Results 141 to 150 of about 40,578 (245)

Melanoma of the Choroid and Ciliary Body in Children: Remission of Metastatic Melanoma of the Choroid After Treatment With Chemotherapy and Immune Checkpoint Inhibition

open access: yesPediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background Uveal melanoma is the most common malignant primary intraocular tumor in adults, associated with high mortality. Pediatric uveal melanoma generally has a more favorable course. However, when metastasis occurs, therapeutic options are limited.
Pia Tüller   +18 more
wiley   +1 more source

Severe hyperglycaemia associated with prolonged isoflurane anaesthesia in an alpaca (Vicugna pacos)

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract Alpacas possess distinct glucose and insulin regulatory mechanisms compared with other species, often maintaining higher baseline blood glucose as a normal physiological adaptation. Inhalant anaesthetic agents can further disrupt glucose, insulin and potassium homeostasis, particularly during prolonged procedures.
Andrea Basler   +3 more
wiley   +1 more source

The effect of foot reflexology massage on the breathing patterns of children hospitalized with diabetic ketoacidosis [PDF]

open access: yesحیات
Background & Aim: Diabetic ketoacidosis is a serious and potentially life-threatening complication of diabetes mellitus. Exploring non-pharmacological interventions that may support standard care in children with this condition is crucial for improving ...
Faezeh Naghiha   +2 more
doaj  

Effects of Siltuximab Versus Corticosteroids in Preventing COVID−19 Pneumonia Disease Progression: Multicentre, Open‐Label, Randomized Clinical Trial

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT In 2020, COVID‐19 caused a global health crisis, prompting research efforts and accelerating drug development. As part of this response, we conducted a phase 2b, multicentre, open‐label, randomized (1:1) clinical trial to compare the effects of siltuximab versus corticosteroids on disease progression in hospitalized adults with COVID‐19 ...
Lorna Leal   +77 more
wiley   +1 more source

Six‐Year Trends in Real‐World Data Use for Post‐Marketing Surveillance of New Medical Products in Japan

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami   +2 more
wiley   +1 more source

Diabetes management in maternally inherited diabetes and deafness (MIDD): A review and a proposed treatment algorithm

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 826-839, February 2026.
Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry   +2 more
wiley   +1 more source

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