Results 111 to 120 of about 853,706 (301)

Analysing false‐positive errors when Australian radiographers use preliminary image evaluation

Journal of Medical Radiation Sciences
Introduction Diagnostic errors in the emergency departments can have major implications on patient outcomes. Preliminary Image Evaluation (PIE) is a brief comment written by a radiographer describing an acute or traumatic pathology on a radiograph and ...
Jermayne Takapautolo, Michael Neep, Deborah Starkey   +2 more
doaj   +1 more source

The impact of systematic uncertainties in stellar parameters on integrated spectra of stellar populations

, 2009
In this paper we investigate a hitherto unexplored source of potentially significant error in stellar population synthesis (SPS) models, caused by systematic uncertainties associated with the three fundamental stellar atmospheric parameters; effective ...
Alonso, Bruzual, Cenarro, Maurizio Salaris, Percival, Pietrinferni, Ramírez, Schiavon, Schiavon, Schiavon, Schiavon, Susan M. Percival, Trager, Trager, Vazdekis, Vázquez, Worthey   +16 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Diagnosing aortic dissection: A review of this elusive, lethal diagnosis

Journal of the American College of Emergency Physicians Open
Aortic dissection (AD) remains a difficult diagnosis in the emergency setting. Despite its rare occurrence, it is a life‐threatening pathology that, if missed, is typically fatal.
Blake Briggs, David Cline
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Endodontic Consequences of Early Stage of Medication‐Related Osteonecrosis of the Jaw: A Case Report

Clinical and Experimental Dental Research
Objectives Osteonecrosis of the jaws (MRONJ) is a frequent side effect of antiresorptive (AR) drugs used in oncology. MRONJ may have endodontic consequences, as reported in this clinical case.
Vanessa Baaroun, Samantha Elbhar, Carole Rémond, Ines Guessoum, Juliette Rochefort, Geraldine Lescaille, Yves Boucher, Marjorie Zanini   +7 more
doaj   +1 more source

Diagnostic error reduction in the United States and Italy through the intervention of diagnostic management teams [PDF]

, 2018
A major challenge to most countries is the growing cost of healthcare. The cost of laboratory testing is approximately 3% of the total clinical costs.
Adriana Berumen Velazquez, Michael Laposata, Roberto Verna   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Repeated Visits to a Woman With Suspected Worms Discharged From the Urethra—A Case Study

Clinical Case Reports
A 58‐year‐old female presented with a 6‐month history of recurrent “worms” found in her toilet, which she suspected originated from her urinary tract. Physical examination was unremarkable.
Shuqian Cai, Xiaoping Xu, Junchi Xue, Yifei Hu   +3 more
doaj   +1 more source