Results 291 to 300 of about 109,708 (338)

Polarization of Tumor Cells and Tumor‐Associated Macrophages: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 9, September 2025.
Bidirectional metabolic interactions between tumor cells and TAMs in the TME metabolic reprogramming facilitates reciprocal crosstalk between TAMs and tumor cells within the immunosuppressive TME. This interaction promotes both the pro‐tumor functions of TAMs and tumor mesenchymal transition through complex molecular signaling.
Guohao Wei   +7 more
wiley   +1 more source

Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons

open access: yesSmall Science, Volume 5, Issue 9, September 2025.
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong   +4 more
wiley   +1 more source

Effects of phospholipase C inhibition on the regulation of membrane lipid metabolism in maize leaves. [PDF]

open access: yesFront Plant Sci
Wei Y   +9 more
europepmc   +1 more source

Dissecting the genomic regions, candidate genes and pathways using multi‐locus genome‐wide association study for stem rot disease resistance in groundnut

open access: yesThe Plant Genome, Volume 18, Issue 3, September 2025.
Abstract Stem rot, caused by Sclerotium rolfsii Sacc., is a devastating soil‐borne disease causing up to 80% yield losses in groundnut globally. To dissect the genetic basis of resistance, we evaluated a diverse minicore germplasm panel over 3 years in stem rot sick‐field conditions.
H. V. Veerendrakumar   +11 more
wiley   +1 more source

Insights into the genetic and biochemical basis of Gibberella ear rot resistance in maize

open access: yesThe Plant Genome, Volume 18, Issue 3, September 2025.
Abstract Fusarium graminearum colonizes the maize ear, causing Gibberella ear rot (GER) and producing harmful mycotoxins, including deoxynivalenol (DON) and zearalenone (ZEA). The disease can be managed in part by breeding and planting resistant maize cultivars. Resistance to GER is a quantitative and complex trait.
Sarah Lipps   +5 more
wiley   +1 more source

Association of DGAT1 and POU1F1 Gene Polymorphisms With the Milk Traits in the Cross‐Bred Hamdani Sheep Bred Under Extensive Management

open access: yesVeterinary Medicine and Science, Volume 11, Issue 5, September 2025.
DGAT1 gene AluI polymorphism affects milk composition in cross‐bred Hamdani sheep. ABSTRACT Background Milk production and composition are affected by genetic and environmental factors. Among key genetic regulators, the POU1F1 and DGAT1 genes play significant roles.
Ali Osman Turgut   +2 more
wiley   +1 more source

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