Results 121 to 130 of about 45,123 (293)

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli   +3 more
wiley   +1 more source

Novel lipid derivatives for health benefits [PDF]

open access: yes, 2013
Obesity is a public health concern and requires effective management with multiple approaches. Dietary supplements of bioactive compounds that can improve fatty acid oxidation and thermogenesis are currently in focus to develop anti-obese food ...
Madawala, Samanthi R. P.
core  

Negative regulation of diacylglycerol kinase mediates adenosine-dependent hepatocyte preconditioning

open access: yes, 2010
In liver ischemic preconditioning (IP), stimulation of adenosine A2a receptors (A2aR) prevents ischemia/reperfusion injury by promoting diacylglycerol-mediated activation of protein kinase C (PKC).
Carini R.   +12 more
core   +1 more source

A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response [PDF]

open access: hybrid, 2016
Ke Liu   +13 more
openalex   +1 more source

Distinctive gene expression in the reduced first thoracic legs of a nymphalid butterfly

open access: yesInsect Molecular Biology, EarlyView.
Transcriptome analysis reveals that the small non‐walking front legs of a butterfly have distinct gene expression to the four walking legs. Reduced front legs express a gene with putative mechanosensory roles, a blue‐sensitive opsin and two homeobox genes.
Asia E. Hoile   +2 more
wiley   +1 more source

Calcium and cAMP are second messengers in the adipokinetic hormone-induced lipolysis of triacylglycerols in Manduca sexta fat body

open access: yesJournal of Lipid Research, 1999
We have previously shown that stereospecific hydrolysis of stored triacylglycerol by a phosphorylatable triacylglycerol-lipase is the pathway for the adipokinetic hormone-stimulated synthesis of sn-1, 2-diacylglycerol in insect fat body.
Estela L. Arrese   +3 more
doaj   +1 more source

Decoding MAPK cascades in plant immunity: Activation, regulation, integration, and pathogen manipulation

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review focuses on mitogen‐activated protein kinase (MAPK) activation and summarizes how plants regulate and integrate MAPK signaling in modulating plant immune responses. It also examines the effectors pathogens have evolved to manipulate MAPK activation and thereby inhibit plant immunity.
Guitao Zhong   +3 more
wiley   +1 more source

Substrate Chirality and Specificity of Diacylglycerol Kinases and the Multisubstrate Lipid Kinase

open access: yesBiochemistry, 2007
The alpha, zeta, and epsilon isoforms of diacylglycerol kinase exhibit a high degree of stereospecificity in the phosphorylation of diacylglycerol. In comparison, a multiple lipid kinase, MuLK, shows much less stereospecificity, phosphorylating 1,2-dioleoylglycerol only approximately 2-3 times more rapidly than 2,3-dioleoylglycerol.
Epand, Richard M.   +11 more
openaire   +2 more sources

Diacylglycerol Kinase alpha is Involved in the Vitamin E-Induced Amelioration of Diabetic Nephropathy in Mice

open access: yesScientific Reports, 2017
Diabetic nephropathy (DN) is one of vascular complications of diabetes and is caused by abnormal protein kinase C activation as a result of increased diacylglycerol (DG) production in diabetic hyperglycaemia.
Daiki Hayashi   +9 more
doaj   +1 more source

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