Results 91 to 100 of about 753,615 (353)

Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy.

Journal of Clinical Investigation, 2016
The regulatory roles of long noncoding RNAs (lncRNAs) in transcriptional coactivators are still largely unknown. Here, we have shown that the peroxisome proliferator-activated receptor γ (PPARγ) coactivator α (PGC-1α, encoded by Ppargc1a) is functionally
Jianyin Long, Shawn S. Badal, Z. Ye, Yin Wang, Bernard A Ayanga, D. Galvan, Nathanael H Green, B. Chang, P. Overbeek, Farhad R. Danesh   +9 more
semanticscholar   +1 more source

Piper auritum (Kunth) Fungal Endophytes: A Source of Metabolites to Inhibit the Formation of Advanced Glycation End Products

Chemistry &Biodiversity, EarlyView.
Endophytic fungi of P. auritum were evaluated for their ability to produce inhibitors of formation of advanced glycation end products (AGEs). Neopestalotiopsis sp. H2 and Diaporthe sp. H5 extracts were the most active. So, we performed their chemical profiling by untargeted and phenolics‐targeted metabolomic approaches to identify the potential ...
Lory Sthephany Rochín‐Hernández, José Antonio Guerrero‐Analco, Juan Luis Monribot‐Villanueva, Luis Bernardo Flores‐Cotera   +3 more
wiley   +1 more source

Diabetic nephropathy and hypertension in diabetes patients of sub-Saharan countries: a systematic review and meta-analysis

BMC Research Notes, 2018
This meta-analysis was undertaken to estimate the prevalence of diabetic nephropathy and its association with hypertension in diabetics of sub-Saharan African countries. A total of 27 studies were included for the meta-analysis.
Fasil Wagnew, Setegn Eshetie, G. Kibret, Abriham Zegeye, Getenet Dessie, H. Mulugeta, Amanuel Alemu   +6 more
semanticscholar   +1 more source

Antioxidants and Antidiabetic Potential of Polyphenolic Fractions and Crude Extracts of Rhus typhina Fruit, Punica granatum L. Peel, and Terminalia catappa L. Leaves: In Vitro and In Vivo Evaluation

Chemistry &Biodiversity, EarlyView.
This graphical abstract represents the extraction, characterization, and biological evaluation of bioactive compounds derived from specific plant sources. The top section illustrates Rhus coriaria (sumac) fruit, Punica granatum (pomegranate) peel and Terminalia catappa (Indian almond) leaves', which are known for their rich phytochemical composition ...
Mudassir Nazir, Muhammad Abdul Haq, Syed Arsalan Ali, Syed Muhammad Ghufran Saeed, Muhammad Ali Ajmal, Muhammad Nisar, Taseer Ahmed Khan, Alexandros Tsoupras, Shahina Naz   +8 more
wiley   +1 more source

SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy

Journal of Biological Chemistry, 2017
There is very limited human renal sodium gradient-dependent glucose transporter protein (SGLT2) mRNA and protein expression data reported in the literature.
Xiaoxin X. Wang, Jonathan Levi, Yuhuan Luo, K. Myakala, M. Herman-Edelstein, L. Qiu, Dong Wang, Yingqiong Peng, A. Grenz, S. Lucia, E. Dobrinskikh, V. D’Agati, H. Koepsell, J. Kopp, A. Rosenberg, M. Levi   +15 more
semanticscholar   +1 more source

Intravascular Lithotripsy for Calcific Coronary Bifurcations: Procedural Success and 1‐Year Clinical Outcomes

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Intravascular lithotripsy (IVL) has emerged as a promising treatment for heavily calcified coronary lesions. However, evidence regarding its effectiveness in calcific bifurcation lesions remains limited. Objective We aimed to evaluate the technical success and 1‐year clinical outcomes of IVL in calcified coronary bifurcation lesions.
Federico Oliveri, Giulia D'Acunto, Martijn. J.H. van Oort, Akshay Phagu, Ibtihal Al Amri, Brian O. Bingen, Valeria Paradies, Gianluca Mincione, Bimmer E. Claessen, Aukelien C. Dimitriu‐Leen, Joelle Kefer, Hany Girgis, Tessel Vossenberg, Frank Van der Kley, J. Wouter Jukema, Josè M. Montero‐Cabezas   +15 more
wiley   +1 more source

Age at onset of type 1 diabetes between puberty and 30 years old is associated with increased diabetic nephropathy risk

Scientific Reports
Diabetic nephropathy is a critical complication of patients with type 1 diabetes, while epidemiological studies were scarce among Asian countries.
Yen-Bo Lin, Taiwan Diabetes Registry Study Group, Tien-Jyun Chang   +2 more
doaj   +1 more source

Classification and Differential Diagnosis of Diabetic Nephropathy

Journal of Diabetes Research, 2017
Diabetic nephropathy (DN) is a major cause of end-stage renal disease throughout the world in both developed and developing countries. This review briefly introduces the characteristic pathological changes of DN and Tervaert pathological classification ...
Chenyang Qi, Xing Mao, Zhigang Zhang, Huijuan Wu   +3 more
semanticscholar   +1 more source

Premature Mortality in Patients With Anorexia Nervosa: A Matched Cohort Study of Cause of Death

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To determine the extent to which anorexia nervosa is associated with premature mortality. Method We carried out a matched cohort study of 7332 male and female patients with anorexia nervosa and 73,215 patient controls who were admitted between 1989 and 2023 in hospital centers of Quebec, Canada. We tracked the patients longitudinally
Nathalie Auger, Mimi Israël, Howard Steiger, Nancy Low, Nicholas Chadi, Émilie Brousseau, Aimina Ayoub, Gabriel Côté‐Corriveau   +7 more
wiley   +1 more source

Immunoglobulin heavy constant gamma 1 silencing decreases tonicity‐responsive enhancer‐binding protein expression to alleviate diabetic nephropathy

Journal of Diabetes Investigation
Aims/Introduction The molecular mechanisms of diabetic nephropathy (DN) are poorly identified. However, the advantage of an increasing amount on microarray data of diabetic nephropathy intrigued us to explore the mechanisms based on bioinformatics ...
Qibo Hu, Qingxiao Yang, Hang Gao, Jing Tian, Guanghua Che   +4 more
doaj   +1 more source