Results 11 to 20 of about 683,288 (403)

The Effect of Angiotensin-Converting-Enzyme Inhibition on Diabetic Nephropathy [PDF]

open access: bronzeNew England Journal of Medicine, 1993
BACKGROUND Renal function declines progressively in patients who have diabetic nephropathy, and the decline may be slowed by antihypertensive drugs. The purpose of this study was to determine whether captopril has kidney-protecting properties independent
Edmund J. Lewis   +3 more
openalex   +2 more sources

Supervised Learning Models for Early Detection of Albuminuria Risk in Type-2 Diabetes Mellitus Patients [PDF]

open access: yes2023 10th International Conference on Advanced Informatics: Concept, Theory, and Application (ICAICTA), Lombok, Indonesia, 2023, pp. 1-6, 2023
Diabetes, especially T2DM, continues to be a significant health problem. One of the major concerns associated with diabetes is the development of its complications. Diabetic nephropathy, one of the chronic complication of diabetes, adversely affects the kidneys, leading to kidney damage.
arxiv   +1 more source

Long-term statins administration exacerbates diabetic nephropathy via ectopic fat deposition in diabetic mice

open access: yesNature Communications, 2023
Statins play an important role in the treatment of diabetic nephropathy. Increasing attention has been given to the relationship between statins and insulin resistance, but many randomized controlled trials confirm that the therapeutic effects of statins
Tong-sheng Huang   +10 more
semanticscholar   +1 more source

Adiponectin for the treatment of diabetic nephropathy [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2019
The metabolic burden caused by hyperglycemia can result in direct and immediate metabolic injuries, such as oxidative stress and tissue inflammation, in the kidney.
Jun Young Lee   +4 more
doaj   +1 more source

Current findings of kidney biopsy including nephropathy associated with hypertension and diabetes mellitus in Korea [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2020
Background/Aims This study aimed to investigate long-term temporal trends and outcomes of biopsy-proven kidney diseases in a multicenter kidney biopsy cohort, focusing on hypertension and diabetes, the leading causes of end-stage kidney disease (ESKD ...
Kipyo Kim   +5 more
doaj   +1 more source

Mechanistic Pathogenesis of Endothelial Dysfunction in Diabetic Nephropathy and Retinopathy

open access: yesFrontiers in Endocrinology, 2022
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of diabetes. Microvascular endothelial cells are thought to be the major targets of hyperglycemic injury.
Jing Yang, Zhangsuo Liu
semanticscholar   +1 more source

Diabetic Nephropathy [PDF]

open access: yesDiabetes Care, 2005
Perspectives on the News commentaries are part of a free monthly CME activity. The Mount Sinai School of Medicine, New York, New York, designates this activity for 2.0 AMA PRA Category 1 credits. If you wish to participate, review this article and visit www.diabetes.procampus.net to complete a posttest and receive a certificate.
openaire   +9 more sources

Diabetic Nephropathy: Challenges in Pathogenesis, Diagnosis, and Treatment

open access: yesBioMed Research International, 2021
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide. Chronic hyperglycemia and high blood pressure are the main risk factors for the development of DN.
Nur Samsu
semanticscholar   +1 more source

Serum Ceruloplasmin Level as a Predictor for the Progression of Diabetic Nephropathy in Korean Men with Type 2 Diabetes Mellitus [PDF]

open access: yesDiabetes & Metabolism Journal, 2015
BackgroundOxidative stress is known to be associated with progression of diabetic kidney disease. Ceruloplasmin acts as a pro-oxidant under conditions of severe oxidative stress.
Min Jung Lee   +6 more
doaj   +1 more source

Pathophysiology of mesangial expansion in diabetic nephropathy: mesangial structure, glomerular biomechanics, and biochemical signaling and regulation

open access: yesJournal of Biological Engineering, 2022
Diabetic nephropathy, a kidney complication arising from diabetes, is the leading cause of death in diabetic patients. Unabated, the growing epidemic of diabetes is increasing instances of diabetic nephropathy.
H. Y. Thomas, Ashlee N. Ford Versypt
semanticscholar   +1 more source

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