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Experimental Approaches to Diabetes Mellitus
Eurasian Journal of Medicine, 2022 One of the most common health problems today, diabetes is a serious, chronic, and complex disease characterized by high blood glucose levels. Nowadays, experimental diabetes models are being developed to study existing diabetes in depth, to improve diabetes medications, or to develop new medications.
Muhammed Yayla, Damla Binnetoğlu
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Experimental Diabetes Mellitus in Different Animal Models [PDF]
Journal of Diabetes Research, 2016 Animal models have historically played a critical role in the exploration and characterization of disease pathophysiology and target identification and in the evaluation of novel therapeutic agents and treatments in vivo.
Amin Al-awar +8 more
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The latest progression of N6-methyladenosine (m6A) RNA modification in diabetes mellitus and diabetic complications [PDF]
Frontiers in EndocrinologyThe increasing global prevalence of diabetes mellitus and its complications continues to encourage exploration of novel molecular mechanisms for their prevention and treatment.
Guangyang Yin +5 more
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Frontiers in Cell and Developmental Biology, 2020 Liraglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), has been demonstrated to alleviate non-alcoholic fatty liver disease (NAFLD). However, the underlying mechanism has not been fully elucidated.
Yunyun Fang +8 more
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Бюллетень сибирской медицины, 2022 Persistent hyperglycemia resulting from diabetes mellitus causes microvascular lesions and long-term diabetic complications, such as nephropathy.The aim of the study was to analyze the levels of insulin-like growth factors (IGFs), their carrier proteins (
E. M. Frantsiyants +9 more
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Vascular Reactivity in Experimental Diabetes Mellitus [PDF]
Circulation Research, 1964 Vascular reactivity was examined in vessels of the perfused hindquarters of alloxan diabetic and control rats. A significant increase was noted in responsiveness of the diabetic animals to intra-arterial injection of epinephrine, norepinephrine, and synthetic angiotensin.
MICHAEL J. BRODY +2 more
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DOSE DEPENDENT EFFECT OF GLYCYRRHIZIN ON GLYCAEMIC CONTROL OF TYPE 2 DIABETIC RATS
Khyber Medical University Journal, 2020 OBJECTIVE: To assess the effect of low and high dose of glycyrrhizin on body weight, fasting blood sugar level (FBSL), serum insulin and glycemic indices in high fat diet induced type 2 diabetic rats.
Mufakhara Fatimah +5 more
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Avaliação de parâmetros de cicatrização no cólon de ratos diabéticos sem agressão cirúrgica [PDF]
Acta Cirúrgica Brasileira, 2004 OBJETIVO: Existem poucos estudos na literatura utilizando parâmetros de cicatrização em animais diabéticos antes da agressão cirúrgica e nenhum estudo no colon.
Erika Veruska Paiva Ortolan +3 more
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How to create an experimental diabetes mellitus model? [PDF]
Pharmacia, 2023 Diabetes is a metabolic disorder characterized by chronic hyperglycemia. Early treatment is very important in terms of preventing diabetes-related late complications with high treatment costs and increasing the patient’s quality of life.
Rabia Edibe Parlar Köprülü
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Heart failure is common in diabetic cats : findings from a retrospective case-controlled study in first-opinionpractice [PDF]
, 2007 Diabetes mellitus is common in the cat and the prevalence of this condition appears to be increasing (Peterson 1998,Rand and Marshall 2004, Rand and others 2004). The prognosis for cats with diabetes mellitus in first opinion practice has received little
Blue Skies Research Grant - RCVS Trust (Funder) +2 more
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