Results 101 to 110 of about 111,907 (307)

A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes.

PLoS ONE, 2018
To explore novel genetic loci for diabetic nephropathy, we performed genome-wide association studies (GWAS) for diabetic nephropathy in Japanese patients with type 2 diabetes. We analyzed the association of 5,768,242 single nucleotide polymorphisms (SNPs)
Makiko Taira, Minako Imamura, Atsushi Takahashi, Yoichiro Kamatani, Toshimasa Yamauchi, Shin-Ichi Araki, Nobue Tanaka, Natalie R van Zuydam, Emma Ahlqvist, Masao Toyoda, Tomoya Umezono, Koichi Kawai, Masahito Imanishi, Hirotaka Watada, Daisuke Suzuki, Hiroshi Maegawa, Tetsuya Babazono, Kohei Kaku, Ryuzo Kawamori, SUMMIT Consortium, Leif C Groop, Mark I McCarthy, Takashi Kadowaki, Shiro Maeda   +23 more
doaj   +1 more source

Pathogenesis and Treatment of Chronic Kidney Disease: A Review of Our Recent Basic and Clinical Data

Kidney & Blood Pressure Research, 2014
Chronic kidney disease (CKD) is a worldwide public health problem that affects millions of people from all racial and ethnic groups. At end of 2013, over 300,000 Japanese patients had maintenance dialysis therapy (JSDT). In Japan, the major causes of end
Yasuhiko Tomino
doaj   +1 more source

Mechanism of hypertension in diabetic nephropathy

, 2014
High prevalence of hypertension is observed in diabetic patients of both the types. Diabetic nephropathy is one of the major reason for high morbidity, mortality and financial burden in such hypertensive diabetic patients.
Nazar Chaudhary Muhammad Junaid
core  

Diabetic alteration versus postnatal maturation of rat kidney glycoconjugates — comparative detection by lectin probes

, 2013
A panel of ten lectins with different carbohydrate specificities, including three original lectin preparations (MPFA, LABA, and LVA), was used for the investigation of rat kidney glycoconjugate remodeling during postnatal morphogenesis, and the findings ...
Ambarova, Natalya; Department of Histology and Embryology, Lviv National, Medical University, Lviv, Ukraine, Lutsyk, Alexander; Department of Histology and Embryology, Lviv National, Medical University, Lviv, Ukraine, Antonyuk, Volodymyr; Department of Histology and Embryology, Lviv National, Medical University, Lviv, Ukraine; Institute of Cell Biology, National Academy of Sciences of Ukraine, Lviv, Ukraine   +2 more
core   +1 more source

Evaluation of the zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles [PDF]

, 2012
Representative animal models for diabetes-associated vascular complications are extremely relevant in assessing potential therapeutic drugs. While several rodent models for type 2 diabetes (T2D) are available, their relevance in recapitulating renal and ...
Joachim Jankowski, Antonia Vlahou (114470), Vlahou Antonia, Joachim Jankowski (114466), Ariela Benigni (114455), Kossida Sophia, Siwy, Justyna, Mullen, Wiliam, Bernd Mayer (32896), Perco, Paul, Perco, P., Wiliam Mullen (114460), Mischak Harald, Benigni, A., Carlamaria Zoja (114447), Mischak, H., Harald Mischak (103627), Sophia Kossida (113366), Benigni, Ariela, Bernd Mayer, Julie Klein, Justyna Siwy (103595), Klein Julie, Jankowski, J., Justyna Siwy, Kossida, Sophia, Mischak, Harald, Ferdinand H Bahlmann, Vlahou, Antonia, Stevens, Robert, Mayer, B., Zoja, C., Ferdinand H. Bahlmann (114474), Ariela Benigni, Benigni Ariela, Stevens Robert, Mayer Bernd, Kossida, S., Klein, Julie, Wiliam Mullen, Siwy, J., Bahlmann Ferdinand H., Paul Perco (32894), Jankowski, Joachim, Antonia Vlahou, Carlamaria Zoja, Sophia Kossida, Siwy Justyna, Stevens, R., Mullen Wiliam, Mullen, W., Robert Stevens, Zoja, Carlamaria, Perco Paul, Paul Perco, Bahlmann, F.H., Mayer, Bernd, Vlahou, A., Harald Mischak, Klein, J., Robert Stevens (18678), Julie Klein (114451), Bahlmann, Ferdinand H., Zoja Carlamaria, Jankowski Joachim   +64 more
core   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Age at onset of type 1 diabetes between puberty and 30 years old is associated with increased diabetic nephropathy risk

Scientific Reports
Diabetic nephropathy is a critical complication of patients with type 1 diabetes, while epidemiological studies were scarce among Asian countries.
Yen-Bo Lin, Taiwan Diabetes Registry Study Group, Tien-Jyun Chang   +2 more
doaj   +1 more source

Ethnic variations in the prevalence of diabetic retinopathy in people with diabetes attending screening in the United Kingdom (DRIVE UK). [PDF]

, 2012
AIMS: To compare the prevalence of diabetic retinopathy (DR) in people of various ethnic groups with diabetes in the United Kingdom (UK). METHODS: The Diabetic Retinopathy In Various Ethnic groups in UK (DRIVE UK) Study is a cross-sectional study on the ...
Gulliford Martin C., Hiten Dodhia, Gupta Bhaskar, Sobha Sivaprasad, Evans Jennifer R., Jennifer R Evans, Evans, Jennifer R., Mohamed Moin, Moin Mohamed, Dinesh Nagi, Sivaprasad, Sobha, Nagi Dinesh, Evans, Jennifer R, Dodhia Hiten, Gulliford, Martin C., Bhaskar Gupta, Gulliford, Martin C, Dodhia, Hiten, Sivaprasad Sobha, Gupta, Bhaskar, Martin C Gulliford, Mohamed, Moin, Nagi, Dinesh   +22 more
core   +1 more source

A Study on Predicting Split Renal Function Using Renal Blood Flow Weighted Estimated Glomerular Filtration Rate From Arterial Spin Labeling MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Traditional methods for evaluating split renal function, including contrast‐enhanced CT and radionuclide imaging, have limitations related to ionizing radiation or potentially nephrotoxic contrast agents. Purpose To investigate the value of renal blood flow (RBF)‐weighted estimated glomerular filtration rate (eGFR) derived from ...
Zhiyong Lin, Yuxi Li, Rui Wang, Wei Li, Jinxia Zhu, Bernd Kuehn, Jianxing Qiu, Jianping Li   +7 more
wiley   +1 more source

Nondiabetic kidney diseases in type 2 diabetic patients

Kidney Research and Clinical Practice, 2013
Background: The aim of this study was to evaluate the clinical characteristics of nondiabetic nephropathy in type 2 diabetes mellitus patients and to find a clinical significance of renal biopsy and immunosuppressive treatment in such a patient. Methods:
Ye Jin Kim, Yoo Hyung Kim, Ki Dae Kim, Kang Ryun Moon, Jae Ho Park, Bo Mi Park, Hyewon Ryu, Dae Eun Choi, Ki Ryang Na, Kwang Sun Suh, Kang Wook Lee, Young Tai Shin   +11 more
doaj   +1 more source