Results 111 to 120 of about 5,358,430 (249)

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

39 - Epidemiology of Diabetic Kidney Disease

, 2020
Diabetic kidney disease (DKD), also known as diabetic nephropathy, refers to chronic kidney disease that is caused by diabetes. Although a kidney biopsy is required for a definitive diagnosis, in most cases careful screening of patients with diabetes can
Groop, Per Henrik, Nelson, Robert G, Fornoni, Alessia, Najafian, Behzad   +3 more
core   +1 more source

β2-Adrenergic Receptor Agonists in Diabetic Kidney Disease: Exploring a New Frontier

Biochemistry Research International
Diabetic kidney disease is a major cause of end-stage kidney disease. Various metabolic, hemodynamic, inflammatory, and profibrotic factors secondary to diabetes mellitus result in complex intracellular signaling, which in turn is responsible for the ...
Shreya Hegde, Bharti Chogtu, Rahul Magazine, Ravindra Prabhu   +3 more
doaj   +1 more source

Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease

Nature Communications, 2019
Diabetes is a major cause of kidney disease. Here Kikuchi et al. show that phenol sulfate, a gut microbiota-derived metabolite, is increased in diabetic kidney disease and contributes to the pathology by promoting kidney injury, suggesting phenyl sulfate
Koichi Kikuchi, Daisuke Saigusa, Yoshitomi Kanemitsu, Yotaro Matsumoto, Paxton Thanai, Naoto Suzuki, Koki Mise, Hiroaki Yamaguchi, Tomohiro Nakamura, Kei Asaji, Chikahisa Mukawa, Hiroki Tsukamoto, Toshihiro Sato, Yoshitsugu Oikawa, Tomoyuki Iwasaki, Yuji Oe, Tomoya Tsukimi, Noriko N. Fukuda, Hsin-Jung HO, Fumika Nanto-Hara, Jiro Ogura, Ritsumi Saito, Shizuko Nagao, Yusuke Ohsaki, Satoshi Shimada, Takehiro Suzuki, Takafumi Toyohara, Eikan Mishima, Hisato Shima, Yasutoshi Akiyama, Yukako Akiyama, Mariko Ichijo, Tetsuro Matsuhashi, Akihiro Matsuo, Yoshiaki Ogata, Ching-Chin Yang, Chitose Suzuki, Matthew C. Breeggemann, Jurgen Heymann, Miho Shimizu, Susumu Ogawa, Nobuyuki Takahashi, Takashi Suzuki, Yuji Owada, Shigeo Kure, Nariyasu Mano, Tomoyoshi Soga, Takashi Wada, Jeffrey B. Kopp, Shinji Fukuda, Atsushi Hozawa, Masayuki Yamamoto, Sadayoshi Ito, Jun Wada, Yoshihisa Tomioka, Takaaki Abe   +55 more
doaj   +1 more source

Periodontal Disease with Diabetes or Diabetes Kidney Disease [PDF]

International Journal of Trend in Scientific Research and Development, 2018
diseases such as diabetes and atherosclerosis, cardiovascular diseases, and even chronic kidney disease CKD through low grade systemic inflammation, although no causality can be drawn. CKD is an increasing problem worldwide, and has adverse effects on oral health.
openaire   +1 more source

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

Arthritis Care &Research, EarlyView.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo, Bhavisha Desai, Abiola Oladapo, Nana Kragh, Rebekah Zincavage, Brad Padilla, Naomi Schlesinger   +6 more
wiley   +1 more source

The role of kidney biopsy in deciphering diabetic versus non-diabetic origin of kidney disease among patients with type 2 diabetes mellitus and nephrotic range proteinuria: A retrospective study

Metabolism Open
Background: Diabetes mellitus (DM) is tightly associated with the increased prevalence of diabetic kidney disease (DKD). Nonetheless, severe renal function impairment and/or nephrotic range-proteinuria could also result from non-diabetic renal disease ...
Efstratios Kardalas, Aggeliki Paikopoulou, Dimitra A. Vassiliadi, Dimitris Kounatidis, Natalia G. Vallianou, Christine Vourlakou, Irene Karampela, Maria Dalamaga, Marinella Tzanela, Theodora Stratigou   +9 more
doaj   +1 more source

Chronic Kidney Disease in Diabetes [PDF]

Canadian Journal of Diabetes, 2013
Philip, McFarlane, David, Cherney, Richard E, Gilbert, Peter, Senior   +3 more
openaire   +4 more sources

Elevated liver enzymes is not an impediment to allopurinol dose escalation: an observational cohort study

Arthritis Care &Research, Accepted Article.
Objective Routine liver enzyme monitoring is advocated while on allopurinol but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzymes in gout patients commenced on allopurinol. Methods 150 patients with gout and normal baseline serum aminotransferases initiated on allopurinol were followed ...
May Shuen Tang, Qai Ven Yap, Peter Pak Moon Cheung, Amelia Santosa, Gim Gee Teng   +4 more
wiley   +1 more source

Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]

, 2012
Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
Larkin James R., Guerman Molostvov, Fang Zhang, Naila Rabbani, Thornalley, Paul J., Zhang Fang, Zhang, F. (Fang), Rabbani, Naila, Godfrey Lisa, Molostvov Guerman, James R Larkin, Zehnder Daniel, Paul J. Thornalley, Lisa Godfrey, Zehnder, Daniel, Daniel Zehnder, Godfrey, L. (Lisa), Rabbani Naila, Larkin, James Robert, Thornalley Paul J., Paul J Thornalley, James R. Larkin, Molostvov, Guerman   +22 more
core   +2 more sources