Results 151 to 160 of about 373,653 (317)

Serum 27-nor-5 beta-Cholestane-3,7,12,24,25 Pentol Glucuronide Discovered by Metabolomics as Potential Diagnostic Biomarker for Epithelium Ovarian Cancer

, 2011
Serum 27-nor-5 beta-Cholestane-3,7,12,24,25 Pentol Glucuronide Discovered by Metabolomics as Potential Diagnostic Biomarker for Epithelium Ovarian CancerThe aim of this study was to use a two steps strategy metabolomics to screen/identify and validate ...
Wang, Y.S., Jing Chen, 许国旺, Zhiliang Xu, Schmitt-Kopplin, Philippe, Zhang, X.Y., Lu, X., Xin Lu, Guowang Xu, Rui Cao, Sumin Zhao, Zhao, N.Q., Xiaoyan Zhang, Wang, Yisheng, Congjian Xu, XuCongjian, Xiaoping Wan, Xu, Zhiliang, Xu, G.W., Xu, C.J., Xu, Congjian, Qiang Huang, Zhao, Naiqing, Wan, Xiaoping, Zhang, Xiaoyan, Xu, Guowang, Naiqing Zhao, Xiaohua Wu, Zhao, Sumin, Huang, Q., Agnes Fekete, Yisheng Wang, Huang, Qiang, Xu, Z.L., Wu, Xiaohua, Wan, X.P., Wu, X.H., Zhao, S.M., Cao, Rui, Chen, J., Fekete, A., Cao, R., Philippe Schmitt-Kopplin, Lu, Xin, Fekete, Agnes, Chen, Jing, Schmitt-Kopplin, P.   +46 more
core   +1 more source

Glyphosate-Induced Metabolic and Immune Modulation in Hepatoma Cells: Identification of Key Genes as Diagnostic and Therapeutic Targets Using an In Silico Systems Biology Approach

Journal of Xenobiotics
Glyphosate, one of the most widely used herbicides worldwide, has raised significant concerns regarding its potential involvement in hepatotoxicity and molecular changes associated with liver cancer biology.
Divya Mishra
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Gut microbial and functional signatures in breast cancer: an integrated metagenomic and machine learning approach to non-invasive detection

Frontiers in Microbiology
IntroductionBreast cancer is associated with significant restructuring of the gut ecosystem. Gut microbial composition and function may influence cancer development and progression through immune modulation, metabolic regulation, and inflammation-related
Yalin Li, Yalin Li, Yalin Li, Yi Cheng, Yi Cheng, Yi Cheng, Weichi Liu, Weichi Liu, Weichi Liu, Jingjin Li, Jingjin Li, Jingjin Li, Shiqi Li, Suriguga, Teng Ma, Teng Ma, Teng Ma, Lai-Yu Kwok, Lai-Yu Kwok, Lai-Yu Kwok, Zhihui Cai, Zhihong Sun, Zhihong Sun, Zhihong Sun   +23 more
doaj   +1 more source

Procalcitonin as diagnostic biomarker of sepsis

The Lancet Infectious Diseases, 2013
Afshari, Arash, Harbarth, Stéphan Juergen   +1 more
openaire   +5 more sources

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Inflammatory cytokines and combined biomarker panels in pancreatic ductal adenocarcinoma: Enhancing diagnostic accuracy

, 2019
BackgroundEarly diagnosis of pancreatic ductal adenocarcinoma (PDAC) is challenged by the absence of accurate early diagnostic and prognostic biomarkers. CA19-9 is the established, diagnostic tumour marker in PDAC, despite its limitations.
Nicola Lahoud (7251413), Yandiswa Y Yako, John Devar, John Devar (7251410), Martin Smith, Martin Smith (51258), Nicola Lahoud, Kruger, Deirdre, Yako, Yandiswa Y, Lahoud, Nicola, Yandiswa Y. Yako (7251407), Devar, John, Deirdré Kruger, Smith, Martin, Deirdré Kruger (3171861)   +14 more
core   +1 more source

The diagnostic and immunomodulatory role of IL-37 in pediatric sepsis

Frontiers in Immunology
ObjectiveSepsis arises from a dysregulated host inflammatory response to infection. The levels and pathogenic role of interleukin-37 (IL-37) in pediatric sepsis remain to be fully elucidated.MethodsSerum IL-37 concentrations were measured in two ...
Jin Ma, Yanling Zhang, Changrui Sun, Hao Yang, Zhixin Song, Feiqi Huang, Chunxiang Wu   +6 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source