Results 41 to 50 of about 1,286 (153)

Triacylglycerol synthesis in rat adipose tissue : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 1983
Adipose tissue consists of two types of cell; the adipocyte and the non-adipocyte {Rodbell, 1964). The adipocyte is unique amongst mammalian cell types in that one class of component {TG) comprises up to 80% of its weight.
Wilson, Russell Douglas
core  

A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury [PDF]

, 2016
In preclinical stages of drug development, anticipating potential adverse drug effects such as toxicity is an important issue for both saving resources and preventing public health risks.
A Carretero, A Lahoz, AE Feldstein, BA Neuschwander-Tetri, CA Smith, D Germano, DJ Hand, DS Wishart, E Fahy, EL LeCluyse, EP Kennedy, F Gibellini, G Ostapowicz, G Quintás, H Horai, H Sawada, J Xia, JC Garcia-Canaveras, JC Garcia-Cañaveras, JC García-Cañaveras, JD Browning, JJ Xu, JJ Xu, JK Nicholson, JM Alakoskela, K Begriche, L Tolosa, L Yuan, LW Sumner, M Benet, M Chagoyen, M Cortes, M Yamazaki, M-P Mingeot-Leclercq, MJ Gomez-Lechon, MJ Gomez-Lechon, MJ Gomez-Lechon, MJ Reasor, ML Greer, MP Holt, MT Donato, MT Donato, MT Donato, MV Brown, N Kaplowitz, PJ O’Brien, PJ O’Brien, S Bijlsma, S Park, SA Shahane, T Hartung, T Pluskal, T Soga, TM Ebbels, UP Kodavanti, VC Abraham, W Yuan, WF Van den Hof, WM Lee, Z Leon   +59 more
core   +1 more source

Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid phosphatase/phosphotransferase enzymes [PDF]

, 2018
Fat storage-inducing transmembrane (FIT or FITM) proteins have been implicated in the partitioning of triacylglycerol to lipid droplets and the budding of lipid droplets from the ER.
Carman, GM, Choudhary, V, Han, G-S, Hayes, M, Levine, T, Loewen, CJ, Ojha, N, Prinz, WA, Shin, JJ   +8 more
core   +1 more source

In silico characterization of 1,2-diacylglycerol cholinephosphotransferase and lysophospha­tidylcholine acyltransferase genes in Glycine max L. Merrill

Genetics and Molecular Research, 2016
The enzymes 1,2-diacylglycerol cholinephosphotrans-ferase (CPT) and lysophosphatidylcholine acyltransferase (LPCAT) are important in lipid metabolism in soybean seeds. Thus, understand-ing the genes that encode these enzymes may enable their modification and aid the improvement of soybean oil quality.
C S, Sousa, B A, Barros, D, Barh, P, Ghosh, V, Azevedo, E G, Barros, M A, Moreira   +6 more
openaire   +2 more sources

Camelina circRNA landscape: Implications for gene regulation and fatty acid metabolism

The Plant Genome, Volume 18, Issue 1, March 2025.
Abstract Circular RNAs (circRNAs) are closed‐loop RNAs forming a covalent bond between their 3′ and 5′ ends, the back splice junction (BSJ), rendering them resistant to exonucleases and thus more stable compared to linear RNAs. Identification of circRNAs and distinction from their cognate linear RNA is only possible by sequencing the BSJ that is unique
Delecia Utley, Brianne Edwards, Asa Budnick, Erich Grotewold, Heike Sederoff   +4 more
wiley   +1 more source

Exploring the connections between ER‐based lipid metabolism and plasma membrane nanodomain signaling

New Phytologist, Volume 243, Issue 1, Page 48-57, July 2024.
Summary Recent advancements in our understanding of cell membrane dynamics have shed light on the importance of plasma membrane (PM) nanodomains in plant cell signaling. Nevertheless, many aspects of membrane nanodomains, including their regulatory mechanisms and biological functions, remain enigmatic.
Xue Pan, Sophia Mastrella, Mohinur Khamzaaliyeva, Didier‐Deschamps Ashley   +3 more
wiley   +1 more source

Mitogenic effects of phosphatidylcholine nanoparticles on MCF-7 breast cancer cells [PDF]

, 2014
Lecithins, mainly composed of the phospholipids phosphatidylcholines (PC), have many different uses in the pharmaceutical and clinical field. PC are involved in structural and biological functions as membrane trafficking processes and cellular signaling.
Corradi, Gerardo Raul, Gándola, Yamila Belén, Irene, Pablo Ezequiel, Miquet, Johanna Gabriela, Pérez, Sebastián E., Sotelo, Ana Isabel   +5 more
core   +1 more source

Arabidopsis diacylglycerol acyltransferase1 mutants require fatty acid desaturation for normal seed development

The Plant Journal, Volume 119, Issue 2, Page 916-926, July 2024.
SUMMARY Diacylglycerol acyltransferase1 (DGAT1) is the major enzyme that synthesizes triacylglycerols (TAG) during Arabidopsis seed development. Mutant dgat1 seeds possess low oil content in addition to a high polyunsaturated fatty acid (PUFA) composition.
Nicholas Neumann, Maxwell Harman, Andrea Kuhlman, Timothy P. Durrett   +3 more
wiley   +1 more source

Targeted mutagenesis of flavonoid biosynthesis pathway genes reveals functional divergence in seed coat colour, oil content and fatty acid composition in Brassica napus L.

Plant Biotechnology Journal, Volume 22, Issue 2, Page 445-459, February 2024.
Summary Yellow‐seed is widely accepted as a good‐quality trait in Brassica crops. Previous studies have shown that the flavonoid biosynthesis pathway is essential for the development of seed colour, but its function in Brassica napus, an important oil crop, is poorly understood. To systematically explore the gene functions of the flavonoid biosynthesis
Huailin Li, Kaidi Yu, Zilu Zhang, Yalun Yu, Jiakai Wan, Hanzi He, Chuchuan Fan   +6 more
wiley   +1 more source

Synthetic redesign of plant lipid metabolism [PDF]

, 2016
Plant seed lipid metabolism is an area of intensive research, including many examples of transgenic events in which oil composition has been modified.
Cahoon, E. B., Haslam, R. P., Kim, H. J., Napier, J. A., Sayanova, O. V.   +4 more
core   +1 more source