Results 1 to 10 of about 633,696 (309)

The latest progression of N6-methyladenosine (m6A) RNA modification in diabetes mellitus and diabetic complications [PDF]

Frontiers in Endocrinology
The increasing global prevalence of diabetes mellitus and its complications continues to encourage exploration of novel molecular mechanisms for their prevention and treatment.
Guangyang Yin, Jiajing Hong, Guohui Shan, Cuizhu Xu, Bailin Li, Dongyu Yang   +5 more
doaj   +2 more sources

Therapeutic Potential of Holothuria leucospilota Extract in STZ‐Induced Diabetic Rats: Targeting Inflammation and Apoptosis at the Gene Expression Level [PDF]

Endocrinology, Diabetes & Metabolism
Introduction Chronic inflammation is a key contributor to diabetes pathogenesis. Marine‐derived bioactive compounds offer a promising source of therapeutic agents.
Niloufar Darbandi, Muhanad Yusif Al‐rikabi   +1 more
doaj   +2 more sources

Liraglutide Alleviates Hepatic Steatosis by Activating the TFEB-Regulated Autophagy-Lysosomal Pathway

Frontiers in Cell and Developmental Biology, 2020
Liraglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), has been demonstrated to alleviate non-alcoholic fatty liver disease (NAFLD). However, the underlying mechanism has not been fully elucidated.
Yunyun Fang, Linlin Ji, Chaoyu Zhu, Yuanyuan Xiao, Jingjing Zhang, Junxi Lu, Jun Yin, Jun Yin, Li Wei   +8 more
doaj   +1 more source

Insulin-like growth factors and their carrier proteins in kidneys of rats with experimental diabetes, malignant tumor, and their combination

Бюллетень сибирской медицины, 2022
Persistent hyperglycemia resulting from diabetes mellitus causes microvascular lesions and long-term diabetic complications, such as nephropathy.The aim of the study was to analyze the levels of insulin-like growth factors (IGFs), their carrier proteins (
E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. I. Surikova, I. V. Neskubina, Yu. A. Pogorelova, L. K. Trepitaki, N. D. Cheryarina, I. M. Kotieva, M. I. Morozova   +9 more
doaj   +1 more source

Avaliação de parâmetros de cicatrização no cólon de ratos diabéticos sem agressão cirúrgica [PDF]

Acta Cirúrgica Brasileira, 2004
OBJETIVO: Existem poucos estudos na literatura utilizando parâmetros de cicatrização em animais diabéticos antes da agressão cirúrgica e nenhum estudo no colon.
Erika Veruska Paiva Ortolan, César Tadeu Spadella, José Lúcio Martins Machado, Shoiti Kobayasi   +3 more
doaj   +1 more source

How to create an experimental diabetes mellitus model? [PDF]

Pharmacia, 2023
Diabetes is a metabolic disorder characterized by chronic hyperglycemia. Early treatment is very important in terms of preventing diabetes-related late complications with high treatment costs and increasing the patient’s quality of life.
Rabia Edibe Parlar Köprülü
doaj   +3 more sources

DOSE DEPENDENT EFFECT OF GLYCYRRHIZIN ON GLYCAEMIC CONTROL OF TYPE 2 DIABETIC RATS

Khyber Medical University Journal, 2020
OBJECTIVE: To assess the effect of low and high dose of glycyrrhizin on body weight, fasting blood sugar level (FBSL), serum insulin and glycemic indices in high fat diet induced type 2 diabetic rats.
Mufakhara Fatimah, Mahwash Malik, Sidra Mushtaq, Javeria Sarfraz, Zobia Mushtaq, Sadia Chiragh   +5 more
doaj   +1 more source

Heart failure is common in diabetic cats : findings from a retrospective case-controlled study in first-opinionpractice [PDF]

, 2007
Diabetes mellitus is common in the cat and the prevalence of this condition appears to be increasing (Peterson 1998,Rand and Marshall 2004, Rand and others 2004). The prognosis for cats with diabetes mellitus in first opinion practice has received little
Blue Skies Research Grant - RCVS Trust (Funder), Gettinby, G., Little, C.J.L.   +2 more
core   +1 more source

The Effect of Health Education on Knowledge of The Prevention of Diabetes Mellitus

Babali Nursing Research, 2022
Introduction: Diabetes mellitus (DM) is a lifelong disease that cannot be cured permanently, which according to WHO estimates the number of people with diabetes will be the main cause of 7 deaths in 2030.
Dewi Wijayanti
doaj   +1 more source

Pancreatic islet isolation by mechanical-enzymatic separation, stationary collagenase digestion and dextran discontinuous density gradient purification: experimental study in dogs Isolamento das ilhotas pancreáticas pela separação mecânica-enzimática digestão estacionária com colagenase e purificação com gradiente de densidade descontínua de dextran: estudo experimental em cães

Acta Cirúrgica Brasileira, 2002
The prospects for allotransplantation of pancreatic islets in man depend on the development of methods that provide sufficient quantities of pancreatic islets from a single donor, which are capable, when transplanted, of achieve the normalization of ...
Jaques Waisberg, Heloísa Prado Soares, Luís Gustavo Altieri, Osíris Ramaciotti, Manlio Basilio Speranzini   +4 more
doaj   +1 more source