Results 81 to 90 of about 853,706 (301)

Developing a Questionnaire to Investigate Monthly Human Errors Among Railway Traffic Control Room Employees [PDF]

open access: yesIranian Rehabilitation Journal
Objectives: The working situation of railway traffic control rooms (RTCR) employees makes them susceptible to human error. On the other hand, the occurrence of human error by these staff can lead to catastrophic events.
Soleiman Ramezanifar   +4 more
doaj  

Statefinder Revisited

open access: yes, 2005
The quality of supernova data will dramatically increase in the next few years by new experiments that will add high-redshift supernova to the currently known ones.
Ishida, Emille E. O.
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Watch out for neurosyphilis, which is easily misdiagnosed or missed in diagnosis

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2016
DOI: 10.3969/j.issn.1672-6731.2016.07 ...
Ming-li RAO, Shuo HUANG, Xi-ying FU
doaj  

Diagnostic errors in psychiatry

open access: yesComprehensive Psychiatry, 1978
Abstract Although the importance of nosology has been derided as "pigeonholing" by some American psychiatrists, the science of diagnosis has lately enjoyed a renaissance. Actually, whether or not a psychiatrist possessed diagnostic acumen had little effect on the outcome of treatment until the past two decades, because so much of treatment was ...
J R, Morrison, T A, Flanagan
openaire   +2 more sources

The ionisation parameter of star-forming galaxies evolves with the specific star formation rate

open access: yes, 2018
We investigate the evolution of the ionisation parameter of star-forming galaxies using a high-redshift ($z\sim 1.5$) sample from the FMOS-COSMOS survey and matched low-redshift samples from the Sloan Digital Sky Survey.
Bian, Fuyan   +6 more
core   +1 more source

From Focus on Sounds to Focus on Words in English Pronunciation Instruction [PDF]

open access: yes, 2010
The authors present a report on the experiment in which a group of 25 Polish secondary school pupils has undergone a special training in the pronunciation of 50 commonly mispronounced words with the use of special, teacher-designed materials.
Stasiak, Sławomir   +1 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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