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Identification of circulating metabolites associated with chronic rhinosinusitis using Mendelian randomization analysis. [PDF]

Braz J Otorhinolaryngol
Jiang F, Tu J, Luo W, Jia Y, Luo Q, Ye J.   +5 more
europepmc   +1 more source

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Diacylglycerol kinases

Cellular Signalling, 2004
Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol to form phosphatidic acid. In most cases, members of this large family of enzymes appear to bind and regulate proteins activated by either diacylglycerol or phosphatidic acid. Proteins that appear to be regulated, in part, by DGKs include protein kinase Cs, RasGRPs, and phosphatidylinositol ...
Bai, Luo, Debra S, Regier, Stephen M, Prescott, Matthew K, Topham   +3 more
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Release of diacylglycerol moieties from various glycosyl diacylglycerols

Analytical Biochemistry, 1984
Periodic acid oxidation in methanol followed by incubation with 1, 1-dimethylhydrazine results in release of diacylglycerols from 1,2-diacyl-3-glycosyl-sn-glycerols. During hydrazinolysis of oxidized monogalactosyl diacylglycerol, an intermediate hydrazone derivative was observed which was isolated and identified.
F.J. Heinze, Ernst Heinz, Michael W. Linscheid   +2 more
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Phosphorylation of diacylglycerols

Chemistry of Natural Compounds, 1983
The bulk of the oleic -the 18:1(9) -acid is distributed almost uniformyl between the sn-! and sn-2 positions, and only 24% of its total amount is bound in the sn-3 position. The distribution of the 18:1(6) acid is distinguished by a far higher specificity in relation to the extreme positions.
S. D. Gusakova, T. V. Khomova, Anna I. Glushenkova   +2 more
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Diacylglycerol on lipid metabolism

Current Opinion in Lipidology, 2003
Diacylglycerol is an intermediate product of triacylglycerol hydrolysis and comprises up to 10% of glycerides in plant-derived edible fats and oils. Recent developments in oil chemistry have led to the availability of a novel diacylglycerol oil for clinical studies.
Norio Tada, Hiroshi Yoshida
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Diacylglycerol kinases in cancer

Advances in Biological Regulation, 2017
Diacylglycerol kinases (DGK) are a family of enzymes that catalyze the transformation of diacylglycerol into phosphatidic acid. In T lymphocytes, DGKα and ζ limit the activation of the PLCγ/Ras/ERK axis, providing a critical checkpoint to inhibit T cell responses. Upregulation of these isoforms limits Ras activation, leading to hypo-responsive, anergic
Isabel Mérida, Pedro Torres-Ayuso, Antonia Ávila-Flores, Javier Arranz-Nicolás, Elena Andrada, María Tello-Lafoz, Rosa Liébana, Raquel Arcos   +7 more
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Evolution of the diacylglycerol lipases

Progress in Lipid Research, 2016
Diacylglycerol lipases (DGLs) mainly catalyze "on-demand" biosynthesis of bioactive monoacylglycerols (MAGs) with different long fatty acyl chains, including 2-arachidonoylglycerol (2-AG), 2-linoleoylglycerol (2-LG), 2-oleoylglycerol (2-OG) and 2-palmitoylglycerol (2-PG).
Yonghua Wang, Dongjuan Yuan, Zhongdao Wu
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Effect of phospholipase A2 on rat liver microsomal diacylglycerol cholinephosphotransferase, diacylglycerol ethanolaminephosphotransferase and diacylglycerol acyltransferase

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1978
Abstract Rat liver microsomes were treated with snake venom (Naja naja) phospholipase A2. Effect of the degradation of microsomal major phospholipids were studied on the activities of diacylglycerol cholinephosphotransferase (EC 2.7.8.2), diacylglycerol ethanolaminephosphotransferase (EC 2.7.8.1) and diacylglycerol acyltransferase (EC 2.3.1.20).
Kanoh Hideo, Morimoto Kenji
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