Results 111 to 120 of about 936,403 (288)

Potensi Ekstrak Rumput Laut Coklat (Sargassumprismaticum) Untuk Meningkatkan Aktivitas Superoksida Dismutase (Sod) Dan Gambaran Histologi Jaringan Hepar Pada Tikus (Rattus Norvegicus) Diabetes Melitus Tipe 1 [PDF]

, 2013
The aim of this research was to investigate the ability of brown seaweed (Sargassum prismaticum) extract that can increase the activity of SOD and improvement of hepar tissue on rats Rattus norvegicus type 1 diabetes mellitus the results of multiple low ...
Aulanni’am, A. (Aulanni’am), Prasetyawan, S. (Sasangka), Sari, A. R. (Ardian)   +2 more
core  

Podocyte RIPK3 Deletion Improves Diabetic Kidney Disease by Attenuating NF‐κB p65 Driven Inflammation

Advanced Science, EarlyView.
Prevention and treatment of diabetic kidney disease (DKD) have become a major global public health challenge. This study shed new light on the underlying pathogenic mechanisms of podocyte injury in DKD and highlights the therapeutic potential of mitigating podocyte injury through inhibition of the RIPK3/NF‐κB p65‐mediated inflammatory response as a ...
Lu'an Li, Jiaying Li, Ruizhao Li, Xingchen Zhao, Yuanhan Chen, Yating Cai, Yan Yang, Weiteng Wang, Siqi Zheng, Li Zhang, Xinling Liang   +10 more
wiley   +1 more source

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

Advanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu, Lin Jing, Yixin Li, Jinxing Zhou, Xiaohui Cui, Sen Li, Shijie Yang, Fangming Kan, Junfeng Du, Wentao Zhong, Sheng Yu, Ning Wang, Xing Jia, Junhui Li, Pan Nie, Zhenzhong Chen, Ying Han, Lingxi Jiang, Xiyun Yan, Hongxia Duan, Baiyong Shen   +20 more
wiley   +1 more source

Type 1 diabetes mellitus: retrospect and prospect

Bulletin of the National Research Centre
Background Type 1 diabetes (T1D) is an autoimmune disease leading to destruction of insulin-producing pancreatic beta cells. Both genetic and environmental factors contribute to pathogenesis. The incidence of T1D is increasing worldwide, with significant
Tamer A. Addissouky, Majeed M. A. Ali, Ibrahim El Tantawy El Sayed, Yuliang Wang   +3 more
doaj   +1 more source

Addressing the Malta National Strategy for Diabetes 2016-2020 research priority areas: A scoping review

Endocrine and Metabolic Science, 2021
Diabetes mellitus is one of the major reasons for morbidity in Malta. A National Diabetes Strategy launched in 2016 identified research priority areas. The aim of this scoping review was to identify and describe the research on these areas.
Roberta Sammut
doaj  

Fetal growth and glycemic control in type 1 diabetes pregnancy [PDF]

, 2004
INTRODUCTION: Conflicting results have been reported with respect to the relationship between direct or indirect measures of glycemic control in mothers with type 1 diabetes and macrosomia.
Campos, MV, Cravo, A, Leitão, P, Lobo, C, Marta, E, Paiva, S, Ruas, L, Sobral, E   +7 more
core  

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

Advanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong, Guangyu Liang, Huimin Yu, Jiaqi Li, Ruohong Wang, Xiaohong Ma, Ziqing Zhou, Yin Zhao, Fei Sun, Xufang Sun   +9 more
wiley   +1 more source

Plasma lipid peroxidation zinc and erythrocyte cu-zn superoxide dismutase enzyme activity in patients with type 2 diabetes mellitus in Gorgan City (South East of the Caspian Sea)

, 2007
The aim of this study was to determine the changes of plasma lipid peroxidation, zinc and erythrocyte Cu-Zn superoxide dismutase activity in patients with type 2 diabetes mellitus and healthy control in Gorgan city.
Marjani, A., Moradi, A., Saeedi, M.
core  

Risk Factors Poor Glycemic Control Among Patients with Type 2 Diabetes Mellitus at the Primary Health Center of Kembiritan Banyuwangi Regency [PDF]

, 2015
Background and purpose: Number of patients with type 2 diabetes mellitus in Kembiritan Primary Health Centerhas increased as many as 160 in 2013 to 215 in 2014.
Purwitaningtyas, R. Y. (Rizki), Putra, I. W. (I), Wirawan, D. N. (D)   +2 more
core  

Advances in Medical Devices for Augmented Acupuncture Therapy

Advanced Science, EarlyView.
Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai, Chenyi Yu, Xinyi Luo, Ningyu Xu, Jicheng Yu, Xiao Ye, Yuqi Zhang, Zhen Gu   +7 more
wiley   +1 more source