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Experimental models of diabetes mellitus [PDF]

Serbian Journal of Experimental and Clinical Research, 2011
Early studies on pancreatectomised dogs confirmed the central role of the pancreas in the homeostasis of glycemia and resulted in the discovery of insulin. Today, hundreds of different animal models are used in experimental studies of diabetes. The aim of this review is to present experimental models of type 1 and type 2 diabetes. In preparing for this
Jelena Pantic, Vladislav Volarevic, Aleksandar Djukic   +2 more
openaire   +1 more source

Reactivity of the lymphoid component of the periodontium using various filing materials against experimental diabetes

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
The purpose. The features of the restructuring of the lymphoid component of periodontal disease in experimental diabetes mellitus and in the combination with experimental diabetes mellitus with the presence of photopolymer or cement fillings were studied
O. A. Varakuta, O. H. Kushch
doaj   +1 more source

Acute and chronic animal models for the evaluation of anti-diabetic agents

Cardiovascular Diabetology, 2012
Diabetes mellitus is a potentially morbid condition with high prevalence worldwide thus being a major medical concern. Experimental induction of diabetes mellitus in animal models is essential for the advancement of our knowledge and understanding of the
Kumar Suresh, Singh Rajeshwar, Vasudeva Neeru, Sharma Sunil   +3 more
doaj   +1 more source

Effects and Mechanisms of Tea for the Prevention and Management of Diabetes Mellitus and Diabetic Complications: An Updated Review

Antioxidants, 2019
Diabetes mellitus has become a serious and growing public health concern. It has high morbidity and mortality because of its complications, such as diabetic nephropathy, diabetic cardiovascular complication, diabetic neuropathy, diabetic retinopathy, and
Jin-Ming Meng, Shi-Yu Cao, Xin-Lin Wei, Ren-You Gan, Yuan-Feng Wang, Shu-Xian Cai, Xiao-Yu Xu, Pang-Zhen Zhang, Hua-Bin Li   +8 more
doaj   +1 more source

Estresse oxidativo e alterações estruturais pulmonares no diabetes mellitus experimental Experimental diabetes mellitus: oxidative stress and changes in lung structure

Jornal Brasileiro de Pneumologia, 2009
O diabetes mellitus é uma desordem endócrino-metabólica caracterizada pela hiperglicemia. O seu impacto no sistema respiratório é caracterizado por alterações funcionais e na troca gasosa.
Luiz Alberto Forgiarini Junior, Nélson Alexandre Kretzmann, Marilene Porawski, Alexandre Simões Dias, Norma Anair Possa Marroni   +4 more
doaj   +1 more source

How to create an experimental diabetes mellitus model? [PDF]

Pharmacia, 2023
Diabetes is a metabolic disorder characterized by chronic hyperglycemia. Early treatment is very important in terms of preventing diabetes-related late complications with high treatment costs and increasing the patient’s quality of life.
Rabia Edibe Parlar Köprülü
doaj   +3 more sources

Insulin-like growth factors and their transporter proteins in the liver of rats with experimental diabetes, adenocarcinoma of the uterine corpus, and their combination

Бюллетень сибирской медицины, 2022
Aim. To investigate the content of insulin-like growth factor (IGF)-1, IGF-2, and their transporter proteins IGFBP-1 and IGFBP in the liver of rats with experimental diabetes, Guerin’s carcinoma, and their combination.Materials and methods.
E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. A. Sheiko, E. I. Surikova, I. V. Neskubina, I. K. Trepitaki, Yu. A. Pogorelova, N. D. Cheryarina, L. A. Nemashkalova, I. M. Kotieva, A. V. Shaposhnikov, M. I. Morozova   +12 more
doaj   +1 more source

Mechanism of changes of peripheral neuromuscular endings of the tongues of rats with experimental streptozotocyn diabetes mellitus

Regulatory Mechanisms in Biosystems, 2017
This paper presents the characteristics of dynamics of morphological changes of neuromuscular endings of the tongues of rats with experimentally induced streptozotocin diabetes mellitus.
M. Luchynskyi, V. Luchinskyi, V. Shcherba, A. Demkovych, Y. Luchinska   +4 more
doaj   +1 more source

Anti-Inflammatory Effects of Melatonin in Rats with Induced Type 2 Diabetes Mellitus

Life, 2022
Introduction: Insulin resistance is associated with a pro-inflammatory state increasing the risk for complications in patients with type 2 diabetes mellitus (T2DM).
Hande Yapislar, Ebru Haciosmanoglu, Turkan Sarioglu, Sevgin Degirmencioglu, Ibrahim Sogut, Michael Poteser, Cem Ekmekcioglu   +6 more
doaj   +1 more source

Auditory Temporal Resolution in Individuals with Diabetes Mellitus Type 2

International Archives of Otorhinolaryngology, 2016
Introduction “Diabetes mellitus is a group of metabolic disorders characterized by elevated blood sugar and abnormalities in insulin secretion and action” (American Diabetes Association).
Rajkishor Mishra, Himanshu Kumar Sanju, Prawin Kumar   +2 more
doaj   +1 more source