Results 321 to 330 of about 109,708 (338)

Diacylglycerol Kinase

2009
Diacylglycerol kinase (DGK, EC 2.7.1.107) is a lipid kinase that phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). DGK belongs to a well-conserved family of proteins found in diverse species, such as Saccharomyces cerevisiae, Drosophila melanogaster, Caenorhabditis elegans, mammals, plants, and bacteria (Merida et al.
Arisz, S.A., Munnik, T.
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Diacylglycerol Kinases

2003
Publisher Summary Diacylglycerol (DAG) is a prolific second messenger that activates proteins involved in a variety of signaling cascades. Because it can associate with a diverse set of proteins, DAG potentially activates numerous signaling cascades. Thus, its accumulation needs to be strictly regulated.
Steve M. Prescott, Matthew K. Topham
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Diacylglycerol kinase

The International Journal of Biochemistry & Cell Biology, 1997
Recent observations suggest that diacylglycerol kinase (DGK) is one of the key enzymes involved in the regulation of signal transduction. It attenuates protein kinase C activity and cell cycle progression of T-lymphocytes, through controlling the intracellular levels of the second messengers, diacylglycerol and phosphatidic acid.
Hideo Kanoh, Fumio Sakane
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Diacylglycerol, phosphatidic acid, and the converting enzyme, diacylglycerol kinase, in the nucleus

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2006
There exists phosphoinositide (PI) cycle in the nucleus, which is operated differentially from the classical PI cycle at the plasma membrane. Evidence has been accumulated that nuclear PIs and the related enzymes are closely involved in a variety of nuclear processes, although the details remain to be elucidated. In this mini review, some components of
Kaoru Goto, Yasukazu Hozumi, Hisatake Kondo   +2 more
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Studies of diacylglycerol cholinephosphotransferase and diacylglycerol ethanolaminephosphotransferase activities in Tetrahymena microsomes

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1981
Microsomes isolated from Tetrahymena pyriformis synthesized phosphatidylcholine and phosphatidylethanolamine by CDPcholine: 1,2-diacylglycerol cholinephosphotransferase (EC 2.7.8.2) and CDPethanolamine: 1,2-diacylglycerol ethanolaminephosphotransferase (EC 2.7.8.1), utilizing ethanol-dispersed dioleoglycerol.
Yoshinori Nozawa, Yasunaga Kameyama, Isao Hasegawa, Shiro Yoshioka   +3 more
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BIOAVAILABILITY OF DIACYLGLYCEROL MICROEMULSION

Journal of Food Biochemistry, 2011
The bioavailability of diacylglycerol (DAG) microemulsion (DAGM) was investigated in rats. The fatty acid (FA) concentrations in the serum of all rats at 0, 6 and 24h and in feces after oral administration of DAGM and DAG oil were examined. The results showed that the FA concentration of the DAGM group was significantly higher than that of the DAG oil ...
Tianxing Shou, Ying Chen, Duo Li, Qian-Yuan Zhang   +3 more
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Oxidative stability of diacylglycerol oil and butter blends containing diacylglycerols

European Journal of Lipid Science and Technology, 2006
AbstractDiacylglycerol (DAG) oils produced from sunflower oil and traditional sunflower oil were stored for 20 wk at 38 °C, and their oxidative stability was measured. Moreover, two butter blends were produced containing 40 wt‐% DAG oil made from sunflower oil or rapeseed oil, respectively, as well as two control butter blends with sunflower oil or ...
Janni Brogaard Kristensen, Huiling Mu, Charlotte Jacobsen, Nina Skall Nielsen   +3 more
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Inhibition of diacylglycerol kinases as a physiological way to promote diacylglycerol signaling

Advances in Biological Regulation, 2014
Diacylglycerol is a key regulator of cell physiology, controlling the membrane recruitment and activation of signaling molecules. Accordingly, diacylglycerol generation and metabolism are strictly controlled, allowing for localized regulation of its concentration.
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An endogenous regulator of diacylglycerol kinase

Biochemical and Biophysical Research Communications, 1988
During the initial steps of the subcellular fractionation of rat brain homogenate, we recovered more than 100% of diacylglycerol kinase activity. The unusually high yields prompted us to examine the possibility that we had removed an endogenous inhibitor from diacylglycerol kinase during those steps.
Wu Cuizhen, Nancy Klemm, Ingming Jeng
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Properties and functions of diacylglycerol kinases

Cellular Signalling, 2000
Diacylglycerol kinases (DGKs) phosphorylate the second-messenger diacylglycerol (DAG) to phosphatidic acid (PA). The family of DGKs is well conserved among most species. Nine mammalian isotypes have been identified, and are classified into five subgroups based on their primary structure.
Brahim Houssa, Wim J. van Blitterswijk
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