Results 61 to 70 of about 845,031 (279)
Hyperoside ameliorates diabetic nephropathy induced by STZ via targeting the miR-499–5p/APC axis
Journal of Pharmacological Sciences, 2021 Diabetic nephropathy is a serious complication of diabetes. Hyperoside has been widely reported to ameliorate diabetes-associated disease. The current study is designed to explore the mechanism of hyperoside in diabetic nephropathy. In the present study,
Jingbo Zhou +5 more
doaj +1 more source
Tubulointerstitial injury and proximal tubule albumin transport in early diabetic nephropathy induced by type 1 diabetes mellitus [PDF]
, 2017 A decrease in the tubular expression of albumin endocytic transporters megalin and cubilin has been associated with diabetic nephropathy (DN), but there are no comprehensive studies to date relating early tubulointerstitial injury and the effect of the ...
Bahamonde, Javiera +3 more
core
Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]
, 2018 Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J. +2 more
core +1 more source
Vasopressin and diabetic nephropathy [PDF]
Current Opinion in Nephrology and Hypertension, 2017 The prevalence of diabetic kidney disease (DKD) is increasing worldwide. Despite major therapeutic advances in the last decades in DKD, the current standard of care let many people progress to severe stages. Vasopressin secretion is increased in diabetes, and its potential role in the onset and progression of DKD is being re-investigated.Recently ...
Roussel, Ronan +2 more
openaire +3 more sources
PočkiBackground. Diabetic nephropathy is a serious side effect of both type 1 and 2 diabetes mellitus. Toll-like receptor 4 (TLR4), the first identified and most extensively studied member of the TLR family, has been implicated in the development of various ...
Ayat Rasheed Hameed, Rasha Salih Nuhair
doaj +1 more source
Recent Progress in Genetics and Epigenetics Research on Diabetic Nephropathy in Malaysia
Journal of Diabetes Research, 2023 Diabetic nephropathy is a multifactorial disease. Gene susceptibility, as well as environmental exposure, plays an important role in disease progression.
Norhashimah Abu Seman +1 more
doaj +1 more source
Diabetic Nephropathy without Diabetes [PDF]
Journal of Clinical Medicine, 2015 Diabetic nephropathy without diabetes (DNND), previously known as idiopathic nodular glomerulosclerosis, is an uncommon entity and thus rarely suspected; diagnosis is histological once diabetes is discarded. In this study we describe two new cases of DNND and review the literature. We analyzed all the individualized data of previous publications except
Elia Pérez Fernández +5 more
openaire +4 more sources
Scientific Reports, 2019 Extracellular vesicles (EVs) that are derived from mesenchymal stromal cells (MSCs) have been shown to reprogram injured cells by activating regenerative processes.
C. Grange +6 more
semanticscholar +1 more source
Sestrin2 Signaling Pathway Regulates Podocyte Biology and Protects against Diabetic Nephropathy
Journal of Diabetes Research, 2023 Sestrin2 regulates cell homeostasis and is an upstream signaling molecule for several signaling pathways. Sestrin2 leads to AMP-activated protein kinase- (AMPK-) and GTPase-activating protein activity toward Rags (GATOR) 1-mediated inhibition of ...
Moein Ala
doaj +1 more source
The Clinical Value of Serum Adropin Level in Early Detection of Diabetic Nephropathy
Kidney & Blood Pressure Research, 2021 Background/Aims: Adropin is a metabolic hormone secreted by the liver, brain, and many peripheral tissues and is involved in energy homeostasis and insulin sensitivity.
Ali Es-haghi +2 more
doaj +1 more source