Results 71 to 80 of about 845,031 (279)
Progression of diabetic nephropathy [PDF]
Kidney International, 2001 Diabetic nephropathy is a major cause of renal failure. The decline in glomerular filtration rate (GFR) is highly variable, ranging from 2 to 20, with a median of 12 mL/min/year. The risk factors of losing filtration power (progression promoters) have not been clearly identified.
Peter Rossing +4 more
openaire +3 more sources
Oxidative Stress, Apoptosis, and Mitochondrial Function in Diabetic Nephropathy
International Journal of Endocrinology, 2018 Diabetic nephropathy (DN) is the second most frequent and prevalent complication of diabetes mellitus (DM). The increase in the production of oxidative stress (OS) is induced by the persistent hyperglycemic state capable of producing oxidative damage to ...
Sonia Sifuentes-Franco +3 more
semanticscholar +1 more source
Glycopatterns of Urinary Protein as New Potential Diagnosis Indicators for Diabetic Nephropathy
Journal of Diabetes Research, 2017 Diabetic nephropathy is a major cause of chronic kidney disease and end-stage kidney disease. However, so little is known about alterations of the glycopatterns in urine with the development of diabetic nephropathy.
Hanyu Zhu +13 more
doaj +1 more source
The Signaling of Cellular Senescence in Diabetic Nephropathy
Oxidative Medicine and Cellular Longevity, 2019 Diabetic nephropathy is the leading cause of chronic kidney disease (CKD) in western countries. Notably, it has a rapidly rising prevalence in China. The patients, commonly complicated with cardiovascular diseases and neurologic disorders, are at high ...
Yabing Xiong, Lili Zhou
semanticscholar +1 more source
The Egyptian Journal of Internal Medicine, 2021 Background Matrix metalloproteinase 9 (MMP-9) is an important inflammatory marker in diabetic nephropathy. Many studies assessed the association between MMP-9 gene polymorphism and different microvascular complications of type 2 diabetes mellitus, though
Kholoud Shalaby +4 more
doaj +1 more source
Renal Hyperfiltration and the Development of Microalbuminuria in Type 1 Diabetes [PDF]
, 2009 OBJECTIVE: The purpose of this study was to examine prospectively whether renal hyperfiltration is associated with the development of microalbuminuria in patients with type 1 diabetes, after taking into account known risk factors.
Aschengrau, Ann +6 more
core +3 more sources
Experimental and Clinical Endocrinology & Diabetes, 2021 Martina Guthoff +4 more
openaire +3 more sources
Evolving spectrum of diabetic nephropathy
World Journal of Diabetes, 2019 Diabetes remains an important health issue as more patients with chronic and uncontrolled diabetes develop diabetic nephropathy (DN), which classically presents with proteinuria followed by a progressive decrease in renal function. However, an increasing
J. Kopel +2 more
semanticscholar +1 more source
Mediators of Inflammation, 2015 This review emphasizes the role of oxidative stress in diabetic nephropathy, acting as trigger, modulator, and linker within the complex network of pathologic events.
Gina Manda +3 more
doaj +1 more source
Diabetic nephropathy, autophagy and proximal tubule protein endocytic transport: A potentially harmful relationship [PDF]
, 2018 Diabetic nephropathy (DN) is the most frequent cause of chronic renal failure. Until now, the pathophysiological mechanisms that determine its development and progression have not yet been elucidated.
Agüero, Rocio +4 more
core