Results 41 to 50 of about 1,679,146 (250)

PSMA immunohistochemistry as a diagnostic biomarker of hepatocellular carcinoma

JHEP Reports
Background & Aims: A combination of three immunohistological markers (Glypican 3, heat shock protein 70 [HSP70], and glutamine synthetase [GS]) is routinely used to differentiate hepatocellular carcinoma (HCC), but this panel’s sensitivity is ...
Killian Véron, Etienne Becht, Astrid Laurent-Bellue, Rémy Nicolle, Miguel Albuquerque, Samira Laouirem, Hélène Cazier, Clément Bailly, Mohamed Bouattour, Mickaël Lesurtel, Catherine Guettier, Rachida Lebtahi, Valérie Vilgrain, Valérie Paradis, Jérôme Cros, Aurélie Beaufrère   +15 more
doaj   +1 more source

Diagnostic immunohistochemistry in gynaecological neoplasia : A brief survey of the most common scenarios [PDF]

, 2017
Immunohistochemistry is a valuable adjunct in routine gynaecological pathology. The molecular revolution has redesigned knowledge of gynaecological cancers and refined histological classification.
Ayse Ayhan, Elisabetta Kuhn, Kuhn E., Ayhan A.   +3 more
core   +1 more source

Diagnostic accuracy of core biopsies of renal masses: Experience in a real-life setting from a tertiary center.

, 2021
Objective: To document and analyze diagnostic accuracy of renal core biopsy (RCB), its diagnostic correlation with resection specimens, and to question the need for immunohistochemistry (IHC) in the preoperative diagnosis of renal masses.
Ozluk, Yasemin, Erdem, Selçuk, Kilicaslan, Isin, Buyuk, Melek, Ozcan, Faruk, Karatay, Huseyin, Altay, Ali Yilmaz, Bakir, Baris   +7 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Diagnostic accuracy of p53 immunohistochemistry as surrogate of TP53 sequencing in endometrial cancer [PDF]

, 2020
Aberrant p53 immunohistochemical expression is used to identify the copy-number-high/TP53-mutant subgroup of endometrial cancer (EC). We aimed to determine the diagnostic accuracy of p53 immunohistochemistry as surrogate for TP53 sequencing through a ...
Travaglino, Antonio, Insabato, Luigi, Cerbone, Marco, Zullo, Fulvio, Turco, Maria Caterina, Di Maio, Anna, De Marco, Margot, Russo, Daniela, Raffone, Antonio, De Luca, Caterina   +9 more
core   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Diagnostic accuracy of SOX11 immunohistochemistry in mantle cell lymphoma: A meta-analysis.

PLoS ONE, 2019
SOX11 is a transcription factor that is normally expressed in the fetal brain and has also been detected in some malignant tumors, including mantle cell lymphoma (MCL).
Woojoo Lee, Eun Shin, Bo-Hyung Kim, Hyunchul Kim   +3 more
doaj   +1 more source

Antigen retrieval immunohistochemistry and molecular morphology in the year 2001

, 2001
The impact of the antigen retrieval (AR) technique upon diagnostic immunohistochemistry (IHC) and upon research has been demonstrated by numerous of articles and more than a dozen major reviews.
Shi, S R, Cote, R J, Taylor, C R
core   +1 more source

Immunohistochemistry

, 2021
One of nine datasets for the project "neural substrates of reinforcement", where Drosophila fruit flies self-stimulate with light to optogenetically activate Chrimson channels in dopaminergic ...
Björn Brembs (96464)
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source