Results 151 to 160 of about 45,123 (293)

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Characterization of proteorhodopsin 2D crystals by electron microscopy and solid state nuclear magnetic resonance

, 2008
Proteorhodopsin (PR) originally isolated from uncultivated γ-Proteobacterium as a result of biodiversity screens, is highly abundant ocean wide.
Shastri, Sarika
core  

Protein kinase C inhibits binding of diacylglycerol kinase-ζ to the retinoblastoma protein

, 2007
We previously showed that the retinoblastoma protein (pRB), a key regulator of G1 to S-phase transition of the cell cycle, binds to and stimulates diacylglycerol kinase-ζ (DGKζ) to phosphorylate the lipid second messenger diacylglycerol into phosphatidic
Divecha, Nullin, Divecha, N., de Widt, J., de Widt, John, Topham, Matthew K., Topham, M. K., van Blitterswijk, W. J., Los, A. P., van Blitterswijk, Wim J., Los, Alrik P.   +9 more
core   +1 more source

Arabidopsis AtDGK7, the Smallest Member of Plant Diacylglycerol Kinases (DGKs), Displays Unique Biochemical Features and Saturates at Low Substrate Concentration [PDF]

, 2005
Fernando Carlos Gómez‐Merino, Fernando Arana-Ceballos, Libia Iris Trejo‐Téllez, Aleksandra Skirycz, Charles A. Brearley, Peter Dörmann, Bernd Mueller‐Roeber   +6 more
openalex   +1 more source

Soybean Inositol Polyphosphate 5‐Phosphatase 8 Confers Salt Tolerance by Reducing Sodium Influx Through Inositol 1,4,5‐Trisphosphate Signalling

Plant, Cell &Environment, Volume 49, Issue 7, Page 4420-4434, July 2026.
ABSTRACT Evidence suggests that the metabolism of inositol and its derivatives may be involved in various biological processes including salt tolerance, but there has been limited understanding. Ectopic expression of Gs5PTase8, an inositol polyphosphate 5‐phosphatase cloned from wild soybean (Glycine soja), significantly enhanced salt tolerance in ...
Qi Jia, Yuan Chen, Defeng Kong, Hanyu Fan, Song Sun, Yuhang Liu, Jiahui Fu, Man‐Wah Li, Fuk‐Ling Wong, Qinghua Li, Kangjing Liang, Hon‐Ming Lam, Wen‐Xiong Lin   +12 more
wiley   +1 more source

Egr2 to the rescue: nanoparticles revitalize natural killer cells in the fight against cancer

The EMBO Journal
Reversal of tumor-induced natural killer (NK) cell dysfunction remains a major hurdle to overcome for the clinical success of immunotherapies based on NK cells targeting solid tumors.
Aline Pfefferle, Santosh Phuyal, Herman Netskar, Karl-Johan Malmberg   +3 more
doaj   +1 more source

Diacylglycerol generated by exogenous phospholipase C activates the mitogen-activated protein kinase pathway independent of Ras- and phorbol ester-sensitive protein kinase C: dependence on protein kinase C-ζ [PDF]

, 1997
M.C.M. van Dijk, Francisco J.G. Muriana, P.C.J. van der Hoeven, John de Widt, Dick Schaap, Wouter H. Moolenaar, Wim J. van Blitterswijk   +6 more
openalex   +1 more source

A Case Series of Sudden Death in Children Aged 12 Months to 4 Years From LPIN1 Deficiency and PPA2 Deficiency in Queensland

Journal of Paediatrics and Child Health, EarlyView.
Sophie Manoy, Sally Smith, Marita Smith, Catherine Atthow, Janette Spicer, Matthew Lynch, Michelle Lipke, Julie A. McEniery, David Coman, Anita Inwood, Jim McGill, Carolyn Bursle   +11 more
wiley   +1 more source

Cannabigerol Alleviates Obesity‐Induced Mitochondrial Dysfunction by Cardiolipin Fatty Acid Remodeling

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Graphical overview of the effects of the high‐fat, high‐sucrose (HFHS) diet regime and 2‐week cannabigerol (CBG) treatment on the intramuscular long‐chain fatty acids (LCFAs) trafficking and lipid metabolism, with subsequent implications for mitochondrial cardiolipin (CL) composition in the red gastrocnemius muscle.
Patrycja Bielawiec, Karolina Konstantynowicz‐Nowicka, Adrian Chabowski, Ewa Harasim‐Symbor   +3 more
wiley   +1 more source

Glucose-induced synthesis of diacylglycerol de novo is associated with translocation (activation) of protein kinase C in rat adipocytes

, 1989
Addition of glucose (5–20 mM) to rat adipocytes provoked dose-related increases in diacylglycerol, without increasing production of [3H]inositol phosphates.
Watson, James E., Farese, Robert V., Joanne Hoffman, James E. Watson, Denise R. Cooper, Robert V. Farese, Hoffman, Joanne, Ishizuka, Tatsuo, Pushkin, David B., Cooper, Denise R., David B. Pushkin, Tatsuo Ishizuka   +11 more
core   +1 more source