Results 101 to 110 of about 203,197 (289)

Vascular and Cardiac Target Organ Damage in Type 2 Diabetics With and Without Diabetic Retinopathy

Archives of Clinical and Experimental Surgery, 2013
Objective: In this study, we sought to assess the differences in cardiac and vascular end-organ damage in type 2 diabetics, with and without diabetic retinopathy. Methods: A cross-sectional study of 131 diabetic patients (44 with diabetic retinopathy and
Francisco Leon-Garrigosa, Jessica M Schrieber, J. Javier Servat, Luis Garcia-Ortiz, Jose Ignacio Recio-Rodriguez, Ma Carmen Patino-Alonso, Cristina Agudo-Conde, Emiliano Rodriguez Sanchez, Manuel Angel Gomez-Marcos   +8 more
doaj   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

Food Safety and Health, EarlyView.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar, Sehrish Jabbar, Qudrat Ullah, Farhang Hameed Awlqadr, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Sammra Maqsood, Ali Ikram, Ammar Ahmad Khan, Worawan Panpipat, Manat Chaijan   +10 more
wiley   +1 more source

Management of diabetic retinopathy

Indian Journal of Ophthalmology, 2000
Diabetic retinopathy remains a major cause of blindness despite increased understanding of this disease and identification of successful treatments.
Saxena Sandeep, Jalali Subhadra, Meredith Travis, Holekamp Nancy, Kumar Dipak   +4 more
doaj  

The role of gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

Frontiers in Immunology
Diabetic retinopathy, a prevalent microvascular complication of diabetes mellitus, is characterized by its increasing global prevalence and stands as the leading cause of visual impairment and blindness in adults. The pathogenesis of diabetic retinopathy
Liqing Xie, Wenjian Lin
doaj   +1 more source

Artificial Intelligence in Ophthalmology: Current Status, Challenges, and Future Perspectives

Health Care Science, EarlyView.
Current research of artificial intelligence (AI) in ophthalmology. ABSTRACT Artificial intelligence (AI) is revolutionizing ophthalmology by providing innovative solutions for disease screening, diagnosis, personalized treatment, and the delivery of global healthcare services.
She Chongyang, Tao Yong
wiley   +1 more source

Challenges and Solutions in Deploying Systematized Nomenclature of Medicine—Clinical Terms in the Chinese Healthcare Context

Health Care Science, EarlyView.
ABSTRACT Systematized nomenclature of medicine—clinical terms (SNOMED CT), one of the most comprehensive clinical terminology systems, is pivotal in enhancing healthcare interoperability, clinical data governance, and medical artificial intelligence (AI) development globally.
Ge Wu, Jiale Nan, Yanmei Chen, Chao Liu, Taotao Fu, Xudong Lu, Yani Chen, Zhirong Zeng, You Wu, Mengchun Gong   +9 more
wiley   +1 more source

Berberine alleviates cell pyroptosis in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Pathological Evidence Exploration in Deep Retinal Image Diagnosis

, 2018
Though deep learning has shown successful performance in classifying the label and severity stage of certain disease, most of them give few evidence on how to make prediction.
Cheng, Tingting, Dai, Xunzhang, Gu, Lin, Lu, Feng, Lv, Feifan, Niu, Yuhao, Sato, Imari, Wang, Zongji, Xiao, Yangyan, Zhang, Zijian   +9 more
core   +1 more source

Hypertensive retinopathy in pre‐eclampsia and its association with disease severity and neonatal outcomes: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Introduction Pre‐eclampsia (PE) involves systemic endothelial dysfunction and microvascular injury, yet routine obstetric care lacks noninvasive readouts of maternal microvascular health. We evaluated whether hypertensive retinopathy (HR) detected during pregnancy is associated with maternal disease severity and adverse neonatal outcomes ...
Gabriele Saccone, Francesco Matarazzo, Mariarosaria Motta, Marika Rovetto, Michele Rinaldi, Maurizio Guida, Ciro Costagliola   +6 more
wiley   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source