Results 111 to 120 of about 1,610,988 (356)

Bright Renoprotective Properties of Metformin Beyond Blood Glucose Regulatory Effects [PDF]

, 2013
Metformin, a biguanide drug, is widely prescribed to treat high blood glucose in individuals with type 2 diabetes mellitus. Type 2 diabetes mellitus is a troubling chronic disease and diabetic nephropathy is one of the most important complications of ...
Ardalan, Mohammadreza., Baradaran, Azar., Mardani, Saeed., Momeni, Ali., Nasri, Hamid., Rafieian-Kopaei, Mahmoud.   +5 more
core  

Persistent hypertriglyceridemia in statin-treated patients with type 2 diabetes mellitus [PDF]

, 2013
Purpose: This paper reports the results of an audit that assessed the prevalence of residual hypertriglyceridemia and the potential need for intensified management among patients with statin-treated type 2 diabetes mellitus (T2DM) in primary care in the ...
Feher, Michael D., Greener, Mark, Munro, Neil   +2 more
core   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Food consumption by degree of food processing and risk of type 2 diabetes mellitus: a prospective cohort analysis of the European Prospective Investigation into Cancer and Nutrition (EPIC)Research in context

The Lancet Regional Health. Europe
Summary: Background: It is unknown whether the association between ultra-processed food (UPF) intake and type 2 diabetes mellitus differs from other degrees of food processing.
Samuel J. Dicken, Christina C. Dahm, Daniel B. Ibsen, Anja Olsen, Anne Tjønneland, Mariem Louati-Hajji, Claire Cadeau, Chloé Marques, Matthias B. Schulze, Franziska Jannasch, Ivan Baldassari, Luca Manfredi, Maria Santucci de Magistris, Maria-Jose Sánchez, Carlota Castro-Espin, Daniel Rodríguez Palacios, Pilar Amiano, Marcela Guevara, Yvonne T. van der Schouw, Jolanda M.A. Boer, W.M. Monique Verschuren, Stephen J. Sharp, Nita G. Forouhi, Nicholas J. Wareham, Eszter P. Vamos, Kiara Chang, Paolo Vineis, Alicia K. Heath, Marc J. Gunter, Geneviève Nicolas, Elisabete Weiderpass, Inge Huybrechts, Rachel L. Batterham   +32 more
doaj   +1 more source

Association of high-sensitive C-reactive protein with advanced stage beta-cell dysfunction and insulin resistance in patients with type 2 diabetes mellitus [PDF]

, 2006
Background: Type 2 diabetes mellitus is associated with increased cardiovascular risk. One laboratory marker for cardiovascular risk assessment is high-sensitivity C-reactive protein (hsCRP).
Balkau, Forst, Haffner, Haffner, Hedblad, Howard, Huupponen, Langenfeld, Maseri, Matthews, Morrow, Nissen, Paice, Pfützner, Pfützner, Pfützner, Pfützner, Pfützner, Pfützner, Pfützner, Ridker, Ridker, Ridker, Ridker, Ridker, Ridker, Riveline, Ross, Saito, Sellmayer, Serrano Rios, Simpson, Willerson, Yudkin   +33 more
core   +1 more source

Type 2 diabetes mellitus and bone [PDF]

Journal of Internal Medicine, 2018
AbstractType 2 diabetes (T2DM) is a rapidly growing public health problem. It is associated with an increased risk of fracture, particularly of the hip, despite normal or high bone mineral density. Longer duration of disease and poor glycaemic control are both associated with higher fracture risk. The factors underlying increased fracture risk have not
openaire   +2 more sources

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

Advanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo, Daniel Lozano, Antonio J. Salinas, María Vallet‐Regí   +3 more
wiley   +1 more source

Early Maladjustment Schemas in Individuals with and without Type 2 Diabetes Mellitus [PDF]

, 2019
Objective. This study explored Early Maladjustment Schemas (EMSs) among individuals with and without type 2 diabetes mellitus and examined potential moderating roles for gender, level of education, and occupation. Methods.
Gholamrezaei, Simin, Khodarahimi, Siamak, Mirdrikvand, Fazlolah, Rahimian Bougar, Mojtaba, Sepahvandi, Mohamad Ali, Shafikhani, Pejman   +5 more
core   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Preventive pharmacotherapy in type 2 diabetes mellitus

Indian Journal of Endocrinology and Metabolism, 2012
Over the last few decades certain demographic changes have been observed worldwide, which have led to an increase in the prevalence of chronic non-communicable diseases.
Neeraj Choudhary, Sanjay Kalra, Ambika Gopalakrishnan Unnikrishnan, T P Ajish   +3 more
doaj   +1 more source