Results 101 to 110 of about 112,312 (307)

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Icariside II ameliorates diabetic nephropathy in streptozotocin-induced diabetic rats [PDF]

, 2015
Wenjie Tian,1,2,* Hongen Lei,1,* Ruili Guan,1 Yongde Xu,1 Huixi Li,1 Lin Wang,1 Bicheng Yang,1 Zhezhu Gao,1 Zhongcheng Xin1 1Andrology Center, Peking University First Hospital, Peking University, Beijing, 2Department of Urology, The Second Hospital of ...
Li H, Tian W, Lei H, Gao Z, Yang B, Guan R, Xin Z, Xu Y, Wang L   +8 more
core  

Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.
Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner, Antje Augstein, Mahmoud Abdellatif, André Lourenço, Adelino Leite‐Moreira, Inês Falcão‐Pires, Sarah Werner, Holger Thiele, Simon Sedej, Antje Schauer, Volker Adams   +10 more
wiley   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Nephropathy in Diabetes [PDF]

Experimental and Clinical Endocrinology & Diabetes, 2021
Ludwig, Merker, Bernd-Walter, Bautsch, Thomas, Ebert, Martina, Guthoff, Berend, Isermann   +4 more
openaire   +2 more sources

Diabetic Retinopathy in Primary Healthcare in a Brazilian Municipality: A Cross‐Sectional Study Using Teleophthalmology

Health Care Science, EarlyView.
The prevalence of diabetic retinopathy was estimated to be 28.3% (95% CI 21.1–35.4), with most of the cases corresponding to mild non‐proliferative diabetic retinopathy. ABSTRACT Background Diabetic retinopathy is a complication of diabetes and the leading cause of irreversible blindness in people of working age.
Lorrana Luysse dos Anjos Assis, Fernando Korn Malerbi, Rosiane Chiaroti, Lívia Maria Ferrante Vizzotto Consoli, Vanessa Patrícia Pereira Motozo, Francisco Barbosa‐Junior, Rinaldo Eduardo Machado de Oliveira   +6 more
wiley   +1 more source

Effects of N-acetyl cysteine on serum lipoprotein (a) and proteinuria in type 2 diabetic patients [PDF]

, 2013
Background: About 30-40 of diabetic patients who developed nephropathy have lipoprotein disorders, especially lipoprotein a Lp(a), which is related to atherosclerosis.
Forouzan Ganji, Ganji, F., Rouhi, H., Rouhi-Boroujeni, H., Hamid Rouhi   +4 more
core   +1 more source

Immunoglobulin heavy constant gamma 1 silencing decreases tonicity‐responsive enhancer‐binding protein expression to alleviate diabetic nephropathy

Journal of Diabetes Investigation
Aims/Introduction The molecular mechanisms of diabetic nephropathy (DN) are poorly identified. However, the advantage of an increasing amount on microarray data of diabetic nephropathy intrigued us to explore the mechanisms based on bioinformatics ...
Qibo Hu, Qingxiao Yang, Hang Gao, Jing Tian, Guanghua Che   +4 more
doaj   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Evaluation of the zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles [PDF]

, 2012
Representative animal models for diabetes-associated vascular complications are extremely relevant in assessing potential therapeutic drugs. While several rodent models for type 2 diabetes (T2D) are available, their relevance in recapitulating renal and ...
Joachim Jankowski, Antonia Vlahou (114470), Vlahou Antonia, Joachim Jankowski (114466), Ariela Benigni (114455), Kossida Sophia, Siwy, Justyna, Mullen, Wiliam, Bernd Mayer (32896), Perco, Paul, Perco, P., Wiliam Mullen (114460), Mischak Harald, Benigni, A., Carlamaria Zoja (114447), Mischak, H., Harald Mischak (103627), Sophia Kossida (113366), Benigni, Ariela, Bernd Mayer, Julie Klein, Justyna Siwy (103595), Klein Julie, Jankowski, J., Justyna Siwy, Kossida, Sophia, Mischak, Harald, Ferdinand H Bahlmann, Vlahou, Antonia, Stevens, Robert, Mayer, B., Zoja, C., Ferdinand H. Bahlmann (114474), Ariela Benigni, Benigni Ariela, Stevens Robert, Mayer Bernd, Kossida, S., Klein, Julie, Wiliam Mullen, Siwy, J., Bahlmann Ferdinand H., Paul Perco (32894), Jankowski, Joachim, Antonia Vlahou, Carlamaria Zoja, Sophia Kossida, Siwy Justyna, Stevens, R., Mullen Wiliam, Mullen, W., Robert Stevens, Zoja, Carlamaria, Perco Paul, Paul Perco, Bahlmann, F.H., Mayer, Bernd, Vlahou, A., Harald Mischak, Klein, J., Robert Stevens (18678), Julie Klein (114451), Bahlmann, Ferdinand H., Zoja Carlamaria, Jankowski Joachim   +64 more
core   +1 more source