Results 101 to 110 of about 5,358,430 (249)

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD [PDF]

, 2011
Family studies suggest a genetic component to the etiology of chronic kidney disease (CKD) and end stage renal disease (ESRD). Previously, we identified 16 loci for eGFR in genome-wide association studies, but the associations of these single nucleotide ...
Kronenberg, F, Fox, Caroline S., Hoffmann, M.M., Powe, Neil, Hwang, Shih-Jen, Siscovick, D.S. (David), W H Kao, Paulweber, Bernhard, Hwang, SJ, Ravi I Thadhani, Rivadeneira Ramirez, F. (Fernando), Carsten A., Böger, Hoffmann, MM, Huang, C., O'Seaghdha, C.M., Kutalik, Z, Köttgen, A., Hoffmann, Michael M., Coassin, S, Heid, Iris M., Hoffmann, Michael M, H.-Erich Wichmann, Witteman, J., Yang, Q. (Qiong Fang), Powe, N., Jacques S Beckmann, Witteman, Jacqueline, Shlipak, M.G. (Michael), Huang, CM, Rettig, Rainer, null null, Heid, I.M. (Iris), Barbara Kollerits, Haun, M., Coassin, S. (Stefan), Krane, V. (Vera), Teumer, A. (Alexander), Hofman, Bert, Powe, N. (Neil), Haun, M, Kronenberg, F. (Florian), Bochud, Murielle, Kutalik, Zoltan, Haak, Thomas, Wichmann, H.E., Kao, W.H.L. (Wen), Wichmann, H.E. (Heinz Erich), Haak, T., Heid, I.M., Siscovick, D, Kronenberg, Florian, Wanner, C, Bochud, M., Krämer, B.K., Hofman, A., Caroline S. Fox, Bernhard K Krämer, Haun, Margot, Carsten A Böger, Wichmann, H-Erich, Kim, Stuart K., Heid, IM, Wichmann, H.-Erich, Wanner, Christoph, Böger, Carsten A., Gorski, M. (Mathias), Boger, CA, Böger, C.A., Krämer, Bernhard K., Coassin, S., Carsten A. Böger, Fox, C.S., Kollerits, B. (Barbara), Michael M. Hoffmann, Gorski, Mathias, Rivadeneira, Fernando, Heid, Iris M, Li, M., Shlipak, M.G., Coassin, Stefan, Kollerits, Barbara, Haak, T. (Thomas), Kollerits, B, David Siscovick, Man Li, Krämer, Bernhard K, Haak, T, Rettig, R, Thomas Haak, Florian Kronenberg, Coresh, J. (Josef), Abbas Dehghan, Zoltán Kutalik, O'Seaghdha, CM, Li, M, Wichmann, HE, Coresh, Josef, Siscovick, David, O'Seaghdha, Conall M., Hoffmann, M.M. (Michael), Wanner, C., O'Seaghdha, C.M. (Conall), Shlipak, MG, Krane, Vera, Chunmei Huang, Hwang, S.J., Stefan Coassin, Rettig, R. (Rainer), Siscovick, D., Shlipak, Michael G, Teumer, Alexander, Gorski, M., Kronenberg, F., Fox, C.S. (Caroline), Fernando Rivadeneira, Jacqueline Witteman, Huang, Chunmei, Paulweber, B., Thadhani, R.I. (Ravi), W. H. Kao, Neil Powe, Kao, W. H., Shih-Jen Hwang, Uitterlinden, Andre, Conall M O'Seaghdha, Li, M. (Man), Beckmann, J.S. (Jacques), Koettgen, Anna, Paulweber, B, Yang, Qiong, Kottgen, A, Yang, Q, Boes, Eva, Huang, C. (Chunmei), Uitterlinden, André; id_orcid, Köttgen, A. (Anna), Powe, N, Fox, CS, Rivadeneira, F., CKDGen Consortium, Boes, E, Boes, E. (Eva), Yang, Q., Beckmann, Jacques S., Ravi I. Thadhani, Murielle Bochud, Michael M Hoffmann, Conall M. O'Seaghdha, Guo Li, Uitterlinden, A.G. (André), Dehghan, A. (Abbas), Hofman, A. (Albert), Witteman, JCM, Böger, C.A. (Carsten), Albert Hofman, Krämer, B.K. (Bernhard), Iris M Heid, Rettig, R., Michael G Shlipak, Dehghan, Abbas, H-Erich Wichmann, Kao, WH, Kraemer, Bernhard K., Köttgen, Anna, Qiong Yang, Josef Coresh, Bochud, M. (Murielle), Michael G. Shlipak, Dehghan, A., Caroline S Fox, O'Seaghdha, Conall M, Shlipak, Michael G., Teumer, A., Iris M. Heid, Coresh, J, Beckmann, Jacques S, Eva Boes, Bernhard Paulweber, Rainer Rettig, Beckmann, J.S., Kao, W.H., Bochud, M, Teumer, A, Wichmann, Heinz-Erich, Jacques S. Beckmann, Boeger, Carsten A., Haun, M. (Margot), Alexander Teumer, André Uitterlinden, Kollerits, B., Uitterlinden, A., Vera Krane, Krane, V, Anna Köttgen, Kutalik, Z., Bernhard K. Krämer, Kramer, BK, Thadhani, R.I., Krane, V., Margot Haun, Thadhani, Ravi I, Li, Guo, Wanner, C. (Christoph), Paulweber, B. (Bernhard), Böger, Carsten A, Hofman, Albert, Christoph Wanner, Li, Man, Mathias Gorski, Li, G., Witteman, J.C.M. (Jacqueline), Thadhani, RI, Beckmann, JS, Gorski, M, Coresh, J., Kutalik, Z. (Zoltán), Thadhani, Ravi I., Boes, E., Li, G (Guo), Fox, Caroline S, Kao, Wen Hong Linda, CKDGen Consortium, [Study group]   +221 more
core   +2 more sources

Association of ELMO1 polymorphism with risk of Xinjiang Uygur diabetic kidney diseases

Linchuang shenzangbing zazhi, 2017
Objective To study whether the engulfment and cell motility 1gene(ELMO1)polymorphism is associated with a high risk of Xinjiang Uygurdiabetic kidney diseases,analyze the clinical index and biochemical index among the normal controls,simple diabetes and ...
WENG Chang-ya, SONG Xue, ZHANG Hui, DUAN Ya-li, GUO Yu, LU Chen   +5 more
doaj  

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M. Guthridge, Carla Guthridge, Peter Izmirly, Jill P. Buyon, H. Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'Era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

Biomarker for early renal microvascular and diabetic kidney diseases

Renal Failure, 2017
Recognition of early stage of diabetic kidney disease, under common practice using biomarkers, namely microalbuminuria, serum creatinine level above 1 mg/dL and accepted definition of diabetic kidney disease associated with creatinine clearance value ...
Narisa Futrakul, Prasit Futrakul
doaj   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

SARS-CoV-2 receptor networks in diabetic and COVID-19–associated kidney disease

, 2020
COVID-19 morbidity and mortality are increased via unknown mechanisms in patients with diabetes and kidney disease. SARS-CoV-2 uses angiotensin-converting enzyme 2 (ACE2) for entry into host cells.
Chen, Xi, Boppana, Avinash S, Sexton, Jonathan Z, Wang, Yuan, Sohaney, Ryann, Wong, Aaron K, Wobus, Christiane E, Subramanian, Lalita, Hodgin, Jeffrey B, Naik, Abhijit S, Troyanskaya, Olga G, Godfrey, Bradley, Mariani, Laura H, Lienczewski, Chrysta C, Harder, Jennifer L, Hartman, John, Schaub, Jennifer A, Kretzler, Matthias, Menon, Rajasree, Yang, Yingbao, Sealfon, Rachel, Berthier, Celine C, Nelson, Robert G, Theesfeld, Chandra L, Kasson, Peter M, Eddy, Sean, Looker, Helen C, Fermin, Damian, Nair, Viji, Dagenais, Susan L, Luo, Jinghui, Otto, Edgar A   +31 more
core   +1 more source

Vasopressin and Diabetic Kidney Disease [PDF]

Annals of Nutrition and Metabolism, 2018
<b><i>Background:</i></b> Diabetic nephropathy has become the most common cause of chronic kidney disease (CKD). Despite the progress accomplished in therapy, the prevalence of renal disorders remains high. Some modifiable factors driving the increase in incidence of CKD, in diabetes and other settings, might have been ...
openaire   +2 more sources

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

Arthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok, Samantha Morais, William K. Silverstein, Clare L. Atzema, Gregory Choy, Priyanka Chandratre, Ping Li, Jessica Widdifield   +7 more
wiley   +1 more source