Results 21 to 30 of about 1,286 (153)
The Plant Journal, Volume 106, Issue 5, Page 1247-1259, June 2021., 2021 SUMMARY The unicellular marine diatom Phaeodactylum tricornutum accumulates up to 35% eicosapentaenoic acid (EPA, 20:5n3) and has been used as a model organism to study long chain polyunsaturated fatty acids (LC‐PUFA) biosynthesis due to an excellent annotated genome sequence and established transformation system. In P. tricornutum, the majority of EPA
Richard Smith +6 more
wiley +1 more source
Lipid metabolism in cancer progression and therapeutic strategies
MedComm, Volume 2, Issue 1, Page 27-59, March 2021., 2021 Lipid metabolic reprogramming‐mediated crosstalk between cancer cells and tumor microenvironment contributes to cancer progression. Stromal cells, such as adipocyte, CAF, epithelia cells contribute to lipid metabolic reprogramming in cancer cells. Cancer cells undergo lipid metabolism rewiring to generate building materials for membrane, lipid second ...
Yan Fu +11 more
wiley +1 more source
Regulation of lipid metabolism by the unfolded protein response
Journal of Cellular and Molecular Medicine, Volume 25, Issue 3, Page 1359-1370, February 2021., 2021 Abstract The endoplasmic reticulum (ER) is the site of protein folding and secretion, Ca2+ storage and lipid synthesis in eukaryotic cells. Disruption to protein folding or Ca2+ homeostasis in the ER leads to the accumulation of unfolded proteins, a condition known as ER stress. This leads to activation of the unfolded protein response (UPR) pathway in
Matthieu Moncan +5 more
wiley +1 more source
Plant Direct, Volume 5, Issue 1, January 2021., 2021 Abstract The perennial life style is a successful ecological strategy, and Arabis alpina is a recently developed model Brassicaceae species for studying it. One aspect, poorly investigated until today, concerns the differing patterns of allocation, storage, and metabolism of nutrients between perennials and annuals and the yet unknown signals that ...
Anna Sergeeva +4 more
wiley +1 more source
Mining the bitter melon (momordica charantia l.) seed transcriptome by 454 analysis of non-normalized and normalized cDNA populations for conjugated fatty acid metabolism-related genes [PDF]
, 2010 Background Seeds of Momordica charantia (bitter melon) produce high levels of eleostearic acid, an unusual conjugated fatty acid with industrial value.
Peizhen Yang +4 more
core +1 more source
Phospholipid Membrane Transport and Associated Diseases [PDF]
, 2022 Phospholipids are the basic structure block of eukaryotic membranes, in both the outer and inner membranes, which delimit cell organelles. Phospholipids can also be damaged by oxidative stress produced by mitochondria, for instance, becoming oxidized ...
Hernández-Alvarez, María Isabel +2 more
core +1 more source
Biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites [PDF]
, 2014 Lipid droplets (LDs) are ubiquitous dynamic organelles that store and supply lipids in all eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and production of essential lipid-derived molecules.
Gross, Steven P. +2 more
core +1 more source
A Nutrient Combination that Can Affect Synapse Formation [PDF]
, 2014 Brain neurons form synapses throughout the life span. This process is initiated by neuronal depolarization, however the numbers of synapses thus formed depend on brain levels of three key nutrients—uridine, the omega-3 fatty acid DHA, and choline.
Wurtman, Richard Jay
core +2 more sources
A Brief History of Canola Genetic Gains: From Classical Breeding to Genome Editing. [PDF]
Physiol PlantABSTRACT Canola exemplifies the transformation of a crop from industrial use to a globally significant edible oilseed through sustained genetic and biotechnological innovation. Historically, rapeseed was characterized by high erucic acid and glucosinolate contents, restricting its use primarily to industrial applications.
Azhar M, Cahill DM, Khan GA.
europepmc +2 more sources
Using lipidomics to reveal details of lipid accumulation in developing seeds from oilseed rape (Brassica napus L.) [PDF]
, 2018 With dwindling available agricultural land, concurrent with increased demand for oil, there is much current interest in raising oil crop productivity.
Cazenave-Gassiot, Amaury +5 more
core +3 more sources