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Perspectives on the News commentaries are now part of a new, free monthly CME activity. The Mount Sinai School of Medicine, New York, New York, is designating this activity for 2.0 AMA PRA Category 1 credits. If you wish to participate, review this article and visit www.diabetes.procampus.net to complete a posttest and receive a certificate.
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INTRODUCTION: Diabetic neuropathy is a complication seen in diabetic patients and involves motor, sensory or autonomic nerve fibers due to minor vessel damage.
Mahmut Tanırlar +4 more
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Functional and Structural Changes of the Blood-Nerve-Barrier in Diabetic Neuropathy
The incidence of diabetes mellitus is approaching global epidemic proportions and should be considered a major health-care problem of modern societies in the twenty-first century.
Mette Richner +9 more
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Perspectives of glycemic variability in diabetic neuropathy: a comprehensive review
Zhang et al. describe metrics for evaluating glycaemic variability (GV) in clinical practice and summarize the role and related mechanisms of GV in diabetic neuropathy, including cardiovascular autonomic neuropathy, diabetic peripheral neuropathy and ...
Xiaochun Zhang +3 more
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Peripheral Glial Cells in the Development of Diabetic Neuropathy
The global prevalence of diabetes is rapidly increasing, affecting more than half a billion individuals within the next few years. As diabetes negatively affects several physiological systems, this dramatic increase represents not only impaired quality ...
Nádia Pereira Gonçalves +4 more
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Circular RNAs (circRNAs) play a vital role in diabetic peripheral neuropathy. However, their expression and function in Schwann cells in individuals with diabetic peripheral neuropathy remain poorly understood.
Yu-Tian Liu +12 more
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This article provides an overview for understanding the diagnosis, pathogenesis, and management of diabetic neuropathy.New information about the pathogenesis of diabetic neuropathy continues to emerge, which will lead to identifying new drug targets. It is clear that the natural history of diabetic neuropathy is changing and the rate of progression is ...
James W, Russell, Lindsay A, Zilliox
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Research progress on inflammatory mechanism of diabetic neuropathy [PDF]
Diabetic neuropathy is a common complication of diabetes, but the mechanism remains unclear. Recent studies have shown that inflammation may play a critical role in the development and progression of diabetic neuropathy.
JIANG Ye, YU Zhuoying, LI Min
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Introduction: Peripheral neuropathy is a common microvascular complication in patients with type 2 diabetes mellitus with a prevalence of around 50%. Objectives: This prospective observational cross-sectional study was done to assess serum calprotectin ...
Ramanathan Velayutham +3 more
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Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
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