Results 111 to 120 of about 845,031 (279)

Angiotensin type-2 (AT-2)-receptor activation reduces renal fibrosis in cyclosporine nephropathy: evidence for blood-pressure independent effect [PDF]

, 2016
Compound 21 (C21), selective agonist of AT2 receptors, shows antinflammatory effects in hypertension and nephroprotection in diabetes. The aim of this study was to evaluate the effects of C21 in cyclosporine nephropathy, which is characterized mainly by ...
Carletti, R, Castoldi, G, DI GIOIA, Cira Rosaria Tiziana, Roma, F, Stella, A., Zerbini, G   +5 more
core   +1 more source

Research Progress on Mechanism of Podocyte Depletion in Diabetic Nephropathy

Journal of Diabetes Research, 2017
Diabetic nephropathy (DN) together with glomerular hyperfiltration has been implicated in the development of diabetic microangiopathy in the initial stage of diabetic diseases.
Haoran Dai, Qingquan Liu, Baoli Liu
semanticscholar   +1 more source

Elevated hemoglobin glycation index identify non-diabetic individuals at increased risk of kidney dysfunction [PDF]

, 2017
Hemoglobin glycation index (HGI), calculated as the difference between the observed value of HbA1 and the predicted HbA1c based on plasma glucose concentration, is a measure of the individual tendency toward non-enzymatic hemoglobin glycation which has ...
Andreozzi, F, Fiorentino, Tv, Marini, Ma, Perticone, F, Sciacqua, A, Sesti, G, Succurro, E   +6 more
core   +2 more sources

Inflammation in Diabetic Nephropathy

Mediators of Inflammation, 2012
Diabetic nephropathy is the leading cause of end-stage kidney disease worldwide but current treatments remain suboptimal. This review examines the evidence for inflammation in the development and progression of diabetic nephropathy in both experimental and human diabetes, and provides an update on recent novel experimental approaches targeting ...
Andy K. H. Lim, Gregory H. Tesch
openaire   +4 more sources

SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy

Journal of Biological Chemistry, 2017
There is very limited human renal sodium gradient-dependent glucose transporter protein (SGLT2) mRNA and protein expression data reported in the literature.
Xiaoxin X. Wang, Jonathan Levi, Yuhuan Luo, K. Myakala, M. Herman-Edelstein, L. Qiu, Dong Wang, Yingqiong Peng, A. Grenz, S. Lucia, Evgenia Dobrinskikh, V. D’Agati, H. Koepsell, J. Kopp, A. Rosenberg, M. Levi   +15 more
semanticscholar   +1 more source

Pathogenesis and Treatment of Chronic Kidney Disease: A Review of Our Recent Basic and Clinical Data

Kidney & Blood Pressure Research, 2014
Chronic kidney disease (CKD) is a worldwide public health problem that affects millions of people from all racial and ethnic groups. At end of 2013, over 300,000 Japanese patients had maintenance dialysis therapy (JSDT). In Japan, the major causes of end
Yasuhiko Tomino
doaj   +1 more source

Pharmacological effects of raas blockade in ischemic nephropathy [PDF]

, 2016
Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio, Cianci, Rosario, Coppolino, Giuseppe, Di Mario, Francesca, Farrah, Tariq E., Fuiano, Giorgio, Gigante, Antonietta, Rivoli, Laura, Rosato, Edoardo   +8 more
core   +1 more source

The Heart and Diabetic Nephropathy

Methodist DeBakey Cardiovascular Journal, 2010
BACKGROUND Diabetic nephropathy represents the most common etiology for stage 5 chronic kidney disease in the United States, resulting in the need for dialysis and transplantation. It is estimated that about one-third of U.S. patients who need renal replacement therapy are diabetics.
Juan Jorge Olivero, Peter T. Nguyen, Juan Jose Olivero, Anna Kagan   +3 more
openaire   +4 more sources

Classification and Differential Diagnosis of Diabetic Nephropathy

Journal of Diabetes Research, 2017
Diabetic nephropathy (DN) is a major cause of end-stage renal disease throughout the world in both developed and developing countries. This review briefly introduces the characteristic pathological changes of DN and Tervaert pathological classification ...
Chenyang Qi, Xing Mao, Zhigang Zhang, Huijuan Wu   +3 more
semanticscholar   +1 more source

Rodent models of diabetic nephropathy: their utility and limitations

International Journal of Nephrology and Renovascular Disease, 2016
Munehiro Kitada,1,2 Yoshio Ogura,2 Daisuke Koya1,2 1Division of Anticipatory Molecular Food Science and Technology, Medical Research Institute, 2Department of Diabetology and Endocrinology, Kanazawa Medical University, Uchinada, Ishikawa, Japan Abstract:
Kitada M, Ogura Y, Koya D
doaj