Results 181 to 190 of about 109,708 (338)

Integrating construction and spatial imaging of organoid for tumor metabolic heterogeneity and interactions

VIEW, EarlyView.
Enzymatically derived tissue debris (TD) is utilized to establish patient‐derived lung cancer tissue spheres (LCOs), which, in conjunction with mass spectrometry imaging, enable the investigation of tumor metabolic heterogeneity and maintenance of CSCs.
Ling Guo, Zhaohua Xia, Jiaxin Wang, Xiaoling Yu, Chuanyue Wu, Qian Luo, Chao Zhao   +6 more
wiley   +1 more source

Metabolic importance of adipose tissue monoacylglycerol acyltransferase 1 in mice and humans [PDF]

, 2018
Finck, Brian N., Franczyk, Michael, H. Liss, Kim H., Hall, Angela M., Klein, Samuel, Lutkewitte, Andrew J., Pietka, Terri, Yoshino, Jun   +7 more
core   +2 more sources

Characterization of 1,2-diacylglycerol hydrolysis in human platelets. Demonstration of an arachidonoyl-monoacylglycerol intermediate.

, 1983
S M Prescott, Philip W. Majerus
openalex   +1 more source

CDP-diacylglycerol synthase activity in Clostridium perfringens [PDF]

, 1982
George Carman, R L Zaniewski, J J Cousminer   +2 more
openalex   +1 more source

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

VIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma, Junxin Chen, Yuan Du, Zhihao Cao, Weizhi Ji, Yuyu Niu, Zebin Yang   +6 more
wiley   +1 more source

Effect of diacylglycerol lipase inhibitor RHC 80267 on pancreatic mouse islet metabolism and insulin secretion [PDF]

, 1989
Kirsten Capito, S. E. Hansen, C. J. Hedeskov, Peter Thams   +3 more
openalex   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

The nature of protein kinase C activation by physically defined phospholipid vesicles and diacylglycerols.

, 1985
Lawrence T. Boni, Robert R. Rando
openalex   +1 more source

REGULATION DIFFERENTIELLE DES PROTO-ONCOGENES JUN PAR LES VOIES DEPENDANTES DU DIACYLGLYCEROL ET DE L'AMPc [PDF]

, 1989
Fatima Mechta‐Grigoriou, Jacques Piette, S Hirai, Moshé Yaniv   +3 more
openalex   +1 more source

Microinjection‐enabled gene silencing in first instar larvae of western flower thrips, Frankliniella occidentalis, reveals vital genes for larval survival

Insect Science, EarlyView.
This study introduces a microinjection technique to deliver dsRNA into the hemolymph of first instar larval thrips (L1s) via the foreleg coxa, enhancing survival rates by minimizing internal tissue damage. Significant knockdown of V‐ATPase‐B, CYP3653A2, and ApoLp‐II/I was achieved, with silencing of CYP3653A2 or ApoLp‐II/I increasing larval mortality ...
Jinlong Han, Dorith Rotenberg
wiley   +1 more source