Randomized multicentre pilot study of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: United Kingdom Heart and Renal Protection (HARP)- III—rationale, trial design and baseline data [PDF]
, 2016 BACKGROUND: Patients with chronic kidney disease (CKD) are at risk of progression to end-stage renal disease and cardiovascular disease. Data from other populations and animal experiments suggest that neprilysin inhibition (which augments the ...
Baigent, C. +23 more
core +4 more sources
Serum Ceruloplasmin Level as a Predictor for the Progression of Diabetic Nephropathy in Korean Men with Type 2 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2015 BackgroundOxidative stress is known to be associated with progression of diabetic kidney disease. Ceruloplasmin acts as a pro-oxidant under conditions of severe oxidative stress.
Min Jung Lee +6 more
doaj +1 more source
Two-Year Changes in Diabetic Kidney Disease Phenotype and the Risk of Heart Failure: A Nationwide Population-Based Study in Korea [PDF]
Diabetes & Metabolism Journal, 2023 Background Diabetic kidney disease (DKD) is a risk factor for hospitalization for heart failure (HHF). DKD could be classified into four phenotypes by estimated glomerular filtration rate (eGFR, normal vs. low) and proteinuria (PU, negative vs. positive).
Seung Eun Lee +4 more
doaj +1 more source
Associations of Plasma Glucagon Levels with Estimated Glomerular Filtration Rate, Albuminuria and Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2021 Background Type 2 diabetes mellitus (T2DM) is characterized by elevated fasting glucagon and impaired suppression of postprandial glucagon secretion, which may participate in diabetic complications.
Hua-Xing Huang +10 more
doaj +1 more source
Nondiabetic kidney diseases in type 2 diabetic patients
Kidney Research and Clinical Practice, 2013 Background: The aim of this study was to evaluate the clinical characteristics of nondiabetic nephropathy in type 2 diabetes mellitus patients and to find a clinical significance of renal biopsy and immunosuppressive treatment in such a patient. Methods:
Ye Jin Kim +11 more
doaj +1 more source
Short-Term Effects of Beraprost Sodium on the Markers for Cardiovascular Risk Prediction in Type 2 Diabetic Patients with Microalbuminuria [PDF]
Endocrinology and Metabolism, 2019 BackgroundTo evaluate the changes in cardiovascular risk markers including pulse wave velocity (PWV), microalbuminuria, inflammatory cytokines, and adhesion molecules after treatment with beraprost sodium (BPS) in patients with diabetic nephropathy ...
Yun Mi Choi +4 more
doaj +1 more source
Dietary patterns for adults with chronic kidney disease [PDF]
, 2015 This is the protocol for a review and there is no abstract. The objectives are as follows: This review will evaluate the benefits and harms of dietary patterns among adults with CKD (any stage including people with end-stage kidney disease (ESKD) treated
Campbell, Katrina Louise +8 more
core +1 more source
Morphological pattern of non-diabetic nephropathy in type 2 diabetes mellitus patients
Український Журнал Нефрології та Діалізу, 2022 . The aim of this study was to evaluate the contribution of kidney biopsy performed with an appropriate indication to diagnosis and treatment in diabetic patients with nephropathy.
Meral Mese +2 more
doaj +1 more source
Chemokine receptor CCR1: A new target for progressive kidney disease [PDF]
, 2005 Infiltrating leukocytes are thought to contribute to the progression of kidney disease. Locally produced chemokines guide circulating leukocytes into the kidney, which renders therapeutic blockade of respective chemokine receptors on the leukocyte ...
Anders, Hans-Joachim, Ninichuk, Volha
core +1 more source
A transgenic mouse model for studying the role of the parathyroid hormone-related protein system in renal injury [PDF]
, 2010 Parathyroid hormone- (PTH-) related protein (PTHrP) and its receptor, the PTH1 receptor (PTH1R), are widely expressed in the kidney, where PTHrP exerts a modulatory action on renal function.
Arribas, Ignacio +5 more
core +5 more sources