Results 191 to 200 of about 683,288 (403)

Angiogenesis as a Therapeutic Target of (Poly)phenols: Tackling Cancer and Vascular‐Related Complications

Molecular Nutrition &Food Research, EarlyView.
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez, Antonio Vico‐Padilla, Claus Schneider, Juan Carlos Espín, Antonio González‐Sarrías, Juan Antonio Giménez‐Bastida   +5 more
wiley   +1 more source

For those intolerant to ACE inhibitors and ARBs, what is the best therapy for reducing the risk of diabetic nephropathy? [PDF]

, 2005
Angiotensin-converting enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) are the first-line agents for reducing the risk of diabetic nephropathy.
Penmetsa, Santhi, Simmons, Michael
core  

A pathway toward clinical translation of hyperpolarized [1,4‐13C2,2,3‐d2]fumarate as an imaging biomarker for early cellular necrosis in vivo

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose The detection of hyperpolarized carbon‐13 (HP 13C)‐fumarate conversion to 13C‐malate using 13C‐MRSI is a biomarker for early detection of cellular necrosis. Here, we describe the translation of HP 13C‐fumarate as a novel human imaging agent, including the evaluation of biocompatibility and scaling up of the hyperpolarization methods ...
Jonathan R. Birchall, Pascal Wodtke, Ashley Grimmer, Esben S. S. Hansen, Lotte B. Bertelsen, Nikolaj Bøgh, Marta Wylot, Maria J. Zamora‐Morales, Otso Arponen, Ines Horvat‐Menih, Elizabeth C. Latimer, Fung Tan, Evita Pappa, Johann Graggaber, Joseph Cheriyan, Kelly Holmes, Matthew J. Locke, Helen Sladen, Joan Boren, Mikko I. Kettunen, Anita Chhabra, Ian B. Wilkinson, Christoffer Laustsen, Kevin Brindle, Mary A. McLean, Ferdia A. Gallagher   +25 more
wiley   +1 more source

Chronic Kidney Disease – Where Next? : Predicting Outcomes And Planning Care Pathways [PDF]

, 2014
Peer reviewedPublisher ...
Black, Corri, Fluck, Nicholas, Marks, Angharad   +2 more
core   +1 more source

Analysis on related risk factors for cardiocerebral vascular diseases in patients with diabetic kidney disease

Linchuang shenzangbing zazhi, 2019
Objective To investigate the epidemiology and related risk factors for cardiocerebral vascular diseases in patients with diabetic kidney diseases（DKD）.Methods A total of 800 patients with DKD hospitalized in Chengyang District People’s Hospital of ...
ZHANG Zhi-xu, GAO Ai-qing, RAO Xiao-pang
doaj  

Surgical Outcomes Comparison of Spontaneous Middle Cranial Fossa Cerebrospinal Fluid Leaks: Systematic Review and Meta‐analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Spontaneous cerebrospinal fluid (sCSF) leaks of lateral skull base have little consensus on optimal management. We synthesized and evaluated current literature via systematic and meta‐analysis to compare the success rates and complications of the different surgical techniques for middle cranial fossa (MCF) sCSF leak repair.
Dimitrios Spinos, Panagiotis Varoutis, Georgios Geropoulos, Georgios Vavoulis, Georgios Georgountzos, Nina Rafailia Karela, Manthia Papageorgakopoulou, Kyriacos Evangelou, Jameel Muzaffar, Wai Sum Cho   +9 more
wiley   +1 more source

BMP signalling in colorectal cancer: losing the yin to WNTs yang

The Journal of Pathology, EarlyView.
Abstract Colorectal cancer (CRC) is the third most common form of cancer globally, and arises from the hyperproliferation of epithelial cells in the intestine. The architecture and maintenance of these cells is governed by two major signalling pathways working in a counter‐gradient: the stem cell WNT signalling pathway, and the prodifferentiation bone ...
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Contrasting effects of enalapril and metoprolol on proteinuria in diabetic nephropathy. [PDF]

, 1990
S Björck, H. Mulec, Svend Aage Johnsen, G. Nyberg, Mattias Aurell   +4 more
openalex   +1 more source

The Omics‐Driven Machine Learning Path to Cost‐Effective Precision Medicine in Chronic Kidney Disease

PROTEOMICS, EarlyView.
ABSTRACT Chronic kidney disease (CKD) poses a significant and growing global health challenge, making early detection and slowing disease progression essential for improving patient outcomes. Traditional diagnostic methods such as glomerular filtration rate and proteinuria are insufficient to capture the complexity of CKD.
Marta B. Lopes, Roberta Coletti, Flore Duranton, Griet Glorieux, Mayra Alejandra Jaimes Campos, Julie Klein, Matthias Ley, Paul Perco, Alexia Sampri, Aviad Tur‐Sinai   +9 more
wiley   +1 more source

Investigation of the Urinary Peptidome to Unravel Collagen Degradation in Health and Kidney Disease

PROTEOMICS, EarlyView.
ABSTRACT Naturally occurring fragments of collagen type I alpha 1 chain (COL1A1) have been previously associated with chronic kidney disease (CKD), with some fragments showing positive and others negative associations. Using urinary peptidome data from healthy individuals (n = 1131) and CKD patients (n = 5585) this aspect was investigated in detail ...
Ioanna K. Mina, Luis F. Iglesias‐Martinez, Matthias Ley, Lucas Fillinger, Paul Perco, Justyna Siwy, Harald Mischak, Vera Jankowski   +7 more
wiley   +1 more source