Results 71 to 80 of about 753,615 (353)
Is Uric Acid elevation a random finding or a causative agent of diabetic nephropathy?
Revista da Associação Médica Brasileira, 2019 OBJECTIVE In this study, we aimed to analyze the relationship between serum uric acid (UA) and microalbuminuria as a marker of renal injury in type 2 diabetes mellitus.
M. Koçak +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.Compared with those on the pTi surface, macrophages on the TNTs surface present reduced myosin II contractility, which facilitates the nuclear translocation of the UTX. This reduction decreases the enrichment of the repressive H3K27me3 histone modification at the Abca1 gene locus, which promotes the transcription and protein expression of ABCA1 ...
Hengji Jia +8 more
wiley +1 more source
Tubulointerstitial Biomarkers for Diabetic Nephropathy
Journal of Diabetes Research, 2018 Patients with diabetic nephropathy have a higher risk of mortality, mostly from cardiovascular complications. Standard biomarkers including serum creatinine, estimated glomerular filtration rate, and albuminuria are imprecise, do not directly measure ...
B. Satirapoj
semanticscholar +1 more source
Angiopoietins and diabetic nephropathy [PDF]
Diabetologia, 2016 Diabetic nephropathy is the main cause of end-stage renal failure in the Western world. In diabetes, metabolic and haemodynamic perturbations disrupt the integrity of the glomerular filtration barrier, leading to ultrastructural alterations of the glomeruli, including podocyte foot process fusion and detachment, glomerular basement membrane thickening,
openaire +6 more sources
Supramolecular Assembly of Triterpenoids: Current State and Biomedical Perspectives
Aggregate, EarlyView.Triterpenoids serve as both exceptional molecular motifs for supramolecular assembly and versatile therapeutic agents, offering broad biological functions to improve health outcomes and enhance treatment efficacy. This review comprehensively summarizes recent advances in triterpenoid‐based supramolecular systems, including their roles as functional ...
Jie Zhong +3 more
wiley +1 more source
The Egyptian Journal of Internal Medicine, 2013 Background Diabetic nephropathy is one of the debilitating complications of type 2 diabetes and the leading cause for end-stage renal disease requiring renal replacement therapy.
Asmaa I. Ahmed +3 more
doaj +1 more source
Pathogenesis of diabetic nephropathy [PDF]
Journal of Diabetes Investigation, 2011 As the increasing prevalence of diabetes reaches epidemic proportions worldwide, diabetic nephropathy and associated end-stage renal failure will be an unavoidable major health burden to not only individuals with diabetes and their families, but also to the health systems both in developed and developing countries. Over the past decade, a large body of
Mark E. Cooper, Zemin Cao
openaire +3 more sources
Animal Models and Experimental Medicine, EarlyView.The experimental type 2 diabetes model in rats induced by streptozotocin and nicotinamide showed that silver nanoparticles synthesized from lemongrass extract modulate blood glucose, water and food intake, and enhance antioxidant enzyme synthesis and weight gains.
Milad Faraji +6 more
wiley +1 more source
Advances in early biomarkers of diabetic nephropathy.
Revista da Associação Médica Brasileira, 2018 Diabetic nephropathy is the main cause of chronic kidney disease, and represents the most common and serious complication of diabetes. The exact pathogenesis is complex and not elucidated.
Jin Zhang, Jianhua Liu, Xiaosong Qin
semanticscholar +1 more source
Animal Models and Experimental Medicine, EarlyView.Neutrophil‐to‐lymphocyte ratio (NLR) and monocyte‐to‐lymphocyte ratio (MLR) were investigated as potential markers. A total of 3545 subjects were included in the analysis retrospectively. Adult men and women with impaired glucose metabolism were assessed. NLR and MLR may help assess inflammation in individuals with impaired glucose metabolism. Abstract
Ayed A. Dera +11 more
wiley +1 more source