Results 211 to 220 of about 109,708 (338)

Discovery‐Replication Strategy Identifies Serum Metabolite Biomarkers for Colorectal Cancer in a Chinese Cohort

open access: yesCancer Science, EarlyView.
This study used an untargeted metabolomics approach to screen for serum differentially abundant metabolites in colorectal cancer (CRC) patients, and after analyzing a discovery cohort and validation cohort, eight metabolites and their constituent panels were identified as not only having diagnostic value for CRC but also showing value for the early ...
Lugen Zuo   +10 more
wiley   +1 more source

FAM20C Modulates Neuronal Differentiation in Hypoxic–Ischemic Brain Damage via KAP1 Phosphorylation and LINE1 RNA m6A‐Dependent H3K9me3 Regulation

open access: yesCell Proliferation, EarlyView.
FAM20C regulates the composition of the YTHDC1‐NCL‐KAP1‐LINE1 RNAs complex, thereby affecting neuronal differentiation in hypoxic–ischemic brain damage (HIBD). ABSTRACT Neurodevelopmental impairment due to hypoxic–ischemic brain damage (HIBD) lacks effective biomarkers and therapeutic targets.
Chen‐xi Feng   +8 more
wiley   +1 more source

Effects of Diacylglycerol Oil on Overweight or Obese Patients with Diabetes or Prediabetes: a Single-Arm Trial. [PDF]

open access: yesDiabetes Metab Syndr Obes
Zhong B   +9 more
europepmc   +1 more source

Crystal structure and biophysical characterisation of the enterococcal foldase PpiC, a cross‐opsonic antigen against gram‐positive nosocomial pathogens

open access: yesThe FEBS Journal, EarlyView.
PpiC is an enterococcal lipoprotein endowed with both Peptidyl‐prolyl cis‐trans isomerase (PPIase) and foldase activities. It is a potential target for novel antimicrobials and a promising vaccine antigen. We determined the crystal structure of the enzyme, showing that PpiC adopts a dimeric organisation embedding two catalytic parvulin‐type PPIase ...
Valeria Napolitano   +7 more
wiley   +1 more source

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