Results 201 to 210 of about 916,035 (361)
Activation of Extracellular-signal Regulated Kinase (ERK1/2) by Fluid Shear is Ca\u3csup\u3e2+\u3c/sup\u3e- and ATP-dependent in MC3T3-E1 Osteoblasts [PDF]
To determine the role of Ca2+ signaling in activation of the Mitogen-Activated Protein Kinase (MAPK) pathway, we subjected MC3T3-E1 pre-osteoblastic cells to inhibitors of Ca2+ signaling during application of fluid shear stress (FSS).
Duncan, Randall L.+7 more
core +1 more source
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya+3 more
wiley +1 more source
Signaling at the membrane interface by the DGK/SK enzyme family
The sphingosine (SK) and diacylglycerol (DGK) kinases have become the subject of considerable focus recently due to their involvement as signaling enzymes in a variety of important biological processes.
Daniel M. Raben, Binks W. Wattenberg
doaj
Alternative splicing of the human diacylglycerol kinase ζ gene in muscle [PDF]
Li Ding+5 more
openalex +1 more source
Myristic acid selectively augments β-tubulin levels in C2C12 myotubes via diacylglycerol kinase δ. [PDF]
Sakai H+3 more
europepmc +1 more source
This study demonstrates the antiobesity potential of Halymenia durvillei (H. durvillei) extracts using a Caenorhabditis elegans (C. elegans) obesity model. The extracts significantly reduced total fat accumulation, lowered reactive oxygen species (ROS) levels, and extended the lifespan in glucose‐fed C. elegans. These beneficial effects may be mediated
Kawita Chumphoochai+8 more
wiley +1 more source
Evidence for Involvement of Protein Kinase C (PKC)- and Noninvolvement of Diacylglycerol-Sensitive PKCs in Insulin-Stimulated Glucose Transport in L6 Myotubes [PDF]
Gautam Bandyopadhyay
openalex +1 more source
Diacylglycerol Kinase Puts the Brakes on Airway Smooth Muscle Contraction. [PDF]
Lukovic E, Emala C.
europepmc +1 more source
ABSTRACT Background Anticancer chemotherapy is an underappreciated contributor to cancer cachexia, an often‐irreversible body‐wasting condition that causes 20%–30% of cancer‐related deaths. An obstacle to predicting, monitoring and understanding the mechanisms underlying chemotherapy cachexia is that each cancer (and subtype) is assigned different ...
Dean G. Campelj+9 more
wiley +1 more source