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Tocotrienols: A Review From Source to Therapeutic Applications
Tocotrienols demonstrate superior antioxidant, neuroprotective, and anti‐inflammatory properties compared to conventional vitamin E forms, with promising therapeutic applications across multiple disorders when delivered through optimized systems that enhance their inherently limited bioavailability.
Natalia‐Carolina Londoño +6 more
wiley +1 more source
Serum vitamin D is substantially reduced and predicts flares in diabetic retinopathy patients
Aims/Introduction Research has suggested that vitamin D deficiency is associated with diabetic retinopathy (DR). Our study aimed to determine whether vitamin D deficiency is the cause of diabetic retinopathy or if diabetic retinopathy reduces vitamin D ...
Yong Zhuang +4 more
doaj +1 more source
Author Correction: Network pharmacology and molecular docking study on the active ingredients of qidengmingmu capsule for the treatment of diabetic retinopathy [PDF]
Mingxu Zhang +4 more
openalex +1 more source
Abstract Introduction Pre‐eclampsia (PE) involves systemic endothelial dysfunction and microvascular injury, yet routine obstetric care lacks noninvasive readouts of maternal microvascular health. We evaluated whether hypertensive retinopathy (HR) detected during pregnancy is associated with maternal disease severity and adverse neonatal outcomes ...
Gabriele Saccone +6 more
wiley +1 more source
Early matrine intervention of gut microbiota for type 2 diabetes prevention
How matrine influences gut microbiota imbalance to prevent the progression of diabetes remains unclear. We conduct experiments using mice to simulate the stages of diabetes development and matrine intervention. Combined with amplicon sequencing, we find that the gut microbiota of diabetic mice continuously changes with the progression of the disease ...
Zhexue Sun +4 more
wiley +1 more source
Gene Therapy for Diabetic Retinopathy in Animal Models and Humans [PDF]
Hiroaki Mizukami
openalex +1 more source
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui +12 more
wiley +1 more source
Our study demonstrates that UV cross‐linking (CXL) reduces outflow facility while increasing corneal elasticity across IOP levels of 20–40 mmHg, measured using direct manometry and non‐contact optical coherence elastography. These results highlight both parameters as potential indicators for evaluating CXL effectiveness and monitoring keratoconus ...
Yilong Zhang +6 more
wiley +1 more source
THEIA™ development, and testing of artificial intelligence‐based primary triage of diabetic retinopathy screening images in New Zealand [PDF]
Ehsan Vaghefi +6 more
openalex +1 more source
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni +6 more
wiley +1 more source

