Results 171 to 180 of about 539,017 (238)

Diacylglycerol kinase epsilon protects against renal ischemia/reperfusion injury in mice through Krüppel-like factor 15/klotho pathway. [PDF]

open access: yesRen Fail, 2022
Wang Z   +12 more
europepmc   +1 more source

Oxadiazolone‐Triazole Derivatives as a New Scaffold for Modulation of Angiotensin II‐Induced Vascular Contraction

open access: yesChemMedChem, Volume 21, Issue 17, 14 September 2026.
A novel series of candidate AT1 receptor antagonists based on oxadiazolone‐triazole scaffolds was designed and synthesized. Most compounds reduced angiotensin II‐induced vascular contraction in an initial biological screening, with compound 7f emerging as the most active derivative.
Larissa F. L. Ferreira   +5 more
wiley   +1 more source

Spotlight on the Nucleotide: Solid‐State NMR for the Investigation of ATP Hydrolysis in the ATPase SmsC

open access: yesChemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Nucleotide‐detected solid‐state NMR has been applied to probe nucleotide conformations and dynamics during ATP hydrolysis using the dimeric P‐loop ATPase SmsC as a model protein. The different stages of ATP hydrolysis have been mimicked by ATP analogues for which different degrees of conformational heterogeneity have been observed. ABSTRACT Solid‐state
Nina Wehr   +7 more
wiley   +1 more source

AAV-delivered diacylglycerol kinase DGKk achieves long-term rescue of fragile X syndrome mouse model. [PDF]

open access: yesEMBO Mol Med, 2022
Habbas K   +10 more
europepmc   +1 more source

Diacylglycerol Kinase Inhibition Reduces Airway Contraction by Negative Feedback Regulation of Gq-Signaling. [PDF]

open access: yesAm J Respir Cell Mol Biol, 2021
Sharma P   +10 more
europepmc   +1 more source

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