-Aided Diagnosis of Diabetic Retinopathy [PDF]

arXiv, 2019
Diabetic Retinopathy is a critical health problem influences 100 million individuals worldwide, and these figures are expected to rise, particularly in Asia. Diabetic Retinopathy is a chronic eye disease which can lead to irreversible vision loss. Considering the visual complexity of retinal images, the early-stage diagnosis of Diabetic Retinopathy can
arxiv  

Deep Learning Approach to Diabetic Retinopathy Detection [PDF]

arXiv, 2020
Diabetic retinopathy is one of the most threatening complications of diabetes that leads to permanent blindness if left untreated. One of the essential challenges is early detection, which is very important for treatment success. Unfortunately, the exact identification of the diabetic retinopathy stage is notoriously tricky and requires expert human ...
arxiv  

Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes.

New England Journal of Medicine, 2016
BACKGROUND Diabetes confers an increased risk of adverse cardiovascular and renal events. In the EMPA-REG OUTCOME trial, empagliflozin, a sodium-glucose cotransporter 2 inhibitor, reduced the risk of major adverse cardiovascular events in patients with ...
C. Wanner, S. Inzucchi, J. Lachin, D. Fitchett, M. von Eynatten, M. Mattheus, O. Johansen, H. Woerle, U. Broedl, B. Zinman   +9 more
semanticscholar   +1 more source