Results 31 to 40 of about 1,286 (153)

Daily rhythms of glycerophospholipid synthesis in fibroblast cultures involve differential enzyme contributions [PDF]

, 2013
Circadian clocks regulate the temporal organization of several biochemical processes including lipid metabolism and their disruption leads to severe metabolic disorders. Immortalized cell lines acting as circadian clocks display daily variations in [32P]-
Acosta Rodríguez, Victoria América, Garbarino Pico, Eduardo, Giusto, Norma Maria, Gorne, Lucas Damián, Guido, Mario Eduardo, Marquez, Sebastian, Pasquaré, Susana Juana, Salvador, Gabriela Alejandra   +7 more
core   +2 more sources

Born of frustration: the emergence of Camelina sativa as a platform for lipid biotechnology. [PDF]

Plant Physiol
The emerging crop Camelina sativa (L.) Crantz (camelina) is a Brassicaceae oilseed with a rapidly growing reputation for the deployment of advanced lipid biotechnology and metabolic engineering.
Haslam RP, Michaelson LV, Eastmond PJ, Napier JA.   +3 more
europepmc   +3 more sources

CTP: phosphoethanolamine cytidylytransferase and DAG: CDP-ethanolamine ethanolaminephosphotransferase in the CDP-ethanolamine pathway of Chlamydomonas reinhardtti [PDF]

, 2004
Chlamydomonas reinhardtii Dangeard does not have two major phospholipids, PS and PC. This fact renders C. reinhardtii a desirable system for investigations of the PE biosynthetic pathway and its regulation independent of PC and PS biosynthesis.
Yang, Wenyu
core   +2 more sources

Lipid phosphate phosphatase 3 participates in transport carrier formation and protein trafficking in the early secretory pathway [PDF]

, 2013
The inhibition of phosphatidic acid phosphatase (PAP) activity by propanolol indicates that diacylglycerol (DAG) is required for the formation of transport carriers at the Golgi and for retrograde trafficking to the ER.
Alderton, Ambroggio, Antony, Asp, Bard, Baron, Bechler, Beck, Ben-Tekaya, Ben-Tekaya, Billah, Brindley, Brindley, Brown, Burger, Cabrera, Carrasco, de Figueiredo, Dejgaard, Escalante-Alcalde, Fernández-Ulibarri, Grigoriev, Grigoriev, Grimsey, Hammond, Henneberry, Ho, Huijbregts, Humtsoe, Jackson, Jasinska, Johannes, Kai, Kai, Kano, Kearns, Klumperman, Kooijman, Krauss, Lev, Lippincott-Schwartz, Litvak, Long, Long, Martinez, Martínez-Alonso, Meier, Morikawa, Morris, Mérida, Nagaya, Nilsson, Pappu, Pyne, Pyne, Roberts, Rohde, Roth, Roux, San Pietro, Saraste, Sarri, Schindler, Schmidt, Sciorra, Shemesh, Sigal, Sorre, Subathra, Tian, Ulrix, van Meer, Villani, Waggoner, White, Yang, Yang, Zhang   +77 more
core   +2 more sources

Modifying the lipid content and composition of plant seeds: engineering the production of LC-PUFA [PDF]

, 2014
Omega-3 fatty acids are characterized by a double bond at the third carbon atom from the end of the carbon chain. Latterly, long chain polyunsaturated omega-3 fatty acids such as eicosapentaenoic acid (EPA; 20:5Δ5,8,11,14,17) and docosahexanoic acid (DHA;
Johnathan A. Napier, Noemi Ruiz-Lopez, Olga V. Sayanova, Richard P. Haslam, Sarah Usher   +4 more
core   +2 more sources

Autophagosome formation is initiated at phosphatidylinositol synthase‐enriched ER subdomains [PDF]

, 2017
The autophagosome, a double‐membrane structure mediating degradation of cytoplasmic materials by macroautophagy, is formed in close proximity to the endoplasmic reticulum (ER). However, how the ER membrane is involved in autophagy initiation and to which
Arai, H, Kono, N, Mizushima, N, Nishimura, T, Shimanaka, Y, Tamura, N, Yamamoto, H   +6 more
core   +1 more source

Membrane lipid biosynthesis in Chlamydomonas reinhardtii: Ethanolaminephosphotransferase is capable of synthesizing both phosphatidylcholine and phosphatidylethanolamine [PDF]

, 2004
Phosphatidylethanolamine, but not phosphatidylcholine, is found in Chlamydomonas reinhardtii. A cDNA coding for diacylglycerol: CDP-ethanolamine ethanolaminephosphotransferase (EPT) was cloned from C. reinhardtii. The C.
Moore, Thomas S., Moroney, James V., Yang, Wenyu   +2 more
core   +2 more sources

Triacylglycerol synthesis by PDAT1 in the absence of DGAT1 activity is dependent on re-acylation of LPC by LPCAT2 [PDF]

, 2012
Background: The Arabidopsis thaliana dgat1 mutant, AS11, has an oil content which is decreased by 30%, and a strongly increased ratio of 18:3/20:1, compared to wild type.
Jingyu Xu, Anders S Carlsson, Tammy Francis, Meng Zhang, Travis Hoffman, Michael E Giblin, David C Taylor   +6 more
core   +1 more source

The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth. [PDF]

, 2016
The glycerophospholipid phosphatidylcholine is the most abundant phospholipid species of eukaryotic membranes and essential for structural integrity and signaling function of cell membranes required for cancer cell growth.
Aboagye, EO, Adejumo, T, Brickute, D, Carling, D, Carroll, L, Favicchio, R, Fortt, R, Gottlieb, E, Kaliszczak, M, Kalusa, A, Navaratnam, N, Nguyen, Q, Schug, Z, Tomasi, G, Trousil, S, Twyman, FJ   +15 more
core   +3 more sources

In vivo functional neurochemistry of human cortical cholinergic function during visuospatial attention [PDF]

, 2017
Cortical acetylcholine is involved in key cognitive processes such as visuospatial attention. Dysfunction in the cholinergic system has been described in a number of neuropsychiatric disorders.
A Bidulescu, A Gussew, A Naressi, AJ Ross, Anastasia Christakou, Andrea Motta, AS Berry, B Wauschkuhn, BL Miller, C Gasparovic, CC Hilgetag, CL Colby, CL Nelson, D Apšvalka, D Graveron-Demilly, D Osipova, D Osipova, DJ Holt, E Perry, EA Ennis, G Klatskin, H Zhu, HN Allwörden, J Gates, J-B Poullet, JL Harris, L Kus, L Minati, M a Silver, M Bauer, M Corbetta, M Pinthong, M Sarter, M St. Peters, MD Saltarelli, ME Hasselmo, ME Hasselmo, ME Henry, Michael Lindner, MJ Kuhar, MM Mesulam, N Lally, N Nishitani, Paul Gerald Mullins, PG Mullins, PG Mullins, PR Lockman, R Katz-Brull, R Taylor, S a G Black, S Mangia, S Posse, S Yantis, Somya Iqbal, T Okuda, Tiffany Bell, V Parikh, X-C Wang, Y Boulanger, Y Lin, Z Huang, Z Li   +61 more
core   +7 more sources