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Experimental Approaches to Diabetes Mellitus
One of the most common health problems today, diabetes is a serious, chronic, and complex disease characterized by high blood glucose levels. Nowadays, experimental diabetes models are being developed to study existing diabetes in depth, to improve diabetes medications, or to develop new medications.
Muhammed Yayla, Damla Binnetoğlu
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Experimental Diabetes Mellitus in Different Animal Models [PDF]
Animal models have historically played a critical role in the exploration and characterization of disease pathophysiology and target identification and in the evaluation of novel therapeutic agents and treatments in vivo.
Amin Al-awar +8 more
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Vascular Reactivity in Experimental Diabetes Mellitus [PDF]
Vascular reactivity was examined in vessels of the perfused hindquarters of alloxan diabetic and control rats. A significant increase was noted in responsiveness of the diabetic animals to intra-arterial injection of epinephrine, norepinephrine, and synthetic angiotensin.
MICHAEL J. BRODY +2 more
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Avaliamos o efeito da aminoguanidina sobre o estresse oxidativo pulmonar e a estrutura pulmonar em um modelo experimental de diabetes mellitus.
Fabio Cangeri Di Naso +5 more
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The purpose. The features of the restructuring of the lymphoid component of periodontal disease in experimental diabetes mellitus and in the combination with experimental diabetes mellitus with the presence of photopolymer or cement fillings were studied
O. A. Varakuta, O. H. Kushch
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Experimental models of diabetes mellitus [PDF]
Early studies on pancreatectomised dogs confirmed the central role of the pancreas in the homeostasis of glycemia and resulted in the discovery of insulin. Today, hundreds of different animal models are used in experimental studies of diabetes. The aim of this review is to present experimental models of type 1 and type 2 diabetes. In preparing for this
Jelena Pantic +2 more
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Acute and chronic animal models for the evaluation of anti-diabetic agents
Diabetes mellitus is a potentially morbid condition with high prevalence worldwide thus being a major medical concern. Experimental induction of diabetes mellitus in animal models is essential for the advancement of our knowledge and understanding of the
Kumar Suresh +3 more
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Diabetes mellitus has become a serious and growing public health concern. It has high morbidity and mortality because of its complications, such as diabetic nephropathy, diabetic cardiovascular complication, diabetic neuropathy, diabetic retinopathy, and
Jin-Ming Meng +8 more
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Aim. To investigate the content of insulin-like growth factor (IGF)-1, IGF-2, and their transporter proteins IGFBP-1 and IGFBP in the liver of rats with experimental diabetes, Guerin’s carcinoma, and their combination.Materials and methods.
E. M. Frantsiyants +12 more
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O diabetes mellitus é uma desordem endócrino-metabólica caracterizada pela hiperglicemia. O seu impacto no sistema respiratório é caracterizado por alterações funcionais e na troca gasosa.
Luiz Alberto Forgiarini Junior +4 more
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